Results 111 to 120 of about 7,747 (222)
Using machine learning to differentiate between enzymatic and non-enzymatic metalloprotein sites
, 2023 Enzymes are biological catalysts with exceptional product specificity and the potential for unmatched speed-up of reaction rates. Although current wet-lab techniques are capable of detecting enzyme activity for over 8,000 biochemical reactions, the ...
Feehan, Ryan
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Lung India, 2009 Objective: To evaluate the effect of long term use of doxycycline in IPF patients. Materials and Methods: Patients of IPF, selected randomly from out patient services and diagnosed on the basis of HRCT chest, were put on doxycycline in an open ...
Bhattacharyya Parthasarathi +8 more
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Identifying Chelators for Metalloprotein Inhibitors Using a Fragment-Based Approach
, 2016 Fragment-based lead design (FBLD) has been used to identify new metal-binding groups for metalloenzyme inhibitors. When screened at 1 mM, a chelator fragment library (CFL-1.1) of 96 compounds produced hit rates ranging from 29% to 43% for five matrix ...
Melissa T. Miller (2235562) +3 more
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Scanning probe technology in metalloprotein and biomolecular electronics.
, 2004 The interfacing of man-made electronic components with specifically-folded biomacromolecules lies central not only to the development of sensory interfaces and potential new molecular-scale devices, but also enables us to analyse processes of great ...
Zhao, A +3 more
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Photoinduced metalloprotein electron-transfer in solid and in solution
, 1997 This dissertation consists of two parts: the electron-transfer reaction in solution and in sol-gel glasses. In the first part, circular dichroism and resonance Raman spectra were used to characterize the solution structure of a very important protein ...
Shen, Chengyu
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Probing metalloproteins by voltammetry
, 2006 Dynamic electrochemical methods, which have long held an important place among the techniques of the coordination chemist, have generally remained unexploited by those seeking to understand the complex and often elusive chemistry of metal centres in proteins.
openaire +2 more sources
Modeling and analysis of soybean (Glycine max. L) Cu/Zn, Mn and Fe superoxide dismutases
Genetics and Molecular Biology, 2013 Superoxide dismutase (SOD, EC 1.15.1.1) is an important metal-containing antioxidant enzyme that provides the first line of defense against toxic superoxide radicals by catalyzing their dismutation to oxygen and hydrogen peroxide.
V. Ramana Gopavajhula +5 more
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Metalloprotein models: developing catalytic systems
, 2010 Metal–containing proteins are of particular interest: they are responsible for catalysing important biological process, such as photosynthesis, respiration, water oxidation, molecular oxygen reduction and nitrogen fixation.
Faiella, Marina
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Analysis of Various Metalloprotein Stoichiometry’s with Simultaneous PIXE and NRA
, 2015 Approximately one-third of all proteins contain metal cofactors or bind to various metals. Determining the absolute number of metals contained in these proteins has proven to be difficult. We hope to accurately characterize a protein’s stoichiometry with
Diener, Zachary
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