Results 91 to 100 of about 133,465 (266)

Metagenomic Contigs - Protein Sequences

, 2022
Protein sequences obtained from metagenomic contigs.
Lindsay Putman (10525586)
core   +1 more source

Gut Microbial Release of Ferulic Acid From Germinated Quinoa Alleviates Obesity‐Associated Cognitive Impairment by Activating Hippocampal Mitophagy Associated with PINK1/Parkin Pathway

Advanced Science, EarlyView.
Liberation of ferulic acid by gut microbial feruloyl esterase mediates cognitive enhancement of germinated quinoa (GQF) on obese mice. Ferulic acid enriched in GQF is released by gut microbes Roseburia hominis and R. intestinalis and subsequently mediates the neuroprotective effects of GQF on obesity‐induced cognitive decline by activating hippocampal ...
Yongli Lan, Wengang Zhang, Lei Wang, Shiyang Zhao, Yujie Song, Xinze Wang, Yutang Wang, Xijuan Yang, Shaobo Ma, Junlin Ge, Rui Guo, Xuebo Liu   +11 more
wiley   +1 more source

Pasta, a Versatile Transcriptomic Clock, Maps the Chemical and Genetic Determinants of Aging and Rejuvenation

Advanced Science, EarlyView.
Pasta is a transcriptomic aging clock built on an age‐shift learning framework and trained on 17 000 samples across 21 datasets. It accurately predicts relative biological age across tissues, platforms, and species, captures stemness‐to‐senescence transitions, and identifies age‐modulatory perturbations.
Jérôme Salignon, Maria Tsiokou, Patricia Marqués, Enriqueta Rodríguez‐Diaz, Hazel Ang, Federico Pietrocola, Christian G. Riedel   +6 more
wiley   +1 more source

Vaginal Microbiota Is Stable throughout the Estrous Cycle in Arabian Mares

Animals, 2020
Lactic acid bacteria (LAB) dominate human vaginal microbiota and inhibit pathogen proliferation. In other mammals, LAB do not dominate vaginal microbiota, however shifts of dominant microorganisms occur during ovarian cycle.
Marta Barba, Rebeca Martínez-Boví, Juan José Quereda, María Lorena Mocé, María Plaza-Dávila, Estrella Jiménez-Trigos, Ángel Gómez-Martín, Pedro González-Torres, Belén Carbonetto, Empar García-Roselló   +9 more
doaj   +1 more source

Deep Clustering for Metagenomic Binning [PDF]

, 2022
Deep learning is an area that is onlysparsely explored for metagenomic bin-ning. The existing deep learning-basedapproaches usually preprocess raw DNAsequences into input features such as com-position and abundance and perform rep-resentation learning ...
Fichte, Jan Niklas, Polásková, Jitka, Ha, Trong Dai   +2 more
core  

Gut‐Liver Translocation of Bacteroides Uniformis Alleviates Advanced Metabolic Dysfunction‐Associated Steatotic Liver Disease by Suppressing Hepatocyte Ferroptosis via Propionic Acid Secretion

Advanced Science, EarlyView.
Systematic characterization of the liver‐resident microbiota in advanced metabolic dysfunction‐associated steatotic liver disease (MASLD) reveals a consistent depletion of Bacteroides uniformis (B. uniformis) in both hepatic and gut microbial communities. Oral gavage of B.
Haiyang Liu, Zun Fan, Zhen Liu, Lei Qin, Xin Zhao   +4 more
wiley   +1 more source

Unveiling the Taxonomic Diversity and Unprecedented Biosynthetic Treasure of the Phylum Myxococcota

Advanced Science, EarlyView.
Natural products remain vital sources of therapeutics, and the phylum Myxococcota constitutes an especially rich reservoir for them. Based on decades of microbiological efforts, we present 154 new Myxococcota genomes and revise taxonomy quadrupling the number of families and genera.
Amay Ajaykumar Agrawal, Ronald Garcia, Guangyi Chen, Chantal D. Bader, Peter Sullivan, Alexander Popoff, Daniel Krug, Maja Hunter, Sebastian Walesch, Emilia Oueis, Christine Frank, Haowen Zhao, Joachim J. Hug, Sebastian Keller, Pascal Hirsch, Azat Tagirdzhanov, Tatiana Malygina, Mary Victory E. Gutierrez, Alexey Gurevich, Judith Boldt, Boyke Bunk, Jörg Overmann, Ulrich Nübel, Andreas Keller, Olga V. Kalinina, Rolf Müller   +25 more
wiley   +1 more source

