Results 31 to 40 of about 166,023,390 (251)

Promoter variants in tissue inhibitor of metalloproteinase-3 (TIMP-3) protect against susceptibility in pigeon breeders' disease. [PDF]

, 2004
BACKGROUND: Tissue inhibitors of metalloproteinases (TIMPs) play a major role in extracellular matrix turnover in the lung. However, in chronic lung disorders such as idiopathic pulmonary fibrosis (IPF) and pigeon breeders' disease (PBD), TIMPs may ...
Briggs, L, Montaño, MM, Pardo, A, Estrada, A, Laurent, GJ, Selman, M, Hill, MR, Pardo-Cemo, Annie   +7 more
core   +1 more source

Induced sputum MMP-1, -3 & -8 concentrations during treatment of tuberculosis. [PDF]

, 2013
INTRODUCTION: Tuberculosis (TB) destroys lung tissues and this immunopathology is mediated in part by Matrix Metalloproteinases (MMPs). There are no data on the relationship between local tissue MMPs concentrations, anti-tuberculosis therapy and sputum ...
Jorge Coronel, Friedland, Jon S, Bernabe-Ortiz, A., Coronel, Jorge, Gotuzzo, E., Gotuzzo Eduardo, Antonio Bernabe-Ortiz, Moore, David AJ, Ugarte-Gil, C.A., Coronel Jorge, Elkington, P.T., Moore, D.A.J., Eduardo Gotuzzo, Coronel, J., Paul Elkington, Robert H Gilman, Moore David A. J., Friedland, J.S., Gilman, R., Elkington Paul, Ugarte-Gil, Cesar A, Bernabe-Ortiz Antonio, Gilman Robert H., Cesar A Ugarte-Gil, Friedland Jon S., Elkington, Paul, Jon S Friedland, Gotuzzo, Eduardo, David A J Moore, Ugarte-Gil Cesar A., Tezera, Liku B, Gilman, Robert H, Liku B Tezera, Tezera Liku B., Bernabe-Ortiz, Antonio   +34 more
core   +1 more source

The possibilities of using the inhibitors of matrix metalloproteinases for keratoplasty

Трансплантология (Москва), 2023
Introduction. The review is devoted to the actual problem of treating patients with keratolysis. The role of matrix metalloproteinases in the pathogenesis of cornea and corneal graft melting is discussed as well as the practical experience of using ...
K. V. Sirotkina, E. V. Chentsova
doaj   +1 more source

Matrix metalloproteinases at key junctions in the pathomechanism of stroke [PDF]

, 2011
Matrix metalloproteinases play a crucial role in the remodelling of the extracellular matrix through direct degradation of its structural proteins and control of extracellular signaling.
Kolev, Kraszimir, Kolev Krasimir, Rottenberger Zsolt, Zsolt Rottenberger, Rottenberger, Zsolt, Krasimir Kolev   +5 more
core   +1 more source

Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases Are Potential Biomarkers of Pulmonary and Extra-Pulmonary Tuberculosis

Frontiers in Immunology, 2020
Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinase (TIMPs) are potential regulators of tuberculosis (TB) pathology. Whether they are candidates for non-sputum-based biomarkers for pulmonary TB (PTB) and extra-pulmonary TB (EPTB ...
Gokul Raj Kathamuthu, Gokul Raj Kathamuthu, Nathella Pavan Kumar, Kadar Moideen, Dina Nair, Vaithilingam V. Banurekha, Rathinam Sridhar, Dhanaraj Baskaran, Subash Babu, Subash Babu   +9 more
doaj   +1 more source

Biochemical markers assessing rate of reparative processes in patients with infiltrative pulmonary tuberculosis

Инфекция и иммунитет, 2023
Theeffectiveness of chemotherapy for infiltrative pulmonary tuberculosis (ITL) is determined by proper timing and adequacy of treatment. The speed of reparative changes in the pulmonary parenchyma is associated with the effectiveness of therapy ...
Dilyara S. Esmedlyaeva, Nina P. Alekseeva, Marina E. Dyakova   +2 more
doaj   +1 more source

