Results 41 to 50 of about 32,706 (236)
Metadata Extraction and Management in Data Lakes With GEMMS
In addition to volume and velocity, Big data is also characterized by its variety. Variety in structure and semantics requires new integration approaches which can resolve the integration challenges also for large volumes of data.
Christoph Quix, Rihan Hai, Ivan Vatov
doaj +1 more source
Unveiling Global Diversity of Patescibacteriota and Functional Interactions with Host Microbes
Patescibacteriota represents a diverse group of ultra‐small epibiotic bacteria, which is largely overlooked. By integrating ribosomal protein S3‐based community profiling with MAG‐based metabolic potential analyses, this study provides new insights into their distribution, diversity, and potential interactions with other bacteria across diverse ...
Yanhan Ji +12 more
wiley +1 more source
Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen +8 more
wiley +1 more source
Mettertron – Bridging Metadata Repositories and Terminology Servers [PDF]
Jan Schladetzky +4 more
openalex +1 more source
CELLama is created, a framework that harnesses language models to convert cellular data into “sentences” that represent gene expression and metadata, enabling a universal embedding of cells. Unlike most single‐cell foundation models, CELLama supports scalable analysis and offers flexible applications including spatial transcriptomics.
Jeongbin Park +7 more
wiley +1 more source
Microbial synthesis of nanomaterials (NMs) is eco‐friendly, but the screening of microorganisms is limited by inefficient traditional methods (currently only involving∽400 microorganisms/90 NMs). We propose AI framework MicrobeDiscover, integrating a knowledge graph of microbe‐NM interactions.
Ludi Wang +12 more
wiley +1 more source
In the era of interdisciplinary research supported by IT solutions, a special role is played by digital source repositories. The digital turn has contributed to their considerable development, and the application of new technologies has largely changed ...
Zawadzki Mateusz
doaj +1 more source
This study uncovers a recipient‐derived monocyte‐to‐macrophage trajectory that drives inflammation during kidney transplant rejection. Using over 150 000 single‐cell profiles and more than 850 biopsies, the authors identify CXCL10+ macrophages as key predictors of graft loss.
Alexis Varin +16 more
wiley +1 more source
Large language models are transforming microbiome research by enabling advanced sequence profiling, functional prediction, and association mining across complex datasets. They automate microbial classification and disease‐state recognition, improving cross‐study integration and clinical diagnostics.
Jieqi Xing +4 more
wiley +1 more source
Based on ''Guidelines for metadata creation and management in the Institutional Repositories'' (CRUI, Italy, 2012) and ''LODE-BD Recommendations'' (AIMS, 2012), and exploring other principles and strategies for qualitative development of metadata ...
Iryna Solodovnik
doaj +6 more sources

