Results 1 to 10 of about 156,368 (309)
OVEREXPRESSION/KNOCKDOWN OF ADAPTOR PROTEIN Ruk/CIN85 IN HUMAN LUNG ADENOCARCINOMA A549 CELLS RESULTS IN OPPOSITE CHANGES BETWEEN MMP-2/MMP-9 EXPRESSION LEVELS/ACTIVITIES AND CELL`S INVASION [PDF]
Biotechnologia Acta, 2023 Aim. To investigate the changes in MMPs expression and activity as well as invasiveness of human lung adenocarcinoma A549 cells with up-/down-regulation of Ruk/CIN85. Methods.
M.I. BEKALA +3 more
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COL12A1-rs970547, Mutant Allele Advantage by Being Protective against Recurrent Spontaneous Abortion [PDF]
Journal of Genetic Resources, 2023 Recurrent spontaneous abortion (RSA) is one of the causes of infertility following fetus creation. This can lead to the reduction of the fertility rate in various populations.
Abasalt Hosseinzadeh Colagar +3 more
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Functional polymorphisms in the promoters of MMP-1, MMP-2, MMP-3, MMP-9, MMP-12 and MMP-13 are not associated with hepatocellular carcinoma risk [PDF]
Gut, 2007 The matrix metalloproteinases (MMPs) play an important role in several steps of cancer development by regulating cancer-cell growth, differentiation, apoptosis, invasion, metastasis, angiogenesis and immune surveillance.1 Several polymorphisms in the promoters of a number of MMP genes, which are thought to affect the respective MMP production in an ...
Yun, Zhai +8 more
openaire +2 more sources
Zhongguo shuxue zazhi, 2023 Objective To compare the bioactive ingredients in activated platelet-rich plasma (PRP) from cord blood and adult blood, explore its reasonable indicators reflecting the inflammatory regulation ability, in order to guide the preparation.
Bingzheng MA +7 more
doaj +1 more source
Journal of Investigative Surgery, 2022 Objective We investigated the serum levels of MMPs and TIMPs in breast cancer (BC) patients to predict the response rate to/after treatment with or without neoadjuvant chemotherapy.
Kayhan Ozdemir +6 more
doaj +1 more source
Jujube and green tea extracts protect human fibroblast cells against UVB-mediated photo damage and MMP-2 and MMP-9 production [PDF]
Avicenna Journal of Phytomedicine, 2020 Objective: Oxidative stress and ultraviolet B (UVB) irradiation are known as principal inducers of DNA damage and modulators of gene expression in aging process and skin photoaging, which are associated with upregulation of matrix metalloproteinases ...
Zahra Abotorabi +4 more
doaj +1 more source
Current Issues in Pharmacy and Medical Sciences, 2020 Bladder cancer (BC) is a worldwide common disease with a high mortality rate. Recognizing the dynamic changes in plasma that proteases and their inhibitors undergo might be valuable in understanding the carcinogenesis of invasive bladder cancer and in ...
Dmytryk Viktor +6 more
doaj +1 more source
Biomolecules, 2020 Background: Matrix metalloproteinases (MMPs) are involved in vascular wall degradation, and drugs able to modulate MMP activity can be used to prevent or treat aneurysmal disease.
Erika Cione +11 more
doaj +1 more source
Current Issues in Pharmacy and Medical Sciences, 2023 Diabetes patients are more prone to acute kidney injury (AKI). Endopeptidases known as matrix metalloproteinases (MMPs) cause extracellular matrix destruction and are responsible for ischemic organ damage.
Daude Rakesh B., Shah Jigna S.
doaj +1 more source
Distinct emphysema subtypes defined by quantitative CT analysis are associated with specific pulmonary matrix metalloproteinases. [PDF]
, 2016 BACKGROUND: Emphysema is characterised by distinct pathological sub-types, but little is known about the divergent underlying aetiology. Matrix-metalloproteinases (MMPs) are proteolytic enzymes that can degrade the extracellular matrix and have been ...
Bourne, S +10 more
core +1 more source