Results 191 to 200 of about 149,337 (415)

Effect of Probiotic Bacteria on the Gut Microbiome of Mice with Lipopolysaccharide-Induced Inflammation

Microorganisms
The role of lipopolysaccharide (LPS) in the development of diseases is clear, but the specific mechanisms remain poorly understood. This study aimed to investigate the microbiome aberrations in the guts of mice against the background of LPS, as well as ...
Mariya Gryaznova, Inna Burakova, Yuliya Smirnova, Polina Morozova, Egor Chirkin, Artem Gureev, Evgeny Mikhaylov, Olga Korneeva, Mikhail Syromyatnikov   +8 more
doaj   +1 more source

Metagenomics for studying unculturable microorganisms: cutting the Gordian knot. [PDF]

, 2005
Patrick D. Schloss, Jo Handelsman
openalex   +1 more source

Improving saliva shotgun metagenomics by chemical host DNA depletion

Microbiome, 2018
BackgroundShotgun sequencing of microbial communities provides in-depth knowledge of the microbiome by cataloging bacterial, fungal, and viral gene content within a sample, providing an advantage over amplicon sequencing approaches that assess taxonomy ...
C. Marotz, J. Sanders, C. Zuñiga, L. Zaramela, R. Knight, K. Zengler   +5 more
semanticscholar   +1 more source

Construction of Reporter Phage T4::Nluc and Its Application in the Detection of Escherichia coli in Urinary Tract Infections

iLABMED, EarlyView.
A reporter phage T4::Nluc was constructed using the CRISPR/Cas9 system combined with homologous recombination and was applied for the detection of clinical Escherichia coli in urinary tract infections (UTIs). T4::Nluc exhibited superior sensitivity and specificity, and had a short detection time, making it a powerful tool for diagnosing UTIs.
Zhiyun Hao, Minwei Li, Qiang Zhao, Liye Wang, Ting Liu, Chi Wang, Chengbin Wang   +6 more
wiley   +1 more source

Frontiers in soil ecology—Insights from the World Biodiversity Forum 2022

Journal of Sustainable Agriculture and Environment, Volume 1, Issue 4, Page 245-261, December 2022., 2022
Abstract Global change is affecting soil biodiversity and functioning across all terrestrial ecosystems. Still, much is unknown about how soil biodiversity and function will change in the future in response to simultaneous alterations in climate and land use, as well as other environmental drivers.
Nico Eisenhauer, S. Franz Bender, Irene Calderón‐Sanou, Franciska T. de Vries, Jonas J. Lembrechts, Wilfried Thuiller, Diana H. Wall, Romy Zeiss, Mohammad Bahram, Rémy Beugnon, Victoria J. Burton, Thomas W. Crowther, Manuel Delgado‐Baquerizo, Stefan Geisen, Paul Kardol, Valentyna Krashevska, Carlos A. Martínez‐Muñoz, Guillaume Patoine, Julia Seeber, Nadejda A. Soudzilovskaia, Michael Steinwandter, Marie Sünnemann, Xin Sun, Marcel G. A. van der Heijden, Carlos A. Guerra, Anton Potapov   +25 more
wiley   +1 more source

MegIS: High-Performance, Energy-Efficient, and Low-Cost Metagenomic Analysis with In-Storage Processing [PDF]

arXiv
Metagenomics has led to significant advances in many fields. Metagenomic analysis commonly involves the key tasks of determining the species present in a sample and their relative abundances. These tasks require searching large metagenomic databases. Metagenomic analysis suffers from significant data movement overhead due to moving large amounts of low-
arxiv  

A human skin microbiome reference catalog and the skin microbial landscape of plateau adults

iMetaOmics, EarlyView.
Understanding the skin microbiome is crucial for elucidating its role in health and disease. However, comprehensive studies on the genetic and functional diversity of the skin microbiome in individuals living in extreme environments remain scarce. This work explores the unique characteristics and functional adaptations of the plateau skin microbiome ...
Yi Liu, Zhiming Li, Chao Zhang, Bo Li, Weiwei Jiang, Hang Li, Lei Zhang, Hefu Zhen, Shujun Bao, Xiong Li, Yinuo Liu, Xianzhen Chen, Jinxia Du, Jingjing Xia, Jiucun Wang, Ruijin Guo, Yuzhe Sun, Bo Pan, Wenzhi Lei, Liang Xiao, Jin Zhao, Xin Jin, Wenwei Zhang, Xiaogang Liu, Jian Wang, Min Chen, Wanqing Liao, Wenjie Fang, Chao Nie, Weihua Pan   +29 more
wiley   +1 more source

Multiple Comparative Metagenomics using Multiset k-mer Counting [PDF]

arXiv, 2016
Background. Large scale metagenomic projects aim to extract biodiversity knowledge between different environmental conditions. Current methods for comparing microbial communities face important limitations. Those based on taxonomical or functional assignation rely on a small subset of the sequences that can be associated to known organisms.
arxiv  

Novel machine‐learning bioinformatics reveal distinct metabolic alterations for enhanced colorectal cancer diagnosis and monitoring

iMetaOmics, EarlyView.
The PANDA pipeline for colorectal cancer (CRC) analysis integrates metabolomic data from LC‐MS with machine learning techniques to classify CRC stages and predict biomarkers. Initially, the raw metabolomic data is processed using partial least squares discriminant analysis (PLS‐DA) to reduce dimensionality and highlight key features.
Rui Xu, Hyein Jung, Fouad Choueiry, Shiqi Zhang, Rachel Pearlman, Heather Hampel, Ning Jin, Jieli Li, Jiangjiang Zhu   +8 more
wiley   +1 more source

Deciphering comprehensive profiles of pathogenies and resistome of pork using integrating metagenomic and isolation strategies

iMetaOmics, EarlyView.
The pork microbiome was investigated using an integrated approach combining isolation and metagenomic sequencing methods to comprehensively analyze the pathogens and resistome on pork surfaces. The study revealed a large number and diversity of pathogens and resistance genes, potentially originating from air, transportation, water, or cross ...
Lianwei Ye, Qiao Hu, Tao Zang, Yaling Wang, Heng Heng, Edward Wai Chi Chan, Sheng Chen   +6 more
wiley   +1 more source