Results 21 to 30 of about 162,178 (247)

The Human Virome: Viral Metagenomics, Relations with Human Diseases, and Therapeutic Applications

Viruses, 2022
The human body is colonized by a wide range of microorganisms. The field of viromics has expanded since the first reports on the detection of viruses via metagenomic sequencing in 2002. With the continued development of reference materials and databases,
Geng-Hao Bai, Sheng‐Chieh Lin, Yi-Hsiang Hsu, Shih-Yuen Chen   +3 more
semanticscholar   +1 more source

Simple statistical identification and removal of contaminant sequences in marker-gene and metagenomics data

Microbiome, 2017
The accuracy of microbial community surveys based on marker-gene and metagenomic sequencing (MGS) suffers from the presence of contaminants—DNA sequences not truly present in the sample.
N. M. Davis, Diana M Proctor, S. Holmes, D. Relman, B. Callahan   +4 more
semanticscholar   +1 more source

Characterisation of three novel α-L-arabinofuranosidases from a compost metagenome

BMC Biotechnology, 2019
Background The importance of the accessory enzymes such as α-L-arabinofuranosidases (AFases) in synergistic interactions within cellulolytic mixtures has introduced a paradigm shift in the search for hydrolytic enzymes.
Brent Fortune, Sizwe Mhlongo, Leonardo Joaquim van Zyl, Robert Huddy, Mariette Smart, Marla Trindade   +5 more
doaj   +1 more source

Gut microbiota shifts favorably with delivery of handwashing with soap and water treatment intervention in a prospective cohort (CHoBI7 trial)

Journal of Health, Population and Nutrition, 2023
Background Cholera can result in the expulsion of important microbiota from the gut and result in death if left untreated. The disease transmits mainly via drinking water carrying Vibrio cholerae; and household contacts (HHC) of cholera patients are at ...
Shirajum Monira, Indrajeet Barman, Fatema Tuz Jubyda, Sk. Imran Ali, Aminul Islam, Kazi Mohammad Zillur Rahman, Mahamud-ur Rashid, Fatema-Tuz Johura, Marzia Sultana, Fatema Zohura, Sazzadul Islam Bhuyian, Tahmina Parvin, David Sack, Tahmeed Ahmed, K M Saif-Ur-Rahman, Maqsud Hossain, Haruo Watanabe, Christine Marie George, Munirul Alam   +18 more
doaj   +1 more source

Mitochondrial Antioxidant SkQ1 Has a Beneficial Effect in Experimental Diabetes as Based on the Analysis of Expression of microRNAs and mRNAs for the Oxidative Metabolism Regulators

Antioxidants, 2021
Diabetes mellitus and related complications are among the most important problems of the world-leading healthcare systems. Despite their priority, molecular and genetic aspects of diabetes pathogenesis are poorly understood; however, the involvement of ...
Yuliya Dvoretskaya, Victor Glanz, Mariya Gryaznova, Mikhail Syromyatnikov, Vasily Popov   +4 more
doaj   +1 more source

Fast and sensitive taxonomic classification for metagenomics with Kaiju

Nature Communications, 2016
Metagenomics emerged as an important field of research not only in microbial ecology but also for human health and disease, and metagenomic studies are performed on increasingly larger scales.
P. Menzel, K. Ng, A. Krogh
semanticscholar   +1 more source

Genome binning of viral entities from bulk metagenomics data

Nature Communications, 2021
Despite the accelerating number of uncultivated virus sequences discovered in metagenomics and their apparent importance for health and disease, the human gut virome and its interactions with bacteria in the gastrointestinal tract are not well understood.
Joachim Johansen, D. Plichta, J. Nissen, M. Jespersen, Shiraz A. Shah, Ling Deng, J. Stokholm, H. Bisgaard, D. Nielsen, S. Sørensen, S. Rasmussen   +10 more
semanticscholar   +1 more source

Meeting report : 1st international functional metagenomics workshop May 7–8, 2012, St. Jacobs, Ontario, Canada [PDF]

, 2012
This report summarizes the events of the 1st International Functional Metagenomics Workshop. The workshop was held on May 7 and 8 in St. Jacobs, Ontario, Canada and was focused on building a core international functional metagenomics community, exploring
Ashby, Deborah, Brady, Sean F., Charles, Trevor, Cowan, Don A., Doemer, John, Edwards, E. A., Engel, Katja, Fiebig, Klaus, Liles, Mark R., Martens, Eric C., McCormac, Dennis, Mead, David A., Miyazaki, Kentaro, Moreno-Hagelsieb, Gabriel, Neufeld, Josh D., O’Gara, F., Reid, A., Rose, David R., Sessitsch, Angela, Simonet, Pascal, Sjöling, Sara, Smalla, K., Streit, Wolfgang R., Tedman-Jones, Jennifer, Valla, Svein, Wellington, E. M. H., Wu, Cheng-Cang   +26 more
core   +6 more sources

Bracken: estimating species abundance in metagenomics data

bioRxiv, 2016
We describe a new, highly accurate statistical method that computes the abundance of species in DNA sequences from a metagenomics sample. Bracken (Bayesian Reestimation of Abundance after Classification with KrakEN) uses the taxonomy labels assigned by ...
Jennifer Lu, F. Breitwieser, P. Thielen, S. Salzberg   +3 more
semanticscholar   +1 more source

Targeted metagenomics of active microbial populations with stable-isotope probing [PDF]

, 2016
The ability to explore microbial diversity and function has been enhanced by novel experimental and computational tools. The incorporation of stable isotopes into microbial biomass enables the recovery of labeled nucleic acids from active microorganisms,
Abu Laban, Abu Laban, Albertsen, Alneberg, Antony, Bernard, Chapleur, Chemerys, Chen, Chen, Chen, Colin, Cébron, Dumont, Dumont, Eyice, Faoro, Ferrer, Fu, Grob, Gupta, Gutierrez, Héry, Imelfort, J Colin Murrell, Jayamani, Jennifer Pratscher, Josh D Neufeld, Kalyuhznaya, Kim, Kim, Kim, Laban, Lear, Lee, Lee, Li, Li, Li, Lu, Lueders, Lynch, Martin, Moussard, Neufeld, Neufeld, Neufeld, Neufeld, Nyyssonen, Osaka, Paes, Pinnell, Pinnell, Qian, Radajewski, Saidi-Mehrabad, Sara Coyotzi, Schwarz, Singleton, Singleton, Song, Sul, Tyson, Verastegui, Vieites, Wang, Woyke, Yin   +67 more
core   +1 more source