Results 141 to 150 of about 91,219 (305)

Focus on Metagenomics [PDF]

open access: yesJournal of Biomolecular Techniques : JBT, 2017
Christopher E, Mason, Scott, Tighe
openaire   +2 more sources

Precision medicine in paediatrics: Progress and priorities

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain   +3 more
wiley   +1 more source

Advanced In Vitro Platforms for Experimental Liver Research: From Organoids and Liver‐on‐Chip to Omics and Artificial Intelligence

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Hepatocytes perform essential physiological functions in the human body. Gaining more profound insight into the liver structure, diseases, and physiology by using in vitro models can help to propose more relevant clinical applications. Conventional in vitro liver models, such as two‐dimensional (2D) cell cultures, fail to adequately replicate ...
Seyedeh Kiana Teymorian   +3 more
wiley   +1 more source

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

open access: yesBMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen   +9 more
wiley   +1 more source

Fimsbactin Siderophores From a South African Marine Sponge Symbiont, Marinomonas sp. PE14‐40

open access: yesMicrobial Biotechnology
Low iron levels in marine habitats necessitate the production of structurally diverse siderophores by many marine bacterial species for iron acquisition.
Nompumelelo Philile Praiseworth Ikegwuoha   +7 more
doaj   +1 more source

Beyond antimicrobials: Ecological nano‐strategies for rebalancing dysbiotic oral microbial homeostasis

open access: yesBMEMat, EarlyView.
Oral microbial homeostasis, a dynamic host‐microbe balance, is vital in infectious diseases. Conventional antibiotics often disrupt this homeostasis, spurring interest in nanomaterials for oral microbial homeostasis rebalancing. This review outlines nanomaterial strategies across three ecological levels (population/community, ecosystem, and cross ...
Chen Hu   +10 more
wiley   +1 more source

Defect‐engineered tungsten oxide nanowires as redox‐metabolic nanozymes for gut inflammation‐infection syndromes

open access: yesBMEMat, EarlyView.
Defect‐engineered WO3 nanowires serve as a multifunctional nanozyme platform to treat IBD complicated by Salmonella co‐infection. By integrating catalytic ROS/RNS scavenging and targeted metabolic interference of pathogens via molybdenum substitution, these nanowires effectively resolve intestinal oxidative stress, inhibit infection, and restore ...
Yifan Yuan   +13 more
wiley   +1 more source

From Ecological States to Trajectories: Revealing Ecological Dynamics Through Environmental Nucleic Acids

open access: yesBiological Diversity, EarlyView.
Environmental nucleic acids (eNA) observations integrate temporal and ecological information across multiple dimensions of an ecological state. Repeated and complementary observations extend biomonitoring from state assessment toward reconstruction of ecological trajectories, including their direction, rate, pathways, progression, recovery, and ...
Wei Xiong, Aibin Zhan
wiley   +1 more source

Enzymatic Electrosynthesis for Sustainable CO2 Conversion: Advancing Circular Carbon Economy

open access: yesCarbon Energy, EarlyView.
Enzymatic electrosynthesis (EES) offers molecular precision in synthesizing value‐added products from CO2. We highlight its distinct edge over alternative enzyme‐hybrid systems and analyze electron transfer pathways. Key strategies to overcome electron transfer bottlenecks and expand product diversity are addressed, and also data‐driven approaches for ...
Yan Xie   +7 more
wiley   +1 more source

‘Metagenomics 2.0’ [PDF]

open access: yesEnvironmental Microbiology Reports, 2015
openaire   +2 more sources

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