Results 81 to 90 of about 173,492 (295)

Gut Lactate Boosts Ruminococcus via Histone Lactylation to Mediate Time‐Restricted Feeding Protection in Crohn's Disease

open access: yesAdvanced Science, EarlyView.
TRF enriches Ruminococcus, a bacterial genus producing SCFAs, and activates the epithelial HIF‐1α signaling pathway. This mechanism protects the colonic mucosa from inflammatory insults in colitis models. Mechanistically, gut lactate production during starvation and refeeding mediates H4K12la, which increases SLC9A3 expression and creates an acidic gut
Linwen Huang   +17 more
wiley   +1 more source

Analysis of the composition and function of rhizosphere microbial communities in plants with tobacco bacterial wilt disease and healthy plants

open access: yesMicrobiology Spectrum
To explore the factors influencing the occurrence of bacterial wilt, the differences in the physicochemical properties, microbial community composition and function between rhizosphere soil of tobacco plants with bacterial wilt and healthy plants in the ...
Bingye Yang   +10 more
doaj   +1 more source

Exploring nucleo-cytoplasmic large DNA viruses in Tara Oceans microbial metagenomes [PDF]

open access: yes, 2013
Nucleo-cytoplasmic large DNA viruses (NCLDVs) constitute a group of eukaryotic viruses that can have crucial ecological roles in the sea by accelerating the turnover of their unicellular hosts or by causing diseases in animals. To better characterize the
Acinas, Silvia G.   +27 more
core   +1 more source

Translational metagenomics [PDF]

open access: yesJournal of Translational Medicine, 2021
Selvasankar Murugesan   +1 more
openaire   +3 more sources

Diversity of Pharmaceuticals Enhances Antibiotic Resistance in the Invertebrate Gut via Biofilm‐Mediated Mechanisms

open access: yesAdvanced Science, EarlyView.
Pharmaceutical diversity acts as an independent driver of antibiotic resistance in soil invertebrates. While bulk soil remains unaffected, the collembolan gut microbiome exhibits significant resistance gene enrichment under complex chemical exposure and diurnal warming.
Yi‐Fei Wang   +11 more
wiley   +1 more source

Metagenomics [PDF]

open access: yesNature Biotechnology, 2019
Gaurav Saxena   +3 more
  +6 more sources

Global perspectives on the biodegradation of LDPE in agricultural systems

open access: yesFrontiers in Microbiology
The increasing use of plastics globally has generated serious environmental and human health problems, particularly in the agricultural sector where low-density polyethylene (LDPE) and other plastics are widely used.
Jani E. Mendoza   +10 more
doaj   +1 more source

The fecal resistome of dairy cattle is associated with diet during nursing. [PDF]

open access: yes, 2019
Antimicrobial resistance is a global public health concern, and livestock play a significant role in selecting for resistance and maintaining such reservoirs.
DePeters, Edward J   +7 more
core   +1 more source

Characterization of wild and captive baboon gut microbiota and their antibiotic resistomes [PDF]

open access: yes, 2018
Antibiotic exposure results in acute and persistent shifts in the composition and function of microbial communities associated with vertebrate hosts.
Boolchandani, Manish   +9 more
core   +2 more sources

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

open access: yesAdvanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey   +6 more
wiley   +1 more source

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