Human keratinocyte cell lines differ in the expression of the collagenolytic matrix metalloproteinases-1,-8, and-13 and of TIMP-1 [PDF]

, 2000
Bachmeier BE, Nerlich AG, Boukamp P, et al. Human keratinocyte cell lines differ in the expression of the collagenolytic matrix metalloproteinases-1,-8, and-13 and of TIMP-1. BIOLOGICAL CHEMISTRY.
Boukamp, P, Tschesche, Harald, Bachmeier, BE, Bachmeier, B. E., Nerlich, A. G., Fink, E., Fritz, H, Fink, E, Fritz, H., Tschesche, H., Lichtinghagen, R., Nerlich, AG, Lichtinghagen, R, Boukamp, P.   +13 more
core   +1 more source

Tissue Localization and Extracellular Matrix Degradation by PI, PII and PIII Snake Venom Metalloproteinases: Clues on the Mechanisms of Venom-Induced Hemorrhage [PDF]

, 2015
20 páginas, 4 figuras, 3 tablas y 7 tablas en material suplementario.Snake venom hemorrhagic metalloproteinases (SVMPs) of the PI, PII and PIII classes were compared in terms of tissue localization and their ability to hydrolyze basement membrane ...
Calvete, JJ, Rucavado Romero, Alexandra, Rucavado, A, Cristina Herrera (576490), Jéssica Kele A. Macêdo (729670), Morazan, D, Diego Morazán (729669), Mathieu-Benoit Voisin (729668), Escalante, Teresa, Libia Sanz, Mathieu-Benoit Voisin, Alexandra Rucavado (32147), Herrera, C, Macêdo, Jéssica Kele A., Jéssica Kele A Macêdo, Teresa Escalante, Calvete Chornet, Juan José, Nourshargh, S, Diego Morazán, Cristina Herrera, Voisin, Mathieu-Benoit, Voisin, M-B, Maria Gutierrez, J, Rucavado, Alexandra, Jay W Fox, José María Gutiérrez, Alexandra Rucavado, Macedo, JKA, Libia Sanz (144843), Juan J. Calvete (144840), Sanz, L, Juan J Calvete, Sussan Nourshargh (157725), Sanz, Libia, Morazán, Diego, Nourshargh, Sussan, Jay W. Fox (164576), Escalante, T, Teresa Escalante (337914), Herrera, Cristina, Calvete, Juan J., Sussan Nourshargh, José María Gutiérrez (62868), Escalante Muñoz, Teresa, Herrera Arias, Cristina, Fox, JW, Fox, Jay W., Gutiérrez, José María   +47 more
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Designing TIMP (tissue inhibitor of metalloproteinases) variants that are selective metalloproteinase inhibitors

Biochemical Society Symposia, 2003
The tissue inhibitors of metalloproteinases (TIMPs) are endogenous inhibitors of the matrix metalloproteinases (MMPs), enzymes that play central roles in the degradation of extracellular matrix components. The balance between MMPs and TIMPs is important in the maintenance of tissues, and its disruption affects tissue homoeostasis.
Nagase, H, Brew, K
openaire   +3 more sources

Chemokine-induced secretion of gelatinase B in primary human monocytes [PDF]

, 2001
Chemokines help control normal leukocyte trafficking as well as their infiltration into tissues during acute and chronic inflammation. Matrix metalloproteinases (MMPs) help support the extravasation and infiltration of leukocytes through limited ...
Nelson, EL, Nelson, P. J., Schlöndorff, D, C.D. Cohen, D. Schlöndorff, C.M. Klier, Horuk, R, P.J. Nelson, Schlöndorff, D., Klier, C. M., E.L. Nelson, Nelson, PJ, Cohen, CD, Horuk, R., Cohen, C. D., R. Horuk, Klier, CM, Nelson, E. L.   +17 more
core   +1 more source