Results 1 to 10 of about 132,850 (336)

Tissue inhibitors of metalloproteinases. [PDF]

Genome Biol, 2011
Orchestration of the growth and remodeling of tissues and responses of cells to their extracellular environment is mediated by metalloproteinases of the Metzincin clan.
Murphy G.
europepmc   +5 more sources

Matrix Metalloproteinases/Tissue Inhibitors of Metalloproteinases Ratio: A Biomarker of Bone Resorption in Geriatric Osteoporosis? [PDF]

Annals of Geriatric Medicine and Research, 2023
Background Matrix metalloproteinases (MMPs) play an important role in bone resorption and are regulated by tissue inhibitors of metalloproteinases (TIMPs).
Bahar Bektan Kanat, Gulru Ulugerger Avci, Osman Faruk Bayramlar, Damla Unal, Ozge Sonmez, Ibrahim Murat Bolayirli, Alper Doventas, Deniz Suna Erdincler, Hakan Yavuzer   +8 more
doaj   +2 more sources

Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in Echinoderms: Structure and Possible Functions [PDF]

Cells, 2021
Echinoderms are one of the most ancient groups of invertebrates. The study of their genomes has made it possible to conclude that these animals have a wide variety of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs ...
Igor Yu. Dolmatov, Vladimir A. Nizhnichenko, Lyudmila S. Dolmatova   +2 more
doaj   +2 more sources

Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases: Structure, Function, and Biochemistry [PDF]

Circulation Research, 2003
Matrix metalloproteinases (MMPs), also designated matrixins, hydrolyze components of the extracellular matrix. These proteinases play a central role in many biological processes, such as embryogenesis, normal tissue remodeling, wound healing, and angiogenesis, and in diseases such as atheroma, arthritis, cancer, and tissue ulceration.
R. Visse, Hideaki Nagase
semanticscholar   +3 more sources

Tissue inhibitors of metalloproteinases are proteolytic targets of matrix metalloproteinase 9. [PDF]

Matrix Biol, 2023
Extracellular proteolysis and turnover are core processes of tissue homeostasis. The predominant matrix-degrading enzymes are members of the Matrix Metalloproteinase (MMP) family. MMPs extensively degrade core matrix components in addition to processing a range of other factors in the extracellular, plasma membrane, and intracellular compartments.
Coates-Park S, Lazaroff C, Gurung S, Rich J, Colladay A, O'Neill M, Butler GS, Overall CM, Stetler-Stevenson WG, Peeney D.   +9 more
europepmc   +3 more sources

The Role of Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in Duchenne Muscular Dystrophy Cardiomyopathy. [PDF]

J Card Fail, 2019
BACKGROUND Cardiomyopathy is the leading cause of death in Duchenne muscular dystrophy (DMD). Standard cardiac biomarkers are poor indicators of DMD cardiovascular disease.
Soslow JH, Xu M, Slaughter JC, Crum K, Chew JD, Burnette WB, Su YR, Tomasek K, Parra DA, Markham LW.   +9 more
europepmc   +2 more sources

Effect of anti-tuberculosis treatment on the systemic levels of tissue inhibitors of metalloproteinases in tuberculosis – Diabetes co-morbidity [PDF]

Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, 2021
Objectives: To study the association of Tissue inhibitors of matrix metalloproteinases (TIMP) levels with tuberculosis-diabetes comorbidity (TB-DM) comorbidity at baseline and in response to anti-TB treatment (ATT).
Nathella Pavan Kumar, Kadar Moideen, Vijay Viswanathan, Shanmugam Sivakumar, Syed Hissar, Hardy Kornfeld, Subash Babu   +6 more
doaj   +2 more sources

Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases Are Potential Biomarkers of Pulmonary and Extra-Pulmonary Tuberculosis [PDF]

Frontiers in Immunology, 2020
Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinase (TIMPs) are potential regulators of tuberculosis (TB) pathology. Whether they are candidates for non-sputum-based biomarkers for pulmonary TB (PTB) and extra-pulmonary TB (EPTB ...
Gokul Raj Kathamuthu, Gokul Raj Kathamuthu, Nathella Pavan Kumar, Kadar Moideen, Dina Nair, Vaithilingam V. Banurekha, Rathinam Sridhar, Dhanaraj Baskaran, Subash Babu, Subash Babu   +9 more
doaj   +2 more sources

Clinical Investigation of Matrix Metalloproteinases, Tissue Inhibitors of Matrix Metalloproteinases, and Matrix Metalloproteinase/Tissue Inhibitors of Matrix Metalloproteinase Complexes and Their Networks in Apical Periodontitis. [PDF]

Journal of Endodontics, 2016
This clinical study investigated the levels of metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) and respective forms (MMP/TIMP complexes) in apical periodontitis to determine their networks in the development of clinical/radiographic features, thus quantifying the levels of endotoxins (lipopolysaccharides) present in primarily infected ...
F. Martinho, F. F. C. Teixeira, F. G. Cardoso, N. S. Ferreira, G. G. Nascimento, C. Carvalho, M. Valera   +6 more
semanticscholar   +4 more sources

Expression of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in renal cell carcinoma

World Journal of Surgical Oncology, 2013
Background Matrix metalloproteinases (MMPs) are one of the major classes of proteolytic enzymes involved in tumor invasion and metastasis and are inhibited by naturally occurring tissue inhibitors of metalloproteinases (TIMPs).
Qiao Zhen-kui, Li Yan-long, Lu Hong-tao, Wang Ke-liang, Xu Wan-hai   +4 more
doaj   +2 more sources