Results 201 to 210 of about 737,390 (249)
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Endeavour, 1979
Abstract With the exception of sodium, potassium, and calcium relatively little is known of the cellular control of metal ions. Nevertheless, this is demonstrably very important, because a large number of metals—iron, copper, and manganese, for example—are essential constituents of enzyme systems.
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Abstract With the exception of sodium, potassium, and calcium relatively little is known of the cellular control of metal ions. Nevertheless, this is demonstrably very important, because a large number of metals—iron, copper, and manganese, for example—are essential constituents of enzyme systems.
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Metal Ions and Metal Complexes in Alzheimer's Disease
Current Pharmaceutical Design, 2016Alzheimer's disease (AD) is the most common form of dementia that seriously affects daily life. Even if AD pathogenesis is still subject of debate, it is generally accepted that cerebral cortex plaques formed by aggregated amyloid-β (Aβ) peptides can be considered a characteristic pathological hallmark.
SPINELLO, Angelo +4 more
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Nature, 1960
IN a recent communication, Somers1 has again considered the hypothesis first proposed by Mathews2, that the toxicity of metal ions is related to the electrode potential of the metal. He has plotted the negative logarithms of the ED50 values of the applied molar concentrations of 21 elements for conidia of Alternaria tenuis against the electronegativity
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IN a recent communication, Somers1 has again considered the hypothesis first proposed by Mathews2, that the toxicity of metal ions is related to the electrode potential of the metal. He has plotted the negative logarithms of the ED50 values of the applied molar concentrations of 21 elements for conidia of Alternaria tenuis against the electronegativity
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Metal ion effects on ion channel gating
Quarterly Reviews of Biophysics, 20031. Introduction 3742. Metals in biology 3783. The targets: structure and function of ion channels 3804. General effects of metal ions on channels 3824.1 Three types of general effect 3824.2 The main regulators 3835. Effects on gating: mechanisms and models 3845.1 Screening surface charges (Mechanism A) 3875.1.1 The classical approach 3875.1.1.1 ...
Fredrik, Elinder, Peter, Arhem
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Metal-on-Metal: Ion Levels as an Intervention Strategy
Seminars in Arthroplasty, 2012Due to the wear-related problems with large diameter metal-on-metal THA components, ion levels of cobalt and chromium in blood or serum are used to identify bearings with high-wear rates. Threshold levels for critical concentrations for these two alloys are published and quite frequently revised.
Morlock, Michael +3 more
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Nature, 1959
THE relationship between the toxicity of metal cations and their physico-chemical properties has been considered in terms of electrode potential1,2, insolubility of the metal sulphide3, and electronegativity4. Danielli and Davies4 suggested that the toxicity of metal ions is determined by their ability to form un-ionized complexes with ionogenic ...
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THE relationship between the toxicity of metal cations and their physico-chemical properties has been considered in terms of electrode potential1,2, insolubility of the metal sulphide3, and electronegativity4. Danielli and Davies4 suggested that the toxicity of metal ions is determined by their ability to form un-ionized complexes with ionogenic ...
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Mutagenicity of metal ions in bacteria
Environmental Research, 1985The mutagenicity of 24 metal salts was investigated in plate incorporation and fluctuation assays with Salmonella TA strains or Escherichia coli WP2 uvrA pKm 101. Chromate(VI) and selenate(VI) ions were found to be mutagenic in plate incorporation assays employing conventional media.
A, Arlauskas +5 more
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Metal ion complexes of cytidinediphosphocholine
Biochemical and Biophysical Research Communications, 1976Abstract Cytidine-5′-diphosphocholine (CDPcholine) forms a complex with Mg 2+ and Mn 2+ ions as indicated by the broadened 31 P NMR peaks of CDPcholine in the presence of these ions. Additional evidence for the complex is the decrease in absorption at 360 nm when CDPcholine is added to solutions of 8-hydroxyquinoline and Mg 2+ .
G A, Cook, W D, Perry, H H, Daron
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Immobilized metal ion affinity chromatography: waltz of metal ions and biomacromolecules
Expert Review of ProteomicsImmobilized metal ion affinity chromatography (IMAC) is an effective method developed in the 1980s for the separation and purification of proteins. The system consists of a solid-phase matrix, a linking ligand, and a metal ion. The method is based on the ability of metal ions to bind specifically to certain specific amino acid residues of proteins ...
Rui Yan, Yan-Ming Xu, Andy T. Y. Lau
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Metal Ion Interactions with Opiates
Annual Review of Pharmacology and Toxicology, 1980A number of monovalent and divalent metal ions are known to be vital in the normal functioning of the nervous sytem. However, investigations into the roles of inorganic ions in the actions of narcotic drugs have so far largely involved studies of Ca2+ effects, although experimental evidence has sug gested that other ions such as Mg2+, Mn2+, Cu2+, and ...
D B, Chapman, E L, Way
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