Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.Magnetic soft robots offer promise in biomedicine due to their wireless actuation and rapid response, but current fabrication methods are complex and have limited cellular compatibility. A new, contactless bioassembly strategy using hydrodynamic instabilities is introduced, enabling customizable, centimeter‐scale robots.
Wei Gao +5 more
wiley +1 more source
Exploring the causal relationship between matrix metalloproteinases and adrenocortical carcinoma: A Mendelian randomization study. [PDF]
Medicine (Baltimore)Huang Z, Zhang Q.
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Therapy for Myhre Syndrome: Goals, Misconceptions, and Current Agents
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.ABSTRACT Myhre Syndrome (MYHRS, MIM #139210) is a rare, multisystem connective tissue disorder caused by recurrent heterozygous gain‐of‐function pathogenic variants in the SMAD4 gene, a key player in TGF‐β signaling and a regulator of extracellular matrix homeostasis.
Alessandro De Falco +2 more
wiley +1 more source
Proteolytic dysregulation in the skin: insight from rare monogenic skin diseases. [PDF]
Cell Tissue ResLi Z, Wang S, Blaydon DC, Kelsell DP.
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Quantitative proteomics identifies clusterin as a novel biomarker for atherosclerosis
Animal Models and Experimental Medicine, EarlyView.This schematic illustrates the proposed mechanism. In advanced atherosclerotic lesions, upregulated CLU on the cell surface activates low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1). This interaction triggers the phosphorylation and activation of AKT.
Dengfeng Ding +10 more
wiley +1 more source
Cross-Sectional Analysis of Matrix Metalloproteinases and Bone Resorption Regulators in Apical Periodontitis: Linking Molecular Mechanisms with Clinical and Histopathological Features. [PDF]
Acta Stomatol CroatPurešević D +8 more
europepmc +1 more source
Animal Models and Experimental Medicine, EarlyView.In the compression suture group, a 5‐mm‐wide tail skin was removed, and then the defect was sutured to apply compressive force to the intervertebral disc. In the sham group, only the 5‐mm‐wide tail skin was removed without a compression suture. Compression suturing triggers apoptosis, inflammatory response, and imbalance of extracellular matrix ...
Xuening Liu +4 more
wiley +1 more source
The Extracellular Matrix, the Silent 'Architect' of Glioma. [PDF]
BiomedicinesRubio C +5 more
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Metabolic and biochemical profiling reveals phenotypic heterogeneity in Zucker diabetic fatty rats
Animal Models and Experimental Medicine, EarlyView.Genetically uniform Zucker Diabetic Fatty (ZDF) rats spontaneously develop four distinct metabolic phenotypes despite identical housing and diet conditions. Each phenotype exhibits unique biomarker signatures encompassing glucose homeostasis, insulin secretion, polyol pathway activation, oxidative stress, inflammatory cytokines, and neurotrophic ...
Marek Lepáček +3 more
wiley +1 more source
[Expression of Concern] Lentivirus-mediated RNA interference targeting UbcH10 reduces cell growth and invasion of human osteosarcoma cells via inhibition of Ki-67 and matrix metalloproteinases. [PDF]
Oncol LettWang ST +6 more
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