Results 61 to 70 of about 117,934 (343)

An overlooked phenomenon: complex interactions of potential error sources on the quality of bacterial de novo genome assemblies

BMC Genomics
Background Parameters adversely affecting the contiguity and accuracy of the assemblies from Illumina next-generation sequencing (NGS) are well described.
Zoltán Rádai, Alex Váradi, Péter Takács, Nikoletta Andrea Nagy, Nicholas Schmitt, Eszter Prépost, Gábor Kardos, Levente Laczkó   +7 more
doaj   +1 more source

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

FEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma, Mingfei Wang, Yanhu Feng, Wanqi Zhang, Wenbo Wang, Yanfeng Xie, Guixiang Kong, Jie Feng, Pengfei Wang, Qi Wang, Xiaojun Huang   +10 more
wiley   +1 more source

Hydrogen cyanide in the rhizosphere: not suppressing plant pathogens, but rather regulating availability of phosphate

Frontiers in Microbiology, 2016
Plant growth promoting rhizobacteria produce chemical compounds with different benefits for the plant. Among them, HCN is recognized as a biocontrol agent, based on its ascribed toxicity against plant pathogens.
Tomaž Rijavec, Tomaž Rijavec, Aleš Lapanje, Aleš Lapanje, Aleš Lapanje   +4 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

High‐Throughput Metagenomics for Identification of Pathogens in the Clinical Settings

Small Methods, 2020
The application of sequencing technology is shifting from research to clinical laboratories owing to rapid technological developments and substantially reduced costs.
Na Li, Q. Cai, Qing Miao, Zeshi Song, Yuan Fang, Bijie Hu   +5 more
semanticscholar   +1 more source

Clinical metagenomics assessments improve diagnosis and outcomes in community-acquired pneumonia

BMC Infectious Diseases, 2021
Background Identifying the causes of community-acquired pneumonia (CAP) is challenging due to the disease’s complex etiology and the limitations of traditional microbiological diagnostic methods.
F. Xie, Zhimei Duan, Weiqi Zeng, Shumei Xie, Mingzhou Xie, H. Fu, Qing Ye, Teng Xu, L. Xie   +8 more
semanticscholar   +1 more source

Metagenomics in Virology

, 2021
Metagenomics, i.e., the sequencing and analysis of genomic information extracted directly from clinical or environmental samples, has become a fundamental tool to explore the viral world. Against the background of an extensive viral diversity revealed by metagenomics across many environments, new sequence assembly approaches that reconstruct complete ...
Roux, Simon, Matthijnssens, Jelle, Dutilh, Bas E   +2 more
openaire   +3 more sources

The Phylogenetic Diversity of Metagenomes [PDF]

PLoS ONE, 2011
Phylogenetic diversity--patterns of phylogenetic relatedness among organisms in ecological communities--provides important insights into the mechanisms underlying community assembly. Studies that measure phylogenetic diversity in microbial communities have primarily been limited to a single marker gene approach, using the small subunit of the rRNA gene
Katherine S. Pollard, Steven W. Kembel, Jessica L. Green, Jessica L. Green, Jonathan A. Eisen   +4 more
openaire   +6 more sources

Research progress on the metabolic transformation of Shenling Baizhu San under the influence of the gut microbiota

Advanced Chinese Medicine, EarlyView.
Abstract The gut microbiota plays a pivotal role in maintaining host metabolic homeostasis and overall physiological functions. Shenling Baizhu San (SLBZS), a time‐honored classical prescription for tonifying Qi, strengthening the spleen, removing dampness, and arresting diarrhea, has shown broad clinical efficacy in digestive disorders.
Jinlan Di, Xiaochun Zhang
wiley   +1 more source

subMG automates data submission for metagenomics studies

BioData Mining
Background Publicly available metagenomics datasets are crucial for ensuring the reproducibility of scientific findings and supporting contemporary large-scale studies.
Tom Tubbesing, Andreas Schlüter, Alexander Sczyrba   +2 more
doaj   +1 more source