Results 1 to 10 of about 6,507 (223)

Antipyretic effect of oral dipyrone (Metamizole) compared to oral ibuprofen in febrile children: a systematic review and meta-analysis [PDF]

BMC Pediatrics
Background Dipyrone (Metamizole) is a potent pain reliever and fever reducer with muscle relaxant properties, most commonly used as an analgesic and antipyretic agent.
Maged Alnajar, Zahraa Saker, Fatma Haji, Menna A Abdelsamed, Zeinab Khaled, Mohamed Abd-ElGawad   +5 more
doaj   +4 more sources

The antipyretic effectiveness of dipyrone in the intensive care unit: A retrospective cohort study.

PLoS ONE, 2022
IntroductionDipyrone (metamizol) is regularly used in critical care for pain and fever treatment, especially in Germany and Spain. However, indication for antipyretic therapy in critically ill patients is currently unclear and data for both the risk and ...
Hans-Jörg Gillmann, Jessica Reichart, Andreas Leffler, Thomas Stueber   +3 more
doaj   +3 more sources

Efficacy and safety of a fixed-dose oral tramadol–dipyrone combination for postoperative analgesia in dogs undergoing ovariohysterectomy and unilateral mastectomy: a randomized clinical trial [PDF]

Frontiers in Veterinary Science
IntroductionTo evaluate the analgesic efficacy and safety of an oral tramadol–dipyrone combination (Sindolor®) compared with tramadol or dipyrone alone in dogs undergoing ovariohysterectomy and unilateral mastectomy.MethodsThirty client-owned female dogs
Sandra Mastrocinque, Sandra Mastrocinque, Karina Velloso Braga Yazbek, Richard Barrientos Rossetti, Richard Barrientos Rossetti, Laura Damião Gomes, Jeovan dos Santos Macedo, Amanda Cologneze Brito, Érica Vilela Barreto, Denise Tabacchi Fantoni   +9 more
doaj   +2 more sources

A clinical case and pharmacokinetic analysis of an inadvertent overdose of dipyrone (metamizole) without clinical toxicity: A case report [PDF]

SAGE Open Medical Case Reports
Dipyrone (metamizole) is a widely used non-opioid analgesic. Its use is restricted due to the risk of side effects such as liver toxicity. We report the case of a patient who accidentally received an oral dose of 12.5 g (132 mg/kg) dipyrone.
Andreas Wehrfritz, Stefanie Schmidt, Harald Ihmsen, Steffen Fiedler, Felix Volleth, Roland C. E. Francis, Ixchel Castellanos   +6 more
doaj   +2 more sources

Dipyrone use in Brazil: clinical conditions, sociodemographic characteristics, population attitudes and perceptions [PDF]

Cadernos de Saúde Pública
This study aims to analyze self-reported dipyrone use among the Brazilian population. We used data from the Brazilian National Survey on Access, Use, and Promotion of Rational Use of Medicines (PNAUM), conducted from September 2013 to February 2014 in ...
Eloá Fátima Ferreira de Medeiros, Noêmia Urruth Leão Tavares, Débora Santos Lula Barros, Tatiane da Silva Dal Pizzol, Andréia Turmina Fontanella, Dayde Lane Mendonça-Silva, Sotero Serrate Mengue, Francisco Assis Rocha Neves   +7 more
doaj   +3 more sources

Prevalence and predictors of analgesic use during early pregnancy in a Brazilian population [PDF]

Frontiers in Pharmacology
IntroductionAlthough the use of analgesics is generally not recommended during pregnancy, several studies have reported a high prevalence of use among pregnant women.
Marcella Tapias Passoni, Mariana Regina Rompkovski, Vitória Aline Santana Rios, Daniele Cristine Krebs Ribeiro, Amanda Atuati Maltoni, Carla Giovana Basso, Sara Emilia Lima Tolouei, Juliana Machado Franco, Bianca Manfroi da Silva, Anderson Joel Martino-Andrade, Anderson Joel Martino-Andrade, CARES Study Group, CARES Study Group   +12 more
doaj   +2 more sources

Metamizole-induced agranulocytosis from a German intensive care perspective [PDF]

Frontiers in Medicine
Background/objectivesMetamizole (dipyrone) is a non-opioid analgesic and antipyretic widely used in Germany, with prescriptions having increased more than tenfold since 1997.
Laura Hille, Laura Hille, Martin J. Hug, Tobias Wengenmayer, Hanna Hilger, Paul Marc Biever   +5 more
doaj   +2 more sources

Association of analgesic pharmacological effect with pain site in pediatric oncology patients [PDF]

Frontiers in Pain Research
BackgroundCancer in children and adolescents is frequently associated with pain, which is one of the most common and distressing symptoms reported by patients. Effective pain management remains a major concern for healthcare teams.
Flavia Carvalho Marotta, Eduardo Ladeia Leal, Isabelle Alvarenga Oliveira, Thuane Sales Gonçalves, Silmara Rodrigues Machado, Carolina Paula Jesus Kasa, Paulo Caleb Júnior Lima Santos   +6 more
doaj   +2 more sources

Cannabinoid Effects of Metamizol/Dipyrone: A Possible Second Life in Pediatric Anesthesia for a Vintage Drug [PDF]

Biomedicines
Background: Metamizol (dipyrone) is a widely used analgesic and antipyretic drug in several European countries, particularly for postoperative pain management in both adult and pediatric populations.
Alessandro Vittori, Cecilia Di Fabio, Andrea Scardaci, Francesco Smedile, Ilaria Mascilini, Elisa Francia, Corrado Cecchetti, Franco Marinangeli, Giuliano Marchetti, Teresa Grimaldi Capitello, Marco Cascella   +10 more
doaj   +2 more sources

Cross-Reactivity: a Case of Paracetamol-Induced Generalized Bullous Fixed Drug Eruption Followed by Dipyrone-Induced Fixed Drug Eruption [PDF]

Clinical, Cosmetic and Investigational Dermatology
Yuanyuan Wang,1,* Huan Xue,2,* Hejun Dai,1 Lianjuan Yang1 1Department of Medical Mycology, Center of Infectious Skin Diseases, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of China; 2Department
Wang Y, Xue H, Dai H, Yang L
doaj   +2 more sources