Results 21 to 30 of about 166,023,390 (251)

Galectin-3, metalloproteinase-2 and cardiovascular disease were independently associated with metalloproteinase-14 in patients with type 1 diabetes: a cross sectional study

Diabetology & Metabolic Syndrome, 2021
Background Type 1 diabetes (T1D) is a major risk factor for cardiovascular disease (CVD). Matrix metalloproteinase-14 (MMP-14) is involved in the development of atherosclerosis and CVD.
Eva Olga Melin, Jonatan Dereke, Magnus Hillman   +2 more
doaj   +1 more source

Engineered Sarafotoxins as Tissue Inhibitor of Metalloproteinases-like Matrix Metalloproteinase Inhibitors [PDF]

Journal of Biological Chemistry, 2007
The sarafotoxins and endothelins are approximately 25-residue peptides that spontaneously fold into a defined tertiary structure with specific pairing of four cysteines into two disulfide bonds. Their structures show an interesting topological similarity to the core of the metalloproteinase interaction sites of the tissue inhibitors of ...
Janelle L, Lauer-Fields, Mare, Cudic, Shuo, Wei, Frank, Mari, Gregg B, Fields, Keith, Brew   +5 more
openaire   +2 more sources

Novel bi- and trifunctional inhibitors of tumor-associated proteolytic systems [PDF]

, 2003
Serine proteases, cysteine proteases, and matrix metalloproteinases (MMPs) are involved in cancer cell invasion and metastasis. Recently, a recombinant bifunctional inhibitor (chCysuPA(19-31)) directed against cysteine proteases and the urokinasetype ...
Sato, Sumito, Assfalg-Machleidt, Irmgard, Magdolen, Ulla, Schmitt, Manfred, Rettenberger, Peter, Magdolen, Viktor, Krol, Janna   +6 more
core   +1 more source

Features of the level of matrix metalloproteinase-2, -3, -9 and tissue inhibitors of metalloproteinases-1, -2, -3, -4 in the aqueous humor of patients with primary open-angle glaucoma

Бюллетень сибирской медицины, 2022
Aim. To study the content of matrix metalloproteinase (MMP)-2, -3, -9 and tissue inhibitors of metalloproteinases (TIMPs) -1, -2, -3, -4 in the aqueous humor of patients with moderate primary open-angle glaucoma (POAG).Materials and methods.
V. V. Chernykh, V. I. Konenkov, O. V. Ermakova, N. B. Orlov, A. N. Trunov   +4 more
doaj   +1 more source

Recombinant GPI-anchored TIMP-1 stimulates growth and migration of peritoneal mesothelial cells. [PDF]

, 2012
Mesothelial cells are critical in the pathogenesis of post-surgical intraabdominal adhesions as well as in the deterioration of the peritoneal membrane associated with long-term peritoneal dialysis.
Elfriede Noessner, Susan Notohamiprodjo, Pankaj Goyal, Sauter, M., Sitter, T., Sitter, Thomas, Markus Wörnle, Andrea Ribeiro, Peter J. Nelson (168215), Thomas Sitter, Matthias Sauter (168187), Wolfgang Siess, Wolfgang Siess (168198), Susanne Himmelein, Nelson, P.J., Himmelein, Susanne, Thomas Sitter (168211), Goyal, P., Sauter, Matthias, Susanne Himmelein (168206), Nelson, Peter J., Markus Wörnle (168201), Susan Notohamiprodjo (168192), Ribeiro, A., Notohamiprodjo, Susan, Elfriede Noessner (146689), Noessner, Elfriede, Wörnle, Markus, Djafarzadeh, Roghieh, Roghieh Djafarzadeh, Matthias Sauter, Nößner, E., Andrea Ribeiro (168203), Roghieh Djafarzadeh (88033), Himmelein, S., Peter J Nelson, Wörnle, M., Goyal, Pankaj, Ribeiro, Andrea, Djafarzadeh, R., Notohamiprodjo, S., Pankaj Goyal (156516), Siess, W., Siess, Wolfgang   +43 more
core   +2 more sources

Plasma matrix metalloproteinases in neonates having surgery for congenital heart disease

Heart International, 2009
During cardiopulmonary-bypass matrix-metalloproteinases released may contribute to ventricular dysfunction. This study was to determine plasma matrix-metalloproteinases in neonates after cardiopulmonary-bypass and their relation to post-operative course.
David B. Ross, Richard Schulz, Po-Yin Cheung, Ivan M. Rebeyka, Rhonda J. Rosychuk, John Dyck, Ari R. Joffe, Christina Schulz   +7 more
doaj   +1 more source

Effect of anti-tuberculosis treatment on the systemic levels of tissue inhibitors of metalloproteinases in tuberculosis – Diabetes co-morbidity

Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, 2021
Objectives: To study the association of Tissue inhibitors of matrix metalloproteinases (TIMP) levels with tuberculosis-diabetes comorbidity (TB-DM) comorbidity at baseline and in response to anti-TB treatment (ATT).
Nathella Pavan Kumar, Kadar Moideen, Vijay Viswanathan, Shanmugam Sivakumar, Syed Hissar, Hardy Kornfeld, Subash Babu   +6 more
doaj   +1 more source

Activity of matrix metalloproteinases and their tissue inhibitors in serum in chronic granulating periodontitis

Patologìâ, 2019
Aim. The aim of the work is to study the activity of matrix metalloproteinases and their tissue inhibitors in chronic granular periodontitis. Materials and methods. We examined serum of 15 patients with chronic granulating periodontitis and 15 healthy
D. I. Haidash, I. S. Haidash, O. О. Bondar, Yu. О. Yevtushenko, O. I. Haidash   +4 more
doaj   +1 more source

Inactivation of tissue inhibitor of metalloproteinase‐1 by peroxynitrite [PDF]

FEBS Letters, 1996
Peroxynitrate (ONOO−) has recently been implicated in connective tissue destruction in vivo. We have studied the effect of ONOO− on the activity of tissue inhibitor of metalloproteinase‐1 (TIMP‐1) in vitro. The inactivation of TIMP‐1 by ONOO− was dose dependent with 50 μM ONOO− reducing the inhibitory activity of TIMP‐1 towards gelatinase‐A by 50 ...
Frears, Emma R., Zhang, Zhi, Blake, David R., O'Connell, James P., Winyard, Paul G.   +4 more
openaire   +2 more sources

Dependence of TIMP-1 plasma levels on preanalytical specimen handling [PDF]

, 2008
Background: Tissue inhibitor of metalloproteinases-1 (TIMP-1) in blood might be a helpful biomarker in various diseases. However, various authors report that TIMP-1 is dependent on preanalytical procedures.
Doss, Robert, Dorothea Nagel, Barry Dowell, Stieber, Petra, Marie Dresse, Dowell, Barry, Dresse, Marie, Robert Doss, Davis, Gerard, Ganser, Eva-Maria, Gerard Davis, Eva-Maria Ganser, Nagel, Dorothea, Petra Stieber   +13 more
core   +1 more source