Results 271 to 280 of about 130,645 (325)

Soil properties and road proximity likely influence plant and bacterial traits and diversity more than habitat size in small urban greenspaces

PLANTS, PEOPLE, PLANET, EarlyView.
The global decline in biodiversity can be partly ameliorated by sympathetic design of green spaces within urban environments. This includes roundabouts on road systems. This study utilised a combination of approaches to assess levels of plant and bacterial diversity in roundabouts of varying size, soil characteristics and habitat complexity.
Ethan Mitchell‐Innes, Brady Locke‐King, Michelle L. Davis, Paul Ashton, Ellen L. Fry   +4 more
wiley   +1 more source

Rhizosphere microbial detoxification and phosphorus solubilization drive ecological remediation of Pb–Zn contaminated soils

PLANTS, PEOPLE, PLANET, EarlyView.
Heavy metal contamination of soils poses a serious threat to ecosystem health and food security worldwide. This study investigated how native plants, such as Artemisia annua and Buddleja davidii, interact with soil microbes in Pb–Zn waste slag areas. We found that these plants stimulate microbes, which improve phosphorus availability and reduce metal ...
Caili Sun, Yajuan Yao, Yongwei Liu, Xiaoyu Lu   +3 more
wiley   +1 more source

Novel applications of the tomato microbiome: Roles and considerations for agriculture, human health, and society

PLANTS, PEOPLE, PLANET, EarlyView.
Plants, like humans, have a microbiome that helps them grow, defend themselves against pathogens, acquire nutrients, and protect themselves against environmental stresses. The microbiome of tomatoes, a staple crop grown worldwide, could be utilized not only to reduce fertilizer and pesticide applications, but also to clean up harmful pollutants ...
Sean Lindert, Kathryn Kingsley, Peerapol Chiaranunt, James F. White   +3 more
wiley   +1 more source

CASP16 Protein Monomer Structure Prediction Assessment

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The assessment of monomer targets in the Critical Assessment of Structure Prediction Round 16 (CASP16) underscores that the problem of single‐domain protein fold prediction is nearly solved—no target folds were incorrectly predicted across all Evaluation Units.
Rongqing Yuan, Jing Zhang, Andriy Kryshtafovych, R. Dustin Schaeffer, Jian Zhou, Qian Cong, Nick V. Grishin   +6 more
wiley   +1 more source

Structure Modeling Protocols for Protein Multimer and RNA in CASP16 With Enhanced MSAs, Model Ranking, and Deep Learning

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT We present the methods and results of our protein complex and RNA structure predictions at CASP16. Our approach integrated multiple state‐of‐the‐art deep learning models with a consensus‐based scoring method. To enhance the depth of multiple sequence alignments (MSAs), we employed a large metagenomic sequence database.
Yuki Kagaya, Tsukasa Nakamura, Jacob Verburgt, Anika Jain, Genki Terashi, Pranav Punuru, Emilia Tugolukova, Joon Hong Park, Anouka Saha, David Huang, Daisuke Kihara   +10 more
wiley   +1 more source

Highlights of Model Quality Assessment in CASP16

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Model quality assessment (MQA) remains a critical component of structural bioinformatics for both structure predictors and experimentalists seeking to use predictions for downstream applications. In CASP16, the Evaluation of Model Accuracy (EMA) category featured both global and local quality estimation for multimeric assemblies (QMODE1 and ...
Alisia Fadini, Recep Adiyaman, Shaima N. Alhaddad, Behnosh Behzadi, Jianlin Cheng, Xinyue Cui, Nicholas S. Edmunds, Lydia Freddolino, Ahmet G. Genc, Fang Liang, Dong Liu, Jian Liu, Quancheng Liu, Liam J. McGuffin, Pawan Neupane, Chunxiang Peng, David R. Shortle, Meng Sun, Haodong Wang, Qiqige Wuyun, Guijun Zhang, Xuanfeng Zhao, Wei Zheng, Randy J. Read   +23 more
wiley   +1 more source

Ozonated irrigation in vineyards: limited effects on soil bacterial and fungal microbiota

Pest Management Science, EarlyView.
Irrigation with ozonated water caused slight changes in bacterial composition but did not significantly affect microbial diversity, beneficial microbes (plant growth‐promoting bacteria, arbuscular mycorrhizal fungi), or grapevine trunk disease‐related pathogens.
David Labarga, Andreu Mairata, Miguel Puelles, David Gramaje, Alícia Pou   +4 more
wiley   +1 more source

Resveratrol attenuates areca nut extract‐induced chronic colitis by suppressing pyroptosis of intestinal epithelial cells via modulating cGAS/STING signaling

VIEW, EarlyView.
Areca nut extract (ANE), commonly consumed in some cultures, can damage gut cells by triggering inflammation and cell death through a pathway called cGAS‐STING. This leads to the release of harmful inflammatory substances and weakens the gut barrier. Our study shows that resveratrol, a natural compound found in foods like grapes, can block this harmful
Jing Zhang, Muhammad Tufail, Yu‐Qi Huang, Can‐Hua Jiang, Ning Li   +4 more
wiley   +1 more source

Silibinin‐driven microbial and metabolic reprogramming restores CD4+ T cell immunity in HIV immunological nonresponders

VIEW, EarlyView.
Despite efficacious antiretroviral therapy, 10%–40% of HIV‐infected individuals exhibit inadequate immune reconstitution due to persistent inflammatory activation and NAD+ metabolic dysregulation—a critical cofactor in cellular bioenergetics. We administered silibinin to 53 HIV immunological non‐responders and elucidated its mechanism through selective
Wenli Liu, Minghui An, Qi Wang, Yuxin Shang, Shuyao Zang, Haibo Ding, Shuai Fu, Yun Liu, Xue Dong, Xiao Yang, Jinna Dai, Xiaoxu Han, Yingchun Xu, Hong Shang   +13 more
wiley   +1 more source

Postauricular Skin Mycobiome Profiles in Atopic Dermatitis Treated With Dupilumab or Cyclosporine A: A Descriptive Case Series

The Journal of Dermatology, EarlyView.
ABSTRACT Atopic dermatitis (AD) essentially exhibits dysbiosis of skin fungal microbiome, mycobiome, characterized by depletion of Malassezia. The effects of recent systemic therapies for AD on skin mycobiome were not understood enough. We examined changes of skin mycobiome before and after systemic treatments with anti‐IL‐4Rα antibody (dupilumab: DUP)
Yuta Koike, Hitomi Morisaki, Daisuke Motooka, Mai Matsumoto, Motoi Takenaka, Hiroyuki Murota   +5 more
wiley   +1 more source