Results 91 to 100 of about 149,188 (270)
A Vavilovian approach to discovering crop-associated microbes with potential to enhance plant immunity [PDF]
, 2014 Through active associations with a diverse community of largely non-pathogenic microbes, a plant may be thought of as possessing an “extended genotype,” an interactive cross-organismal genome with potential, exploitable implications for plant immunity ...
Broders, Kirk +2 more
core +3 more sources
Population scale nucleic acid delivery to Caenorhabditis elegans via electroporation
G3: Genes, Genomes, Genetics, 2021 Genetic manipulations, like RNAi, CRISPR/Cas9- and array-based transgenesis depend on initial delivery of nucleic acids. Microinjection is effective for germline delivery, but limited by targeting each animal individually.
Anastasia S Khodakova +4 more
doaj +1 more source
Case study of the intestinal microbiota using the XGN-MBI metagenomic assay [PDF]
, 2019 The microbiota of the colon and rectum is the most abundant and diverse of the human body, with a density of up to 1-2 kg of weight and a diversity that exceeds a thousand species.
Burgos-Molina, Antonio Manuel +4 more
core
Bioinformatics tools for analysing viral genomic data [PDF]
, 2016 The field of viral genomics and bioinformatics is experiencing a strong resurgence due to high-throughput sequencing (HTS) technology, which enables the rapid and cost-effective sequencing and subsequent assembly of large numbers of viral genomes.
Davison, A. +7 more
core +1 more source
Journal of Genetic Engineering and Biotechnology, 2022 Background Mondia whitei root is often used in Africa as a local therapeutic agent for libido enhancement. The fractions of the M. whitei leaves (MWL) lack chemical characterization of their bioactive components and possible molecular targets.
Hope Onohuean +7 more
doaj +1 more source
Commet: comparing and combining multiple metagenomic datasets [PDF]
arXiv, 2015 Metagenomics offers a way to analyze biotopes at the genomic level and to reach functional and taxonomical conclusions. The bio-analyzes of large metagenomic projects face critical limitations: complex metagenomes cannot be assembled and the taxonomical or functional annotations are much smaller than the real biological diversity.
arxiv
Towards complete representation of bacterial contents in metagenomic samples [PDF]
arXiv, 2022 Background: In the metagenome assembly of a microbiome community, we may think abundant species would be easier to assemble due to their deeper coverage. However, this conjucture is rarely tested. We often do not know how many abundant species we are missing and do not have an approach to recover these species.
arxiv
Spaced seeds improve k-mer-based metagenomic classification [PDF]
, 2015 Metagenomics is a powerful approach to study genetic content of environmental samples that has been strongly promoted by NGS technologies. To cope with massive data involved in modern metagenomic projects, recent tools [4, 39] rely on the analysis of k ...
Brinda, Karel +2 more
core +2 more sources
CLMB: deep contrastive learning for robust metagenomic binning [PDF]
arXiv, 2021 The reconstruction of microbial genomes from large metagenomic datasets is a critical procedure for finding uncultivated microbial populations and defining their microbial functional roles. To achieve that, we need to perform metagenomic binning, clustering the assembled contigs into draft genomes. Despite the existing computational tools, most of them
arxiv
Promises and Prospects of Microbiome Studies [PDF]
, 2015 Since Anthony van Leeuwenhoek, first microscopic observations of the unseen microbiota and the more recent realization that little of the microbes in the biosphere are known, humans have developed a deep curiosity to fully understand the inner workings ...
Izard, Jacques, Rivera, Maria C.
core +1 more source