Results 41 to 50 of about 2,133,478 (281)

Plant Frataxin in Metal Metabolism

Frontiers in Plant Science, 2018
Frataxin is a highly conserved protein from prokaryotes to eukaryotes. Several functions related to iron metabolism have been postulated for this protein, including Fe-S cluster and heme synthesis, response to oxidative damage and oxidative ...
Diego F. Gomez-Casati, Maria V. Busi, Maria A. Pagani   +2 more
doaj   +1 more source

Predicting copper-, iron- and zinc-binding proteins in pathogenic species of the Paracoccidioides genus

Frontiers in Microbiology, 2015
Approximately one-third of all proteins have been estimated to contain at least one metal cofactor, and these proteins are referred to as metalloproteins.
Gabriel B Tristao, Leandro Prado Assunção, Luiz Paulo Araujo Santos, CLAYTON LUIZ BORGES, Mirelle Garcia Silva-Bailao, Célia Maria de Almeida Soares, Gabriele eCavallaro, Alexandre Melo BAILAO   +7 more
doaj   +1 more source

The Impact of Chromate on Pseudomonas aeruginosa Molybdenum Homeostasis

Frontiers in Microbiology, 2022
Acquisition of the trace-element molybdenum via the high-affinity ATP-binding cassette permease ModABC is essential for Pseudomonas aeruginosa respiration in anaerobic and microaerophilic environments.
Eve A. Maunders, Dalton H. Y. Ngu, Dalton H. Y. Ngu, Dalton H. Y. Ngu, Katherine Ganio, Sheikh I. Hossain, Bryan Y. J. Lim, Bryan Y. J. Lim, Bryan Y. J. Lim, Michael G. Leeming, Zhenyao Luo, Zhenyao Luo, Zhenyao Luo, Aimee Tan, Evelyne Deplazes, Evelyne Deplazes, Boštjan Kobe, Boštjan Kobe, Boštjan Kobe, Christopher A. McDevitt   +19 more
doaj   +1 more source

Zinc translocation from Zn-sufficient to Zn-deficient roots as an adaptation to heterogeneous Zn availability

BMC Plant Biology
Zinc is essential for plant development and human health. While the effects of soil nutrient heterogeneity on plant growth were studied for macronutrients, adaptive mechanisms for micronutrients like Zn remain largely unexplored.
Magdalena Pypka, Diana Davydenko, Katarzyna Sowa, Julia Maksymiuk, Paweł Wróbel, Tomasz Kołodziej, Paweł Korecki, Oskar Siemianowski   +7 more
doaj   +1 more source

New Perspectives on Oxidized Genome Damage and Repair Inhibition by Pro-Oxidant Metals in Neurological Diseases

Biomolecules, 2014
The primary cause(s) of neuronal death in most cases of neurodegenerative diseases, including Alzheimer’s and Parkinson’s disease, are still unknown.
Joy Mitra, Erika N. Guerrero, Pavana M. Hegde, Haibo Wang, Istvan Boldogh, Kosagi Sharaf Rao, Sankar Mitra, Muralidhar L. Hegde   +7 more
doaj   +1 more source

Roles of subcellular metal homeostasis in crop improvement

Journal of Experimental Botany, 2021
AbstractImprovement of crop production in response to rapidly changing environmental conditions is a serious challenge facing plant breeders and biotechnologists. Iron (Fe), zinc (Zn), manganese (Mn), and copper (Cu) are essential micronutrients for plant growth and reproduction.
Khurram Bashir, Zarnab Ahmad, Takanori Kobayashi, Motoaki Seki, Naoko K Nishizawa   +4 more
openaire   +2 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Homeostasis and synaptic scaling : a theoretical perspective [PDF]

, 2013
textAbstract The synaptic input received by neurons in cortical circuits is in constant flux. From both environmental sensory changes and learning mechanisms that modify synaptic strengths, the excitatory and inhibitory signals received by a post ...
Corey, Joseph Harrod
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