Results 211 to 220 of about 71,233 (313)

Integrative cross‐tissue analysis unveils complement‐immunoglobulin augmentation and dysbiosis‐related fatty acid metabolic remodeling during mammalian aging

iMeta, Volume 4, Issue 3, June 2025.
Our study provides a comprehensive multi‐omics profile of aging, integrating proteomic, metabolomic, and metagenomic analyses across diverse tissues and plasma. We identified the synergistic amplification of the circulating complement system and tissue‐wide immunoglobulin accumulation as key molecular drivers of inflammaging.
Feng Zhang, Rong Li, Yasong Liu, Jinliang Liang, Yihang Gong, Cuicui Xiao, Jianye Cai, Tingting Wang, Qiang You, Jiebin Zhang, Haitian Chen, Jiaqi Xiao, Yingcai Zhang, Yang Yang, Hua Li, Jia Yao, Qi Zhang, Jun Zheng   +17 more
wiley   +1 more source

Microbes with higher metabolic independence are enriched in human gut microbiomes under stress. [PDF]

Elife
Veseli I, Chen YT, Schechter MS, Vanni C, Fogarty EC, Watson AR, Jabri B, Blekhman R, Willis AD, Yu MK, Fernàndez-Guerra A, Füssel J, Eren AM.   +12 more
europepmc   +1 more source

TerraGenome: a consortium for the sequencing of a soil metagenome

, 2009
Timothy M. Vogel, Pascal Simonet, Janet Jansson, P. R. Hirsch, James M. Tiedje, Jan Dirk van Elsas, Mark Bailey, Renaud Nalin, Laurent Philippot   +8 more
openalex   +1 more source

The microbiologist's guide to metaproteomics

iMeta, Volume 4, Issue 3, June 2025.
Metaproteomics within the multi‐omics framework provides a comprehensive view of microbial systems by identifying proteins, quantifying their levels, detecting posttranslational modifications (PTMs), mapping protein–protein interactions (PPIs), and localizing proteins.
Tim Van Den Bossche, Jean Armengaud, Dirk Benndorf, Jose Alfredo Blakeley‐Ruiz, Madita Brauer, Kai Cheng, Marybeth Creskey, Daniel Figeys, Lucia Grenga, Timothy J. Griffin, Céline Henry, Robert L. Hettich, Tanja Holstein, Pratik D. Jagtap, Nico Jehmlich, Jonghyun Kim, Manuel Kleiner, Benoit J. Kunath, Xuxa Malliet, Lennart Martens, Subina Mehta, Bart Mesuere, Zhibin Ning, Alessandro Tanca, Sergio Uzzau, Pieter Verschaffelt, Jing Wang, Paul Wilmes, Xu Zhang, Xin Zhang, Leyuan Li, The Metaproteomics Initiative   +31 more
wiley   +1 more source

Prokaryotic cellulase gene clusters derived from 2,305 metagenomes. [PDF]

Sci Data
Song B, Tria FDK, Skejo J.
europepmc   +1 more source

Human Pathogens Abundant in the Bacterial Metagenome of Cigarettes

, 2009
Amy R. Sapkota, Sibel Berger, Timothy M. Vogel   +2 more
openalex   +1 more source

MetaVelvet: an extension of Velvet assembler to de novo metagenome assembly from short sequence reads [PDF]

, 2012
Toshiaki Namiki, Tsuyoshi Hachiya, Hideaki L Tanaka, Yasubumi Sakakibara   +3 more
openalex   +1 more source

Leveraging core enzyme structures for microbiota targeted functional regulation: Urease as an example

iMeta, Volume 4, Issue 3, June 2025.
We present an innovative methodology that integrates core enzyme identification, protein structural characterization, regulator virtual screening, and functional validation to achieve precise microbiome functional regulation. As a proof of concept, we focused on the regulation of urea decomposition by the rumen microbiota in ruminants. This methodology
Shengguo Zhao, Huiyue Zhong, Yue He, Xiaojiao Li, Li Zhu, Zhanbo Xiong, Xiaoyin Zhang, Nan Zheng, Diego P. Morgavi, Jiaqi Wang   +9 more
wiley   +1 more source

CloudLCA: finding the lowest common ancestor in metagenome analysis using cloud computing [PDF]

, 2012
Guoguang Zhao, Dechao Bu, Changning Liu, Jing Li, Jian Yang, Zhiyong Liu, Yi Zhao, Runsheng Chen   +7 more
openalex   +1 more source

Insights into the physiology of Methylotenera mobilis as revealed by metagenome-based shotgun proteomic analysis

, 2009
Gundula Bosch, Tiansong Wang, Ekaterina Latypova, Marina Kalyuzhnaya, Murray Hackett, Ludmila Chistoserdova   +5 more
openalex   +1 more source