Results 41 to 50 of about 540,832 (313)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Economic Analysis of a ROXY Pilot Plant Supporting Early Lunar Mission Architectures

Aerospace
The establishment of a sustained human presence on the Moon is critically dependent on the ability to utilize local resources, primarily the production of oxygen for life support and propellant. The ROXY (Regolith to Oxygen and metals conversion) process
Tehya F. Birch, Achim Seidel, James E. Johnson, Georg Poehle, Uday Pal   +4 more
doaj   +1 more source

Gas-Atomized Nickel Silicide Powders Alloyed with Molybdenum, Cobalt, Titanium, Boron, and Vanadium for Additive Manufacturing

Metals, 2023
Nickel silicides (NiSi) are renowned for their ability to withstand high temperatures and resist oxidation and corrosion in challenging environments.
Mohammad Ibrahim, Qiang Du, Even Wilberg Hovig, Geir Grasmo, Christopher Hulme, Ragnhild E. Aune   +5 more
doaj   +1 more source

Metal-reactive lymphocytes from individuals’ exhibit significant production of IL-17A/F compared with IFN-γ production to metal challenge.

, 2019
Supernatants were harvested on D 6 and assayed by ELISA for production of (A) IL-17A/F secretion in the absence/presence of metal challenge and/or IL-1Ra from n = 4 metal reactive individuals lymphocytes, and (B) percentage increase of secreted cytokines
Lauryn Samelko (424639), Joshua Jacobs (424643), Nadim James Hallab (44059), Marco S. Caicedo (424640)   +3 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Physical Modeling of Plastic Working Conditions for Rods of 7xxx Series Aluminum Alloys

Archives of Metallurgy and Materials, 2017
The continuing high level of demand for lightweight structural materials is the reason for the ever-growing interest in aluminum alloys. The main areas of application for aluminum alloys products are the aerospace and automotive industries. Production of
Dyja H., Tussupkaliyeva E., Bajor T., Laber K.   +3 more
doaj   +1 more source

Metal-reactive lymphocytes from individuals’ exhibit significant production of IL-17A/F to metal challenge.

, 2019
Supernatants were harvested on D 6 and assayed by ELISA for production of (A) IL-17A/F or (B) IFN-γ in the absence/presence of metal challenge and/or MCC950 (NLRP3 inhibitor) from n = 3 metal reactive individuals lymphocytes, and (C) IL-17A/F or (D) IFN ...
Lauryn Samelko (424639), Joshua Jacobs (424643), Nadim James Hallab (44059), Marco S. Caicedo (424640)   +3 more
core   +1 more source

From Powders to Dense Metal Parts: Characterization of a Commercial AlSiMg Alloy Processed through Direct Metal Laser Sintering [PDF]

, 2013
In this paper, a characterization of an AlSiMg alloy processed by direct metal laser sintering (DMLS) is presented, from the analysis of the starting powders, in terms of size, morphology and chemical composition, through to the evaluation of mechanical ...
Manfredi, Diego, Flaviana Calignano, Manickavasagam Krishnan, Elisa Ambrosio, Riccardo Canali, Ambrosio, Elisa, Atzeni, Eleonora, Diego Manfredi, Canali, Riccardo, Eleonora Atzeni   +9 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Investigations of Plasticity of Hard-Deformed Aluminium Alloys of 5xxx Series Using Torsion Plastometer

Archives of Metallurgy and Materials, 2016
This paper presents the results of the study aimed at determination of plasticity of selected grades of hard-deformed aluminium alloys of 5xxx series in terms of parameters characteristic for the process of extrusion.
Laber K., Kawałek A., Sawicki S., Dyja H., Borowski J., Leśniak D., Jurczak H.   +6 more
doaj   +1 more source