Meeting report : 1st international functional metagenomics workshop May 7–8, 2012, St. Jacobs, Ontario, Canada [PDF]

, 2012
This report summarizes the events of the 1st International Functional Metagenomics Workshop. The workshop was held on May 7 and 8 in St. Jacobs, Ontario, Canada and was focused on building a core international functional metagenomics community, exploring
David R. Rose, Charles, Trevor, Valla, Svein, Reid, Alexandra, Kornelia Smalla, John Doemer, Edwards, Elizabeth A., Smalla, K., Alexandra Reid, Katja Engel, Moreno-Hagelsieb, Gabriel, Charles, Trevor C., Cheng-Cang Wu, Trevor C. Charles, Reid, A., Sean F. Brady, Sjöling, Sara, Liles, Mark R., Brady, Sean F., Sara Sjöling, Sjöling, Sara,, David A. Mead, Eric C. Martens, O’gara, Fergal, Streit, Wolfgang R., Sessitsch, Angela, Wellington, Elizabeth M.H., Edwards, E. A., Simonet, Pascal, Jennifer Tedman-Jones, O’Gara, F., Neufeld, Joseph D., Wolfgang R. Streit, Ashby, Deborah, Elizabeth A. Edwards, Wu, Cheng-Cang, Wellington, Elizabeth, Neufeld, Josh D., Fiebig, Klaus, Tedman-Jones, Jennifer, Martens, Erik C., Martens, Eric C., Angela Sessitsch, Engel, Katja, Doemer, John, Fergal O’Gara, Cowan, Don A., Miyazaki, Kentaro, Klaus Fiebig, Elizabeth M. H. Wellington, Pascal Simonet, Don A. Cowan, Rose, David R., Mark R. Liles, Smalla, Kornelia, Josh D. Neufeld, Wellington, Elizabeth M. H., Svein Valla, Kentaro Miyazaki, Gabriel Moreno-Hagelsieb, Deborah Ashby, Dennis McCormac, Wellington, E. M. H., McCormac, Dennis, O'Gara, Fergal, Mead, David A.   +65 more
core   +1 more source

Rainfall Shapes the Diversity of Soil Nitrogen‐Fixing Microorganisms Worldwide

Advanced Science, EarlyView.
This study reveals the distinctive pattern and mechanism of rainfall driving the global biodiversity and biogeography of soil potential N‐fixing microorganisms, and constructs the theoretical framework. The results guide us on how to maintain ecosystem productivity under future climate changes (e.g., whether a specific region needs more N fertilizers ...
Bin Hua, Shuang Pang, Ang Li, Zonghao Hu, Honghui Wu, Shuhan Zhang, Yi Fan, Yi Wu, Wei Yang, Yachao Zhao, Yupeng Guan, Baoming Ji, Deliang Kong, Yong Zhao, Anton A. Goncharov, Anastasia Yu. Korotkevich, Rong Mao, Yang Zhang, Ximei Zhang   +18 more
wiley   +1 more source

WTAP Transcriptional Suppression by KLF9 Drives Osteoclastogenesis via M6A‐Mediated Regulation of CSF1R Signaling in Estrogen‐Deficient Osteoporosis

Advanced Science, EarlyView.
Scheme of the KLF9/WTAP/YTHDF2/m6A/CSF1R regulatory axis in osteoclastogenesis and estrogen‐deficient osteoporosis. WTAP‐mediated m6A modification of Csf1r mRNA governs osteoclastogenesis via a YTHDF2‐mediated pathway. Pathological upregulation of KLF9 drives Wtap transcription, leading to increased m6A deposition on the 3’‐UTR of Csf1r mRNA.
Chen Shen, Xin Liu, Gaoran Ge, Li Xu, Ziyu Zhang, Chang Lv, Hao Xu, Wenhao Li, Yi Qin, Qifeng Sheng, Qihan Wang, Hongxia Li, Jun Zhou, Huilin Yang, Dechun Geng   +14 more
wiley   +1 more source