Results 181 to 190 of about 293,302 (294)

Metal homeostasis as a therapeutic lever: advancing metalloimmunology to remodel the tumor microenvironment and enhance cancer immunotherapy. [PDF]

Theranostics
Chen X, Wang Q, Zhang H, Wang Y, Zhu H.
europepmc   +1 more source

The Mechanism of Metal Homeostasis in Plants: A New View on the Synergistic Regulation Pathway of Membrane Proteins, Lipids and Metal Ions. [PDF]

Membranes (Basel), 2021
Wu D, Saleem M, He T, He G.
europepmc   +1 more source

Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome

Advanced Science, EarlyView.
By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang, Siqi Guo, Jing Li, Qianqian Huang, Jing Ning, Binbin Xia, Xun Lv, Xiang Liu, Zeyu Gao, Jine Li, Longchao Liu, Moshi Song, Jun Wang   +12 more
wiley   +1 more source

Discovery of Ionophoroantibiotics as a New Antibiotic Class Targeting Metal Homeostasis in Multidrug-Resistant <i>Neisseria gonorrhoeae</i>. [PDF]

ACS Infect Dis
Jen FE, El-Deeb IM, Edwards JL, Maggioni A, Jennings MP, von Itzstein M.   +5 more
europepmc   +1 more source

Emerging Roles of Metallothioneins in Beta Cell Pathophysiology: Beyond and Above Metal Homeostasis and Antioxidant Response. [PDF]

Biology (Basel), 2021
Bensellam M, Laybutt DR, Jonas JC.
europepmc   +1 more source

Synchrotron XRF Imaging Reveals Manganese Accumulation in the Golgi and Post‐Synapses of Neurons and Enhanced Uptake in Astrocytes

Advanced Science, EarlyView.
Despite widespread exposure, the mechanisms of manganese neurotoxicity remain poorly understood. Using correlative cryogenic fluorescence and synchrotron X‐ray fluorescence imaging techniques, we show that the Golgi apparatus is the primary accumulation site for manganese in both neurons and astrocytes, and that manganese targets the neuronal ...
Ines Kelkoul, Aiyarin Kittilukkana, Luis C. C. Huarte, Hiram Castillo‐Michel, Murielle Salome, Stéphane Roudeau, Pauline Belzanne, Matthieu Sainlos, Noémie Pied, Monica Fernandez‐Monreal, Daniel Choquet, Richard Ortega, Asuncion Carmona   +12 more
wiley   +1 more source

Dietary metal chelator, phytochelatin 2, increases selenium and alters metal homeostasis and associated lipid metabolism in the liver. [PDF]

Adv Redox Res
Jarrell ZR, Lee HY, Lee CM, Orr ML, Jones DP, Go YM.   +5 more
europepmc   +1 more source

Nutritive Manganese and Zinc Overdosing in Aging C. elegans Result in a Metallothionein-Mediated Alteration in Metal Homeostasis. [PDF]

Mol Nutr Food Res, 2021
Baesler J, Michaelis V, Stiboller M, Haase H, Aschner M, Schwerdtle T, Sturzenbaum SR, Bornhorst J.   +7 more
europepmc   +1 more source

Integration of Spatiotemporal Multi‐Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome‐Mediated Stress Adaptation

Advanced Science, EarlyView.
This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu, Ke Cao, Liping Guan, Aizhi Qin, Yong Li, Zihao Zhao, Yinpeng Zhang, Yaping Zhou, Lirong Wang, Xuwu Sun   +9 more
wiley   +1 more source

Respiratory Exposure to Lithium Nickel Manganese Cobalt Oxide Particles: Evidence for Toxicity and Disruption of Metal Homeostasis in Mice. [PDF]

Environ Health (Wash)
Zhang X, Ye X, Sun Q, Liu Q, Deng F, Gu W, Chen Y, Wang Y, Zhan X, Jin Y, Zhang R, Dai Y.   +11 more
europepmc   +1 more source