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StrainMake: reproducible hybrid metagenomics with MAG recovery and strain-level resolution. [PDF]

open access: yesBioinformatics
Hennecart B   +4 more
europepmc   +1 more source

Clinical metagenomics [PDF]

open access: yesNature Reviews Genetics, 2019
Clinical metagenomic next-generation sequencing (mNGS), the comprehensive analysis of microbial and host genetic material (DNA and RNA) in samples from patients, is rapidly moving from research to clinical laboratories. This emerging approach is changing how physicians diagnose and treat infectious disease, with applications spanning a wide range of ...
Charles Chiu, Chiu Charles Y
exaly   +5 more sources
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Metagenomics

Letters in Applied Microbiology, 2008
The total number of prokaryotic cells on earth has been estimated to be approximately 4-6 x 10(30), with the majority of these being uncharacterized. This diversity represents a vast genetic bounty that may be exploited for the discovery of novel genes, entire metabolic pathways and potentially valuable end-products thereof.
R D, Sleator, C, Shortall, C, Hill
openaire   +3 more sources

Comparative Metagenomics

2017
Thanks in large part to newer, better, and cheaper DNA sequencing technologies, an enormous number of metagenomic sequence datasets have been and continue to be generated, covering a huge variety of environmental niches, including several different human body sites.
Andrew, Maltez Thomas   +5 more
openaire   +2 more sources

Phage Metagenomics

2007
The vast majority of novel DNA sequences deposited in the databases now comes from environmental phage DNA sequences. Methods are presented for the cloning and sequencing of phage DNA that might otherwise be lethal to bacterial host vectors or contain modified DNA bases that prevent standard cloning of such sequences. In addition, methods are presented
Veronica, Casas, Forest, Rohwer
openaire   +2 more sources

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