A clinical case and pharmacokinetic analysis of an inadvertent overdose of dipyrone (metamizole) without clinical toxicity: A case report [PDF]
SAGE Open Medical Case ReportsDipyrone (metamizole) is a widely used non-opioid analgesic. Its use is restricted due to the risk of side effects such as liver toxicity. We report the case of a patient who accidentally received an oral dose of 12.5 g (132 mg/kg) dipyrone.
Andreas Wehrfritz +6 more
doaj +2 more sources
Antipyretic effect of oral dipyrone (Metamizole) compared to oral ibuprofen in febrile children: a systematic review and meta-analysis [PDF]
BMC PediatricsBackground Dipyrone (Metamizole) is a potent pain reliever and fever reducer with muscle relaxant properties, most commonly used as an analgesic and antipyretic agent.
Maged Alnajar +5 more
doaj +2 more sources
Prevalence and predictors of analgesic use during early pregnancy in a Brazilian population [PDF]
Frontiers in PharmacologyIntroductionAlthough the use of analgesics is generally not recommended during pregnancy, several studies have reported a high prevalence of use among pregnant women.
Marcella Tapias Passoni +12 more
doaj +2 more sources
Metamizole-induced agranulocytosis from a German intensive care perspective [PDF]
Frontiers in MedicineBackground/objectivesMetamizole (dipyrone) is a non-opioid analgesic and antipyretic widely used in Germany, with prescriptions having increased more than tenfold since 1997.
Laura Hille +5 more
doaj +2 more sources
Association of analgesic pharmacological effect with pain site in pediatric oncology patients [PDF]
Frontiers in Pain ResearchBackgroundCancer in children and adolescents is frequently associated with pain, which is one of the most common and distressing symptoms reported by patients. Effective pain management remains a major concern for healthcare teams.
Flavia Carvalho Marotta +6 more
doaj +2 more sources
Cannabinoid Effects of Metamizol/Dipyrone: A Possible Second Life in Pediatric Anesthesia for a Vintage Drug [PDF]
BiomedicinesBackground: Metamizol (dipyrone) is a widely used analgesic and antipyretic drug in several European countries, particularly for postoperative pain management in both adult and pediatric populations.
Alessandro Vittori +10 more
doaj +2 more sources
Cross-Reactivity: a Case of Paracetamol-Induced Generalized Bullous Fixed Drug Eruption Followed by Dipyrone-Induced Fixed Drug Eruption [PDF]
Clinical, Cosmetic and Investigational DermatologyYuanyuan Wang,1,* Huan Xue,2,* Hejun Dai,1 Lianjuan Yang1 1Department of Medical Mycology, Center of Infectious Skin Diseases, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of China; 2Department
Wang Y, Xue H, Dai H, Yang L
doaj +2 more sources
The antipyretic effectiveness of dipyrone in the intensive care unit: A retrospective cohort study
PLoS ONE, 2022 Introduction Dipyrone (metamizol) is regularly used in critical care for pain and fever treatment, especially in Germany and Spain. However, indication for antipyretic therapy in critically ill patients is currently unclear and data for both the risk and
Hans-Jörg Gillmann +3 more
doaj +2 more sources
Brazilian Journal of Otorhinolaryngology, 2021 Introduction: Tonsillectomy is the 2nd most common outpatient surgery performed on children in the United States of America. Its main complication is pain, which varies in intensity from moderate to severe.
Maira Isis S. Stangler +3 more
doaj +1 more source
Deficits in pain medication in older adults with chronic pain receiving home care: A cross-sectional study in Germany [PDF]
, 2020 OBJECTIVE: To analyze the pattern and appropriateness of pain medications in older adults receiving home care. METHODS: We performed a prospective cross-sectional study in patients ≥65 years old having chronic pain and receiving home care in Berlin ...
Algharably, Engi +5 more
core +1 more source