Results 1 to 10 of about 166,023,390 (251)
Cells, 2021 Echinoderms are one of the most ancient groups of invertebrates. The study of their genomes has made it possible to conclude that these animals have a wide variety of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs ...
Igor Yu. Dolmatov +2 more
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Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases [PDF]
Circulation Research, 2003 Matrix metalloproteinases (MMPs), also designated matrixins, hydrolyze components of the extracellular matrix. These proteinases play a central role in many biological processes, such as embryogenesis, normal tissue remodeling, wound healing, and angiogenesis, and in diseases such as atheroma, arthritis, cancer, and tissue ulceration.
Visse, R, Nagase, H
openaire +3 more sources
Metalloproteinases and Their Inhibitors: Potential for the Development of New Therapeutics
Cells, 2020 The metalloproteinase (MP) family of zinc-dependent proteases, including matrix metalloproteinases (MMPs), a disintegrin and metalloproteases (ADAMs), and a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTSs) plays a crucial role in ...
Maryam Raeeszadeh-Sarmazdeh +2 more
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Circulating Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in Cardiac Amyloidosis [PDF]
Journal of the American Heart Association, 2013 Background Cardiac amyloidosis due to amyloid fibril deposition in the heart results in cardiomyopathy ( CMP ) with heart failure ( HF ) and/or conduction disturbances. Immunoglobulin light chain–related CMP ( AL
Flora Sam +2 more
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Matrix Metalloproteinases/Tissue Inhibitors of Metalloproteinases Ratio: A Biomarker of Bone Resorption in Geriatric Osteoporosis? [PDF]
Annals of Geriatric Medicine and Research, 2023 Background Matrix metalloproteinases (MMPs) play an important role in bone resorption and are regulated by tissue inhibitors of metalloproteinases (TIMPs).
Bahar Bektan Kanat +8 more
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Expression of Matrix Metalloproteinase-2/9 and Tissue Inhibitor of Metalloproteinase-1/2 as Predictive Factors in Oropharyngeal Squamous Cell Carcinoma [PDF]
Iranian Journal of Otorhinolaryngology, 2019 Introduction: Metalloproteinases and their tissue inhibitors play an important role in the metastases formation. A multistage process of carcinogenesis requires the involvement of numerous enzymes and compounds that facilitate the expansion of tumor ...
Pawel Burduk +4 more
doaj +1 more source
Frontiers in Physiology, 2021 Systemic sclerosis (SSc) is a chronic debilitating idiopathic disorder, characterized by deposition of excessive extracellular matrix (ECM) proteins such as collagen which leads to fibrosis of the skin and other internal organs.
Edwin Leong +4 more
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Time-dependent matrix metalloproteinases and tissue inhibitor of metalloproteinases expression change in fusarium solani keratitis [PDF]
International Journal of Ophthalmology, 2016 AIM: To investigate matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinases (TIMPs) expression during the progress of fusarium solani (F.solani) keratitis in a rat model.
Qian Li +5 more
doaj +1 more source
Кардиоваскулярная терапия и профилактика, 2022 Aim. To compare the effect of atorvastatin and rosuvastatin as part of complex therapy in patients with hypertension (HTN) with a high cardiovascular risk on the level of matrix metalloproteinases -1, -9 (MMP-1, MMP-9) and tissue inhibitors of ...
V. P. Mikhin +4 more
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BMC Research Notes, 2021 Objective Matrix metalloproteinases (MMPs) are important regulators of vascular and uterine remodeling. They exhibit proteolytic activity implicating the efficiency of trophoblast invasion to the uterine wall involving marked hemodynamic and uterine ...
Ritva Nissi +2 more
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