Results 111 to 120 of about 181,236 (248)

Design and characterization of a fluorogenic substrate selectively hydrolyzed by stromelysin 1 (matrix metalloproteinase-3).

, 1994
Hideaki Nagase, Cynthia G. Fields, Gregg B. Fields   +2 more
openalex   +1 more source

Stromal-epithelial interaction mediates steroidal regulation of metalloproteinase expression in human endometrium. [PDF]

, 1994
Kevin G. Osteen, William H. Rodgers, Mireille Gaire, Joel T. Hargrove, Fred Gorstein, Lynn M. Matrisian   +5 more
openalex   +1 more source

Cardiac Slc25a49‐Mediated Energy Reprogramming Governs Doxorubicin‐Induced Cardiomyopathy through the G6P–AP‐1–Sln Axis

Advanced Science, EarlyView.
Doxorubicin‐induced cardiomyopathy involves mitochondrial energy metabolism dysfunction, exacerbated by cardiomyocyte‐specific Slc25a49 deficiency via oxidative phosphorylation (OXPHOS) suppression and glycolysis activation. The Slc25a49–glucose‐6‐phosphate (G6P)–activator protein‐1 (AP‐1) axis drives myocardial injury by upregulating Sln, disrupting ...
Sitong Wan, Jingyi Qi, Yi Xia, Chang Fan, Teng Xu, Xu Zhang, Jiaxin Shi, Chenxuan Wang, Yitong Cheng, Dongyuan Zhang, Rong Liu, Yinhua Zhu, Changchang Cao, Dekui Jin, Peng An, Yongting Luo, Junjie Luo   +16 more
wiley   +1 more source

Cartilage‐Penetrating Framework Nucleic Acid Nanoparticles Ameliorate Osteoarthritis by Promoting Drug Delivery and Chondrocyte Uptake

Advanced Science, EarlyView.
Based on the poor cartilage penetration of tFNA, a novel tFNA‐2WL with excellent cartilage permeability and perfect chondrocyte endocytosis properties is designed and fabricated. As a result, tFNA‐2WL has a nearly seven‐fold increase in the penetration depth into the cartilage, with the same excellent cell entry properties as tFNA.
Kui Huang, Qiumei Li, Huixuan Lin, Qian Shen, Yaping Wu, Taoran Tian, Chuan Ma, Sirong Shi, Jingang Xiao, Yunfeng Lin   +9 more
wiley   +1 more source

GENE EXPRESSIONS OF TYPE IV COLLAGENASE AND TISSUE INHIBITOR OF METALLOPROTEINASES (TIMP) IN HUMAN BLADDER CANCERS

, 1993
Seiichi Naruo, Hiro‐omi Kanayama, Masashi Aki, Susumu Kagawa   +3 more
openalex   +2 more sources

Distinct localization of collagenase and tissue inhibitor of metalloproteinases expression in wound healing associated with ulcerative pyogenic granuloma. [PDF]

, 1992
Ulpu Saarialho‐Kere, Elise S. Chang, Howard G. Welgus, William C. Parks   +3 more
openalex   +1 more source

Highly Stretchable, Self‐Healable, and Conductive Gelatin Methacryloyl Hydrogel for Long‐Lasting Wearable Tactile Sensors

Advanced Science, EarlyView.
Gelatin methacryloyl hydrogel, which possesses high stretchability, tensile strength, toughness, and autonomous self‐healing capability at room temperature, is developed through the introduction of interpenetrating networks, hierarchical hydrogen bonds (weak and strong H‐bonds), and borate ester bonds.
Zhikang Li, Bin Wang, Jijian Lu, Yumeng Xue, Jiaxiang Wang, Boqing Jia, Gengyu Han, Yihe Zhao, Muhammad Afzal Khan Qureshi, Lan Yu, Kang Zhao, Min Li, Ping Yang, Dejiang Lu, Libo Zhao   +14 more
wiley   +1 more source

Distribution of the matrix metalloproteinases stromelysin, gelatinases A and B, and collagenase in Crohn's disease and normal intestine. [PDF]

, 1994
Clifford J. Bailey, Rosalind M. Hembry, A Alexander, M H Irving, Michael E. Grant, C. Adrian Shuttleworth   +5 more
openalex   +1 more source

Fragment Autoantigens Stimulated T‐Cell‐Immunotherapy (FAST) as a Fast Autologous Cancer Vaccine

Advanced Science, EarlyView.
A personalized whole tumor cell vaccine (FAST) is developed to address immunosuppressive tumor microenvironments and genomic instability‐driven heterogeneity. Irradiation and cryoablation‐treated tumor cells generate fragmented antigens (FAs) that activate broad‐spectrum antigen presentation via upregulated immunogenic cell death, MHC‐I, and damage ...
Yuan Li, Huiqin Chen, Qiaofeng Shen, Yingshuang Liu, Pingping Li, Yuqi Ma, Yugang Wang, Shengkai Li, Xueqing Yan, Liyu Liu, Jianwei Shuai, Min Wu, Qi Ouyang, Feng‐Ming (Spring) Kong, Gen Yang   +14 more
wiley   +1 more source

Matrix metalloproteinases degrade insulin-like growth factor-binding protein-3 in dermal fibroblast cultures.

, 1994
John L. Fowlkes, Jan J. Enghild, Ko Suzuki, Hideaki Nagase   +3 more
openalex   +1 more source