Results 21 to 30 of about 2,315 (265)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Transferencia de metales suelo – planta en el cerro “El Toro”, Huamachuco, Perú
Manglar, 2019 En la minera informal del cerro “El Toro”, se establecieron tres puntos de muestreo, con la finalidad de determinar las plantas con potencial fitorremediaror, para ello se tomaron muestras de suelo superficial y se recolectaron plantas herbáceas ...
Narda Alarcón, Freddy Peláez
doaj +1 more source
Ge-conservación, 2021 Gracias a la revolución tecnológica que vive el campo de la documentación del patrimonio vemos cómo los registros 3D se consolidan como recurso documental y se extienden con infinidad de propósitos, entre ellos los estudios morfométricos.
Alba Fuentes Porto +3 more
doaj +1 more source
Metal–metal bonds in biology [PDF]
Journal of Inorganic Biochemistry, 2012 Nickel-containing carbon monoxide dehydrogenases, acetyl-CoA synthases, nickel-iron hydrogenases, and diron hydrogenases are distinct metalloenzymes yet they share a number of important characteristics. All are O(2)-sensitive, with active-sites composed of iron and/or nickel ions coordinated primarily by sulfur ligands.
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Aplicación de la nanofiltración y pervaporación en el tratamiento de aguas residuales
Tecnología en Marcha, 2016 Este trabajo trata sobre la aplicación de las tecnologías de membrana en el tratamiento de las aguas residuales o usadas. Las operaciones de membrana se aplican a numerosos problemas medioambientales como resultado de unas regulaciones más restrictivas ...
M. J. Mora +2 more
doaj +2 more sources
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
La terapia fotodinámica promete revolucionar el tratamiento del cáncer
Tecnociencia Chihuahua, 2023 El cáncer es una de las enfermedades que más afecta a la población mundial. Los tratamientos más aplicados son la cirugía, la radioterapia y la quimioterapia. La quimioterapia consiste en el uso de fármacos para destruir las células cancerosas.
Lucas Verget +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source