Results 91 to 100 of about 11,467 (253)

Metadata functional requirements for genomic data practice and curation

Information Research: An International Electronic Journal
Introduction. The rapid accumulation of genomic data and their widespread reuse in clinical and scientific practice demands more effective description and organization of genomic information, which poses new challenges in developing metadata schemas ...
Hong Huang, Jian Qin
doaj   +3 more sources

An exciting Approach to Theoretical Spectroscopy

Advanced Science, EarlyView.
ABSTRACT Theoretical spectroscopy, and more generally, electronic‐structure theory, are powerful concepts for describing the complex many‐body interactions in materials. They cover methods from ground‐state properties to lattice excitations and light‐matter interaction, including time‐resolved variants.
Martí Raya‐Moreno, Alexander Buccheri, Noah Alexy Dasch, Nasrin Farahani, Ignacio Gonzalez Oliva, Andris Gulans, Seokhyun Hong, Manoar Hossain, Hannah Kleine, Martin Kuban, Sven Lubeck, Benedikt Maurer, Pasquale Pavone, Fabian Peschel, Daria Popova‐Gorelova, Lu Qiao, Elias Richter, Santiago Rigamonti, Ronaldo Rodrigues Pela, Maximilian Schebek, Kshitij Sinha, Daniel T. Speckhard, Jan Stutz, Sebastian Tillack, Dmitry Tumakov, Jānis Užulis, Mara Voiculescu, Cecilia Vona, Mao Yang, Claudia Draxl   +29 more
wiley   +1 more source

CHCHD10 Mitigates Alzheimer's Disease‐Related Phenotypes in Association With Epigenetic Remodeling in Directly Reprogrammed Neurons

Advanced Science, EarlyView.
CHCHD10 loss in Alzheimer's disease is associated with mitochondrial dysfunction, epigenomic disruption, and tau pathology. Restoration of CHCHD10 shifts DNA methylation toward a non‐disease state and reduces tau and amyloid pathology, with KATNAL2 acting as a downstream effector.
Teresa M. Thomas, Ching‐Yao Yang, Kexin Zhang, Liam Wetzel, Dina Bugybayeva, Julia Ferguson, Md Mahmudul Hasan, William Samsa, Nandita Patil, Anshul Dash, Tarini Gowda, Xiongwei Zhu, Feixiong Cheng, Tian Liu   +13 more
wiley   +1 more source

Metadata Schema Used in OCLC Sampled Web Pages [PDF]

Jiàoyù zīliào yǔ túshūguǎn xué, 2005
The tremendous growth of Web resources has made information organization and retrieval more and more difficult. As one approach to this problem, metadata schemas have been developed to characterize Web resources.
Fei Yu
doaj  

Dual‐Wavelength Control of Charge Accumulation in Rubrene Microcrystals with Anisotropic Conductivity

Advanced Science, EarlyView.
Rubrene microcrystals, forming two distinct sector types, are investigated using photoemission electron spectroscopy. The two sectors exhibit a built‐in charge landscape, arising from anisotropic conductivities. Upon excitation with UV light, the diamond‐shaped sectors accumulate significant charge, whereas the triangular sectors remain essentially ...
Moha Naeimi, Ingo Barke, Sylvia Speller
wiley   +1 more source

An Integrative Strategy Delineates Modular Metabolic Remodeling and Potential Therapeutic Targets Across Metabolic Diseases

Advanced Science, EarlyView.
An integrative single‐cell atlas across multiple metabolic diseases reveals coordinated metabolic modules and disease‐shared versus disease‐specific pathway activities. By systematically comparing scoring strategies, a robust RankAve framework is established. Coupled with network analysis and drug‐target prediction, this resource uncovers cross‐disease
Kuan Yang, Congxue Hu, Hang Zhao, Xiao Peng, Yiming Yan, Jiasi Wang, Wenqi Jiang, Depeng Mu, Yan Cao, Xia Li, Yunpeng Zhang   +10 more
wiley   +1 more source

IDI Search: a metadata search app for exploring New Zealand’s administrative linked data

International Journal of Population Data Science
How can we lower barriers to reuse of linked administrative data and improve quality at the same time? Linked data resources are expensive and complex, but accompanying readily-accessible metadata supports data reuse and quality control.
Tom Elliott, Barry Milne, Eileen Li, Andrew Sporle, Colin Simpson   +4 more
doaj   +1 more source

Single‐Cell and Spatial Transcriptomics Unveil Key Regulators Governing Cell Differentiation for Schistosoma japonicum Sexual Development

Advanced Science, EarlyView.
Using single‐cell and spatial transcriptomics, we identified key regulators that govern cell differentiation involved in parasite development and egg laying in Schistosoma japonicum. This comprehensive study establishes a foundational resource for understanding schistosome biology, deciphers the regulatory programs underlying cell differentiation and ...
Zhigang Lu, Xiaoxu Wang, Shun Li, Xuxin Li, Pengfei Du, Yameng Zheng, Lu Liu, Yanyan Zhang, Omri Wurtzel, Guofeng Cheng   +9 more
wiley   +1 more source

Metadata schema

This deliverable will provide scheme definitions, and detail related concepts regarding metadata management for both data stored in the cloud as well as user defined data annotations, including the security vocabulary needed to support appropriate access control mechanisms.
openaire   +3 more sources

Engineering Human Donor Derived Germinal Center‐Like Organoids (GCLOs) for Studying Immune Response to Vaccination

Advanced Science, EarlyView.
We bioengineered a new approach methodology of generating Germinal Center Organoids that self‐organize from human blood‐derived immune cells. These immune organoids reproduce key features of humoral immunity, IgG production, and plasmablast emergence.
Bhumi Suthar, Carlos Gomez, Giancarlo Asencio, Suresh Pallikkuth, Ashutosh Agarwal   +4 more
wiley   +1 more source