Results 11 to 20 of about 246,934 (340)
MMPs and ADAMs in neurological infectious diseases and multiple sclerosis [PDF]
Cellular and Molecular Life Sciences, 2019 Metalloproteinases—such as matrix metalloproteinases (MMPs) and a disintegrin and metalloproteinases (ADAMs)—are involved in various diseases of the nervous system but also contribute to nervous system development, synaptic plasticity and ...
Lukas Muri +3 more
semanticscholar +4 more sources
Kidney Fibrosis and Matrix Metalloproteinases (MMPs).
Frontiers in BioscienceChronic kidney disease (CKD) is a disorder that causes changes in both the structure and function of the kidneys, causing complications such as hypertension, edema, and oliguria. Renal fibrosis is also a common pathological feature of CKD.
A. La Russa +11 more
semanticscholar +2 more sources
Functional polymorphisms in the promoters of MMP-1, MMP-2, MMP-3, MMP-9, MMP-12 and MMP-13 are not associated with hepatocellular carcinoma risk [PDF]
Gut, 2007 The matrix metalloproteinases (MMPs) play an important role in several steps of cancer development by regulating cancer-cell growth, differentiation, apoptosis, invasion, metastasis, angiogenesis and immune surveillance.1 Several polymorphisms in the promoters of a number of MMP genes, which are thought to affect the respective MMP production in an ...
Yun, Zhai +8 more
openaire +2 more sources
Journal of Investigative Surgery, 2022 Objective We investigated the serum levels of MMPs and TIMPs in breast cancer (BC) patients to predict the response rate to/after treatment with or without neoadjuvant chemotherapy.
Kayhan Ozdemir +6 more
doaj +1 more source
Zhongguo shuxue zazhi, 2023 Objective To compare the bioactive ingredients in activated platelet-rich plasma (PRP) from cord blood and adult blood, explore its reasonable indicators reflecting the inflammatory regulation ability, in order to guide the preparation.
Bingzheng MA +7 more
doaj +1 more source
Biomolecules, 2020 Background: Matrix metalloproteinases (MMPs) are involved in vascular wall degradation, and drugs able to modulate MMP activity can be used to prevent or treat aneurysmal disease.
Erika Cione +11 more
doaj +1 more source
Jujube and green tea extracts protect human fibroblast cells against UVB-mediated photo damage and MMP-2 and MMP-9 production [PDF]
Avicenna Journal of Phytomedicine, 2020 Objective: Oxidative stress and ultraviolet B (UVB) irradiation are known as principal inducers of DNA damage and modulators of gene expression in aging process and skin photoaging, which are associated with upregulation of matrix metalloproteinases ...
Zahra Abotorabi +4 more
doaj +1 more source
Emerging roles of MT-MMPs in embryonic development
, 2021 Membrane-type matrix metalloproteinases (MT-MMPs) are cell membranetethered proteinases that belong to the family of the MMPs. Apart from their roles in degradation of the extracellular milieu, MT-MMPs are able to activate through proteolytic processing ...
Muñoz Sáez, Emma +23 more
core +1 more source
MMPs and ADAMs/ADAMTS Inhibition Therapy of Abdominal Aortic Aneurysm
Life Science, 2020 Abdominal aortic aneurysm (AAA) is a chronic vascular degenerative disease featured by progressive dilation and remodeling of the vascular wall, which may lead to aortic rupture and high mortality.
Yongqi Li +3 more
semanticscholar +1 more source
Sodium Fluoride Inhibits MMP-2 and MMP-9 [PDF]
Journal of Dental Research, 2013 The importance of fluoride (F) in preventing dental caries by favorably interfering in the demineralization-remineralization processes is well-established, but its ability to inhibit matrix metalloproteinases (MMPs), which could also help to prevent dentin caries, has not been investigated.
Kato, MT +5 more
openaire +2 more sources