Results 31 to 40 of about 6,507 (223)

Pain Management and Analgesics Used in Small Mammals during Post-Operative Period with an Emphasis on Metamizole (Dipyrone) as an Alternative Medication

Molecules, 2022
Metamizole (dipyrone) is a widely used non-opioid analgesic in both human and animal medicine. Metamizole’s safety has been the topic of numerous opposing debates, given the fact that in certain countries metamizole is frequently used as an over-the ...
Georgiana Lupu, L. Bel, S. Andrei
semanticscholar   +1 more source

Real world evidence of the use of metamizole (dipyrone) by the Brazilian population. A retrospective cohort with over 380,000 patients

Einstein, 2022
Objective To determine under which health conditions metamizole (dipyrone) is used as a single drug or as fixed-dose combination. Methods Two retrospective cohorts of Brazilian patients treated with metamizole between January 2015 and December 2017 were ...
Henry Sznejder, Caroline Amand, Andrew Stewart, Ricardo Salazar, Wanessa Alessandra Ruiz Scala   +4 more
semanticscholar   +1 more source

Pharmacokinetics of metamizole (dipyrone) as an add-on in calves undergoing umbilical surgery

PLoS ONE, 2022
This preliminary clinical investigation of the pharmacokinetic behavior of the main metamizole (dipyrone) metabolites 4-methylaminoantipyrine (4-MAA) and 4-aminoantipyrine (4-AA) in calves undergoing umbilical surgery is part of an already published main
D. Fux, M. Metzner, Johanna Brandl, M. Feist, Magdalena Behrendt-Wippermann, A. V. von Thaden, C. Baumgartner   +6 more
semanticscholar   +1 more source

Effects of intratesticular injection of zinc-based solution in rats in combination with anti-inflammatory and analgesic drugs during chemical sterilization [PDF]

Veterinary World, 2018
Aim: Chemical sterilization is a non-surgical method of contraception based on compounds injected into the testis to induce infertility. However, these injections can cause discomfort and pain able to impair the recovery of animals after this treatment ...
Simone Regina Barros de Macedo, Luiz Andre Rodrigues de Lima, Sandra Maria de Torres, Vinicius Vasconcelos Gomes de Oliveira, Rosana Nogueira de Morais, Christina Alves Peixoto, Bruno Mendes Tenorio, Valdemiro Amaro da Silva Junior   +7 more
doaj   +1 more source

Dipyrone has no effects on bone healing of tibial fractures in rats [PDF]

Acta Ortopédica Brasileira, 2014
OBJECTIVE: To evaluate the effect of dipyrone on healing of tibial fractures in rats. METHODS: Fourty-two Wistar rats were used, with mean body weight of 280g.
Julio Cesar Gali, Dennis Sansanovicz, Fernando Carvalho Ventin, Rodrigo Henrique Paes, Francisco Carlos Quevedo, Edie Benedito Caetano   +5 more
doaj   +1 more source

2-Arylpropionic Acid Pyrazolamides as Cannabinoid CB2 Receptor Inverse Agonists Endowed with Anti-Inflammatory Properties

Pharmaceuticals, 2022
Among the most recent proposals regarding the mechanism of action of dipyrone, the modulation of cannabinoid receptors CB1 and CB2 appears to be a promising hypothesis.
Daniela R. de Oliveira, Rodolfo C. Maia, Patrícia R. de Carvalho França, Patrícia D. Fernandes, Gisele Barbosa, Lídia M. Lima, Carlos A. Manssour Fraga   +6 more
doaj   +1 more source

The Ionic Associate of Metamizole as an Electrode-Active Component of a PVC Plasticized Membrane Electrode

Chemosensors, 2022
The technology for manufacturing a film membrane of the metamizole-selective electrode containing ion associate metamizole-octadecylammonium ODAH+MT− as an electrode active component (EAC) has been proposed. The main potentiometric characteristics of the
Sarizhat D. Tataeva, Kurban E. Magomedov, Ruslan Z. Zeynalov, Naida D. Baygishieva, Viktorya S. Magomedova, Alina A. Rabadanova, Farid F. Orudzhev   +6 more
doaj   +1 more source

Single dose dipyrone for acute postoperative pain.

, 2010
BACKGROUND: Dipyrone (metamizole) is a non-steroidal anti-inflammatory drug used in some countries to treat pain (postoperative, colic, cancer, and migraine); it is banned in others because of an association with life-threatening blood agranulocytosis ...
Henry J McQuay, McQuay, HJ, Sheena Derry, Edwards, J, Moore, RA, R Andrew Moore, Jayne Edwards, Meseguer, F, Derry, Sheena, Clara Faura, Derry, S, Faura, C   +11 more
core   +2 more sources

Evidence of the effect of dipyrone on the central nervous system as a determinant of delayed gastric emptying observed in rats after its administration

Brazilian Journal of Medical and Biological Research, 2003
Dipyrone administered intravenously (iv) delays gastric emptying (GE) in rats. The objectives of the present study were to assess: 1) the effect of the dose of dipyrone and time after its iv administration on GE in rats, 2) the effect of subdiaphragmatic
E.F. Collares, A.M. Vinagre
doaj   +1 more source

EFFECT OF DIPYRONE ON THE RENAL CLEARANCE AND URINARY EXCRETION OF NORFLOXACIN IN SHEEP [PDF]

Pakistan Veterinary Journal, 2005
The effect of dipyrone on the renal clearance and urinary excretion of norfloxacin was investigated in eight healthy female sheep. In each animal, after a single intramuscular administration of norfloxacin, 5 mg/kg body weight, a wash out period of seven
I. Javed, M. Shahzad, T. Khaliq, F. H. Khan, F. Muhammad, B. Aslam and Z. Iqbal
doaj