Results 111 to 120 of about 64,104 (342)

Bridging the Semantic Gap with SQL Query Logs in Natural Language Interfaces to Databases

open access: yes, 2019
A critical challenge in constructing a natural language interface to database (NLIDB) is bridging the semantic gap between a natural language query (NLQ) and the underlying data. Two specific ways this challenge exhibits itself is through keyword mapping
Baik, Christopher   +2 more
core   +1 more source

Single‐Cell Dissection of Tumor‐Infiltrating Lymphocytes Reveals Cellular Architecture Predictive of Therapeutic Efficacy in Acral Melanoma

open access: yesAdvanced Science, EarlyView.
Autologous tumor‐infiltrating lymphocyte (TIL) therapy shows promising efficacy in acral melanoma, yet determinants of durable response remain unclear. By integrating single‐cell transcriptomics and TCR sequencing, this study reveals that TIL products enriched for T follicular helper and intermediate exhausted T cells establish persistent clonal ...
Chao Zhang   +12 more
wiley   +1 more source

ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology

open access: yesAdvanced Science, EarlyView.
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li   +25 more
wiley   +1 more source

Medical Content Searching, Retrieving, and Sharing Over the Internet: Lessons Learned From the mEducator Through a Scenario-Based Evaluation

open access: yesJournal of Medical Internet Research, 2015
BackgroundThe mEducator Best Practice Network (BPN) implemented and extended standards and reference models in e-learning to develop innovative frameworks as well as solutions that enable specialized state-of-the-art medical educational content to be ...
Antoniades, Athos   +10 more
doaj   +1 more source

Toward Prostate Cancer Early Warning with a Self‐Powered Wearable Biosensing Platform Integrated with Machine Learning

open access: yesAdvanced Science, EarlyView.
ABSTRACT Current prostate cancer detection methods remain limited in non‐invasiveness and specificity, prompting interest in urinary biomarkers such as sarcosine. Here, we report a urine‐powered wearable platform for non‐invasive sarcosine detection as a proof‐of‐concept for decentralized early warning.
Jing Xu   +10 more
wiley   +1 more source

Describing Geospatial Assets in the Web of Data: A Metadata Management Scenario

open access: yesISPRS International Journal of Geo-Information, 2016
Metadata management is an essential enabling factor for geospatial assets because discovery, retrieval, and actual usage of the latter are tightly bound to the quality of these descriptions. Unfortunately, the multi-faceted landscape of metadata formats,
Cristiano Fugazza   +5 more
doaj   +1 more source

Information Environment Metadata Schema Registry [PDF]

open access: yes, 2009
Several metadata schemas focusing on Dublin Core metadata are now in operation around the world. In this demonstration, we support participants in exploring various components that make up the IEMSR metadata schema registry: a desktop tool enabling creation of simple DC vocabularies and application profiles and their addition to the registry; a Web ...
Emma Tonkin, Alexey Strelnikov
openaire   +1 more source

Adamant: a JSON schema-based metadata editor for research data management workflows

open access: gold, 2022
Ihda Chaerony Siffa   +2 more
openalex   +1 more source

Peroxidase‐Mimicking Nanozymes for Rapid Detection of Infectious Diseases

open access: yesAdvanced Science, EarlyView.
Peroxidase‐mimicking nanozymes (PMNs) have emerged as robust and versatile materials for rapid infectious disease diagnostics. This review highlights the rational design and controlled synthesis of PMNs, summarizes key biomarkers relevant to infectious diseases, examines their integration into diverse rapid detection platforms, and highlights ...
Shikuan Shao   +5 more
wiley   +1 more source

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