Antioxidants, 2021 Diabetes mellitus and related complications are among the most important problems of the world-leading healthcare systems. Despite their priority, molecular and genetic aspects of diabetes pathogenesis are poorly understood; however, the involvement of ...
Yuliya Dvoretskaya +4 more
doaj +1 more source
Meeting report : 1st international functional metagenomics workshop May 7–8, 2012, St. Jacobs, Ontario, Canada [PDF]
, 2012 This report summarizes the events of the 1st International Functional Metagenomics Workshop. The workshop was held on May 7 and 8 in St. Jacobs, Ontario, Canada and was focused on building a core international functional metagenomics community, exploring
Ashby, Deborah +26 more
core +7 more sources
Characterisation of three novel α-L-arabinofuranosidases from a compost metagenome
BMC Biotechnology, 2019 Background The importance of the accessory enzymes such as α-L-arabinofuranosidases (AFases) in synergistic interactions within cellulolytic mixtures has introduced a paradigm shift in the search for hydrolytic enzymes.
Brent Fortune +5 more
doaj +1 more source
Combination of Whole Genome Sequencing and Metagenomics for Microbiological Diagnostics
International Journal of Molecular Sciences, 2022 Whole genome sequencing (WGS) provides the highest resolution for genome-based species identification and can provide insight into the antimicrobial resistance and virulence potential of a single microbiological isolate during the diagnostic process.
Srinithi Purushothaman +2 more
semanticscholar +1 more source
Fast and sensitive taxonomic classification for metagenomics with Kaiju
Nature Communications, 2016 Metagenomics emerged as an important field of research not only in microbial ecology but also for human health and disease, and metagenomic studies are performed on increasingly larger scales.
P. Menzel, K. Ng, A. Krogh
semanticscholar +1 more source
Bracken: estimating species abundance in metagenomics data
bioRxiv, 2016 We describe a new, highly accurate statistical method that computes the abundance of species in DNA sequences from a metagenomics sample. Bracken (Bayesian Reestimation of Abundance after Classification with KrakEN) uses the taxonomy labels assigned by ...
Jennifer Lu +3 more
semanticscholar +1 more source
The Human Virome: Viral Metagenomics, Relations with Human Diseases, and Therapeutic Applications
Viruses, 2022 The human body is colonized by a wide range of microorganisms. The field of viromics has expanded since the first reports on the detection of viruses via metagenomic sequencing in 2002. With the continued development of reference materials and databases,
Geng-Hao Bai +3 more
semanticscholar +1 more source
Proteomics as the final step in the functional metagenomics study of antimicrobial resistance [PDF]
, 2015 peer-reviewedThe majority of clinically applied antimicrobial agents are derived from natural products generated by soil microorganisms and therefore resistance is likely to be ubiquitous in such environments.
Cotter, Paul D. +4 more
core +1 more source
Complementary Metagenomic Approaches Improve Reconstruction of Microbial Diversity in a Forest Soil. [PDF]
, 2020 Soil ecosystems harbor diverse microorganisms and yet remain only partially characterized as neither single-cell sequencing nor whole-community sequencing offers a complete picture of these complex communities.
Alteio, LV +12 more
core +3 more sources
From metagenomics to the metagenome: Conceptual change and the rhetoric of translational genomic research [PDF]
, 2009 As the international genomic research community moves from the tool-making efforts of the Human Genome Project into biomedical applications of those tools, new metaphors are being suggested as useful to understanding how our genes work – and for ...
Huss, John Edward, Juengst, Eric Thomas
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