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Metamizol-induzierte akute Agranulozytose
Gastroenterologie up2date, 2010Jens Standop, Jörg Kalff
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Pharmacokinetics of metamizol metabolites.
Agents and actions. Supplements, 1986When administered to humans, metamizol rapidly undergoes predominantly nonenzymatic biotransformation, yielding a vast number of active and later inactive metabolites. The biotransformational pathways and the clinical significance of the metabolites are discussed in the light of their individual pharmacokinetics.
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