Results 51 to 60 of about 2,161,180 (295)

Gas Accretion via Lyman Limit Systems

, 2016
In cosmological simulations, a large fraction of the partial Lyman limit systems (pLLSs ...
A. Aguirre, A. B. Ford, A. B. Ford, A. Dekel, A. E. Shapley, A. Frebel, A. Glidden, A. H. Maller, A. J. Battisti, A. J. Fox, A. L. Muratov, A. Marasco, A. S. Hirschauer, A. Y. Kniazev, B. D. Oppenheimer, B. D. Oppenheimer, B. D. Savage, B. E. Penprase, B. J. Weiner, C. A. Tremonti, C. B. Wotta, C. C. Steidel, C. C. Steidel, C. C. Steidel, C. J. Akerman, C. J. Liang, C. L. Martin, C. Peroux, C. W. Churchill, C.-A. Faucher-Giguère, C.-A. Faucher-Giguère, D. A. Berg, D. Fabbian, D. Kereš, D. Kirkman, D. Kirkman, D. Kunth, D. Som, D. Som, D. Tytler, E. D. Skillman, F. Haardt, F. Haardt, F. Voort van de, F. Voort van de, G. C. Rudie, G. D. Becker, G. G. Kacprzak, G. G. Kacprzak, G. G. Kacprzak, G. J. Ferland, G. M. Voit, J. C. Howk, J. K. Werk, J. K. Werk, J. K. Werk, J. K. Werk, J. M. O’Meara, J. M. O’Meara, J. N. Bahcall, J. P. Grimes, J. Schaye, J. Schaye, J. T. Stocke, J. Tumlinson, J. Tumlinson, J. X. Prochaska, J. X. Prochaska, J. X. Prochaska, J. X. Prochaska, K. H. R. Rubin, K. H. R. Rubin, K. L. Cooksey, K. M. Lanzetta, K. R. Stewart, M. Pettini, M. Pettini, M. Rafelski, M. S. Peeples, N. Bouché, N. Bouché, N. H. M. Crighton, N. H. M. Crighton, N. H. M. Crighton, N. Lehner, N. Lehner, N. Lehner, N. Lehner, R. A. Jorgenson, R. A. Simcoe, R. A. Simcoe, R. Bordoloi, R. Bordoloi, R. Cooke, R. Davé, S. G. Zonak, S. L. Ellison, S. Muzahid, S. Muzahid, S. Quiret, S. Shen, S. Shen, T. Bensby, T. J. Cooper, T. M. Heckman, T. M. Tripp, T. M. Tripp, V. Bromm, V. Burns, W. L. W. Sargent   +109 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

The synchronous improvement of strength and plasticity (SISP) in new Ni-Co based disc superalloys by controling stacking fault energy

Scientific Reports, 2017
It is a great challenge to improve the strength of disc superalloys without great loss of plasticity together since the microstructures benefiting the strength always do not avail the plasticity.
H. Xu, Z. J. Zhang, P. Zhang, C. Y. Cui, T. Jin, Z. F. Zhang   +5 more
doaj   +1 more source

Anion-Dependent Construction of Two Hexanuclear 3D-4F Complexes with a Flexible Schiff Base Ligand [PDF]

, 2012
Two hexanuclear 3d-4f Ni-Eu and Cu-Eu complexes [Eu4Ni2L2(OAc)(12)(EtOH)(2)] (1) and [Eu4Cu2L2(OAc)(12)]center dot 2H(2)O (2) are reported which are formed from the salen type Schiff-base ligand H2L (H2L = N,N'-bis(3-methoxysalicylidene)butane-1,4 ...
Andruh, Assefa, Assefa, Barja, Blasse, Bradley J. Holliday, Chen, Christopher Chan, Cremades, Daniel Lam, Deng, Desmond Schipper, Eddaoudl, Guerriero, Hogerheide, Julie M. Stanley, Lam, Mass, Moulton, Nakamaru, Pasatoiu, Piguet, Piguet, Piguet, Qun Chen, Rawashdeh-Omary, Reany, Richard A. Jones, Sabbatini, Sakamoto, Sakamoto, Shengchun Chen, Wai-Kwok Wong, Winpenny, Wolcan, Wong, Xiaoping Yang, Xiaoyan Chen, Yang, Yang, Yang, Yang, Zanello   +42 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Giant linear strain gradient with extremely low elastic energy in a perovskite nanostructure array

Nature Communications, 2017
Inherent elastic strains are useful to tune the physical properties of functional materials but it is difficult to build. Here, Tanget al. report a fabrication of inhomogeneous strains with a linear gradient as giant as 106 per meter in a BiFeO3 ...
Y. L. Tang, Y. L. Zhu, Y. Liu, Y. J. Wang, X. L. Ma   +4 more
doaj   +1 more source

Designing defect-based qubit candidates in wide-gap binary semiconductors for solid-state quantum technologies

, 2017
The development of novel quantum bits is key to extend the scope of solid-state quantum information science and technology. Using first-principles calculations, we propose that large metal ion - vacancy complexes are promising qubit candidates in two ...
Galli, Giulia, Govoni, Marco, Ma, He, Seo, Hosung   +3 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

A vertical silicon-graphene-germanium transistor

Nature Communications, 2019
Graphene-base transistors were originally proposed for high-frequency applications, but the height of the emitter potential barrier limits the transistor performance towards the THz range. Here, the authors fabricate a vertical silicon-graphene-germanium
Chi Liu, Wei Ma, Maolin Chen, Wencai Ren, Dongming Sun   +4 more
doaj   +1 more source