Results 11 to 20 of about 62,719 (262)
Metagenomics and antibiotics [PDF]
Clinical Microbiology and Infection, 2012 Most of the bacterial species that form part of the biosphere have never been cultivated. In this situation, a comprehensive study of bacterial communities requires the utilization of non-culture-based methods, which have been named metagenomics.
Garmendia, L. +3 more
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DNA Research, 2022 Abstract Various microorganisms exist in environments, and each of which has an optimal growth temperature (OGT). The relationship between genomic information and OGT of each species has long been studied, and one such study revealed that OGT of prokaryotes can be accurately predicted based on the fraction of seven ...
Masaomi Kurokawa +6 more
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Nature Reviews Genetics, 2019 Clinical metagenomic next-generation sequencing (mNGS), the comprehensive analysis of microbial and host genetic material (DNA and RNA) in samples from patients, is rapidly moving from research to clinical laboratories. This emerging approach is changing how physicians diagnose and treat infectious disease, with applications spanning a wide range of ...
Charles Y. Chiu, Steven A. Miller
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Journal of Health, Population and Nutrition, 2023 Background Cholera can result in the expulsion of important microbiota from the gut and result in death if left untreated. The disease transmits mainly via drinking water carrying Vibrio cholerae; and household contacts (HHC) of cholera patients are at ...
Shirajum Monira +18 more
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Antioxidants, 2021 Diabetes mellitus and related complications are among the most important problems of the world-leading healthcare systems. Despite their priority, molecular and genetic aspects of diabetes pathogenesis are poorly understood; however, the involvement of ...
Yuliya Dvoretskaya +4 more
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PLoS Computational Biology, 2010 Metagenomics is a discipline that enables the genomic study of uncultured microorganisms. Faster, cheaper sequencing technologies and the ability to sequence uncultured microbes sampled directly from their habitats are expanding and transforming our view of the microbial world.
Bourne, Philip E. +3 more
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Metagenomics and probiotics [PDF]
Clinical Microbiology and Infection, 2012 The development of extensive sequencing methods has allowed metagenomic studies on the human gut microbiome to be carried out. This has tremendously increased our knowledge on gut microbiota composition and activity, allowing microbiota aberrations related to different diseases to be identified.
Gueimonde Fernández, Miguel +1 more
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DNA structure at the plasmid origin-of-transfer indicates its potential transfer range
Scientific Reports, 2018 Horizontal gene transfer via plasmid conjugation enables antimicrobial resistance (AMR) to spread among bacteria and is a major health concern. The range of potential transfer hosts of a particular conjugative plasmid is characterised by its mobility ...
Jan Zrimec, Aleš Lapanje
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BMC Genomics, 2023 Background While genome-resolved metagenomics has revolutionized our understanding of microbial and genetic diversity in environmental samples, assemblies of short-reads often result in incomplete and/or highly fragmented metagenome-assembled genomes ...
Sophie A. Simon +5 more
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Critical Assessment of Metagenome Interpretation—a benchmark of metagenomics software [PDF]
Nature Methods, 2017 ISSN:1548 ...
Sczyrba, Alexander +66 more
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