Results 161 to 170 of about 27,575 (332)

Designing Enzymatic Reactivity with an Expanded Palette

open access: yesChemBioChem, Volume 26, Issue 11, June 3, 2025.
Innovation in biocatalysis is rapidly increasingly the diversity of catalytic reactivity that can be mediated by enzymes, addressing a key bottleneck for their widespread adoption in industrial chemical synthesis. A key approach to this is building enzymes with unnatural catalytic components that provide an expanded palette with new possibilities for ...
Reuben B. Leveson‐Gower
wiley   +1 more source

De Novo Engineering of Solid-State Metalloproteins Using Recombinant Coiled-Coil Silk.

open access: yesACS Biomaterials Science & Engineering, 2015
To achieve the sophisticated chemistry required for life, nature uses metal containing proteins (metalloproteins). However, despite intensive research efforts, very few of these metalloproteins have been exploited for biotechnological applications.
Trevor D. Rapson   +5 more
semanticscholar   +1 more source

Moisturizing Treatment Outcomes: A Comparative Study of Diabetic and Nondiabetic Skin, Associated With the Presence or Absence of Dermatoporosis

open access: yesDermatological Reviews, Volume 6, Issue 3, June 2025.
ABSTRACT Background Skin disorders are highly common in type 1 and 2 diabetes mellitus patients. This study assessed the effects of a moisturizing formulation on photoprotected (volar forearm) and photoexposed (dorsal hand) skin in diabetic and nondiabetic participants, with or without stage I dermatoporosis, comparing it to a reference product ...
Juliana Rodrigues Pinto   +2 more
wiley   +1 more source

Structurally and Functionally Adaptive Biomimetic Periosteum: Materials, Fabrication, and Construction Strategies

open access: yesExploration, Volume 5, Issue 3, June 2025.
Schematic illustration of structural and functional biomimicry. The upper part shows BP with various structures such as monolayered, surface‐microstructural, bilayered and multilayered. The bottom part exhibits BP with different functions including immune regulation, drugs/cells/factors/ions loading, as well as bioelectrical stimulation and ...
Yuhan Du   +7 more
wiley   +1 more source

Modification of Aminoacyl tRNA Synthetase in Order to Incorporate an Unnatural Amino Acid [PDF]

open access: yes, 2018
Proteins allow daily processes in the cell to occur. A protein consists of amino acids. There are twenty natural amino acids coded for in the DNA of organisms. The natural amino acids can be modified to form unnatural amino acids (UAAs). UAAs have useful
Burkhart, Grace
core   +1 more source

The in crystallo optical spectroscopy toolbox

open access: yesJournal of Applied Crystallography, Volume 58, Issue 3, Page 1068-1078, June 2025.
The rise of time‐resolved macromolecular crystallography has been accompanied by renewed interest in companion biophysical characterization methods applicable to molecules both in solution and in crystallo. Here, we present a workflow and a graphical interface for analysing spectroscopic data collected on macromolecular crystals.Over the past ten years,
Nicolas Caramello   +3 more
wiley   +1 more source

Dynamic quantum sensing of paramagnetic species using nitrogen-vacancy centers in diamond [PDF]

open access: yesarXiv, 2019
Naturally occurring paramagnetic species (PS), such as free radicals and paramagnetic metalloproteins, play an essential role in a multitude of critical physiological processes including metabolism, cell signaling and immune response. These highly dynamic species can also act as intrinsic biomarkers for a variety of disease states whilst synthetic para-
arxiv  

Electrode Nanopatterning for Bioelectroanalysis and Bioelectrocatalysis

open access: yesElectrochemistry
Although intensive research in the bioelectroanalysis domain in the last twenty years led to great improvements in protein-based electrode and device performances, their large application remains limited by their stability overtime under operational and ...
Umberto CONTALDO   +3 more
doaj   +1 more source

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