Results 31 to 40 of about 6,728 (201)

EFFECT OF DIPYRONE ON THE RENAL CLEARANCE AND URINARY EXCRETION OF NORFLOXACIN IN SHEEP [PDF]

open access: yesPakistan Veterinary Journal, 2005
The effect of dipyrone on the renal clearance and urinary excretion of norfloxacin was investigated in eight healthy female sheep. In each animal, after a single intramuscular administration of norfloxacin, 5 mg/kg body weight, a wash out period of seven
I. Javed, M. Shahzad, T. Khaliq, F. H. Khan, F. Muhammad, B. Aslam and Z. Iqbal
doaj  

Active metabolites of dipyrone induce a redox-dependent activation of the ion channels TRPA1 and TRPV1

open access: yesPAIN Reports, 2019
. Introduction:. The nonopioid analgesic and antipyretic dipyrone (metamizol) is frequently used worldwide. Dipyrone is a prodrug, and the metabolites 4-N-methylaminoantipyrine (MAA) and 4-aminoantipyrine (AA) seem to induce analgesia and antipyresia in ...
Stefan Alexander Schenk   +4 more
doaj   +1 more source

The long and winding road of non steroidal antinflammatory drugs and paracetamol in cancer pain management: A critical review [PDF]

open access: yes, 2013
The aim of this review was to assess the value of NSAIDs and paracetamol in patients with cancer pain to update a previous review performed ten years ago on this topic.
GIARRATANO, Antonino, Mercadante, S
core   +1 more source

Do endogenous opioids and nitric oxide participate in the anticonvulsant action of dipyrone?

open access: yesBrazilian Journal of Medical and Biological Research, 2003
It was previously reported that systemic administration of dipyrone inhibited the tonic component of generalized tonic-clonic seizures in both the electroshock and the audiogenic seizure models.
G.M.L. Reis   +3 more
doaj   +1 more source

Lack of influence of the COX inhibitors metamizol and diclofenac on platelet GPIIb/IIIa and P-selectin expression [PDF]

open access: yes, 2004
Background The effect of non-steroidal anti-inflammatory drugs (NSAIDs) for reduced platelet aggregation and thromboxane A2 synthesis has been well documented. However, the influence on platelet function is not fully explained.
Dirk Scheinichen   +34 more
core   +1 more source

Investigation of pharmaceutical metabolites in environmental waters by LC-MS/MS [PDF]

open access: yes, 2014
Pharmaceuticals, once ingested, are commonly metabolized in the body into more polar and soluble forms. These compounds might not be completely removed in the wastewater treatment plants and consequently being discharged into the aquatic ecosystem.
GRACIA LOR, EMMA   +4 more
core   +1 more source

Atividade antinociceptiva de Ipomoea imperati (Vahl) Griseb., Convolvulaceae [PDF]

open access: yes, 2010
Ipomoea imperati (Vahl) Griseb., Convolvulaceae, is used in folk medicine for the treatment of inflammation, swelling and wounds, as well as to treat pains after childbirth and for stomach problems.
AUR, Carlos R.   +6 more
core   +1 more source

Antipyretic efficacy and tolerability of oral ibuprofen, oral dipyrone and intramuscular dipyrone in children: a randomized controlled trial

open access: yesSão Paulo Medical Journal
CONTEXT AND OBJECTIVE: Dipyrone is a widely used over-the-counter antipyretic in Latin America, and elsewhere among Latin immigrants. Despite limited evidence, physicians often prescribe oral ibuprofen or intramuscular dipyrone as the most effective ...
Judith Prado   +4 more
doaj   +1 more source

Dipyrone use in Brazil: clinical conditions, sociodemographic characteristics, population attitudes and perceptions [PDF]

open access: yesCadernos de Saúde Pública
This study aims to analyze self-reported dipyrone use among the Brazilian population. We used data from the Brazilian National Survey on Access, Use, and Promotion of Rational Use of Medicines (PNAUM), conducted from September 2013 to February 2014 in ...
Eloá Fátima Ferreira de Medeiros   +7 more
doaj   +2 more sources

Fast determination of 40 drugs in water using large volume direct injection liquid chromatography–tandem mass spectrometry [PDF]

open access: yes, 2015
This work describes a rapid analytical method based on direct sample injection of water samples for the simultaneous identification/quantification of 40 emerging compounds, including pharmaceuticals and drugs of abuse.
Aranda Mares, José Luis   +6 more
core   +1 more source

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