Results 131 to 140 of about 9,173 (177)
Some of the next articles are maybe not open access.
Current Opinion in Biotechnology, 1996
The rational design of novel proteins offers a new method of studying structure and function, and makes possible the construction of new biomaterials. The richness of metal chemistry, the relative ease of creating stable complexes, and the remarkable degree of subtle, highly specific control of reactivity imposed by the protein matrix upon the metal ...
openaire +2 more sources
The rational design of novel proteins offers a new method of studying structure and function, and makes possible the construction of new biomaterials. The richness of metal chemistry, the relative ease of creating stable complexes, and the remarkable degree of subtle, highly specific control of reactivity imposed by the protein matrix upon the metal ...
openaire +2 more sources
NMR Spectroscopy of Paramagnetic Metalloproteins
ChemBioChem, 2005AbstractThis article deals with the solution structure determination of paramagnetic metalloproteins by NMR spectroscopy. These proteins were believed not to be suitable for NMR investigations for structure determination until a decade ago, but eventually novel experiments and software protocols were developed, with the aim of making the approach ...
Roberta Pierattelli +2 more
exaly +4 more sources
Predicting cracks in metalloproteins
Nature Machine Intelligence, 2019Loss-of-function mutations in metal-binding proteins are heavily implicated with numerous diseases, and identifying such ‘cracks’ will be valuable to biologists and medical doctors in the study and treatment of disease. A deep learning approach has been developed to tackle this challenging task.
Yuan Liu, Chu Wang
openaire +1 more source
Computational Design of Metalloproteins
2014A number of design strategies exist for the development of novel metalloproteins. These strategies often exploit the inherent symmetry of metal coordination and local topology. Computational design of metal binding sites in flexible regions of proteins is challenging as the number of conformational degrees of freedom is significantly increased ...
Avanish S, Parmar +2 more
openaire +2 more sources
Metalloproteins and metal sensing
Nature, 2009Almost half of all enzymes must associate with a particular metal to function. An ambition is to understand why each metal-protein partnership arose and how it is maintained. Metal availability provides part of the explanation, and has changed over geological time and varies between habitats but is held within vital limits in cells.
Kevin J, Waldron +3 more
openaire +2 more sources
Metalloproteins in the evolution of photosynthesis
Biosystems, 1981Certain metalloproteins are common to all photosynthetic electron transfer chains. These include soluble proteins such as ferredoxins and cytochromes of the c2 type, and membrane-bound components such as cytochrome b, c1 and the Rieske iron-sulphur protein.
R, Cammack, K K, Rao, D O, Hall
openaire +2 more sources
2015
Preface: Metalloproteins play essential critical functional roles in enzymatically catalyzing reactions difficult to achieve without metals, in signal transduction, and in storage and transport of proteins constituting over 1/3 of the proteome of living organisms.
openaire +1 more source
Preface: Metalloproteins play essential critical functional roles in enzymatically catalyzing reactions difficult to achieve without metals, in signal transduction, and in storage and transport of proteins constituting over 1/3 of the proteome of living organisms.
openaire +1 more source
A supramolecular assembly enables discrimination between metalloproteins and non-metalloproteins
Chemical Communications, 2018A supramolecular assembly yields turn-on fluorescence response for non-metalloproteins and turn-off response for metalloproteins.
Aafrin M, Pettiwala, Prabhat K, Singh
openaire +2 more sources
EXAFS: a probe for metalloproteins
Nature, 1990X-ray absorption spectroscopy provides a method for studying the local environment around a metal atom in a protein.
openaire +2 more sources
Metalloproteins and neuronal death
Metallomics, 2010Neurodegenerative diseases include Alzheimer's and Parkinson's disease that are very common and other diseases that are notorious but occur less often such as Creutzfeldt-Jakob disease. In each case a protein is closely linked to the pathology of these diseases. These proteins include alpha-synuclein, the prion protein and Aβ.
openaire +2 more sources