Results 1 to 10 of about 5,434 (205)
Metamizole-associated adverse events: a systematic review and meta-analysis. [PDF]
PLoS ONE, 2015 BackgroundMetamizole is used to treat pain in many parts of the world. Information on the safety profile of metamizole is scarce; no conclusive summary of the literature exists.ObjectiveTo determine whether metamizole is clinically safe compared to ...
Thomas Kötter +7 more
doaj +3 more sources
Comparative Effects of Metamizole (Dipyrone) and Naproxen on Renal Function and Prostacyclin Synthesis in Salt-Depleted Healthy Subjects - A Randomized Controlled Parallel Group Study [PDF]
Frontiers in Pharmacology, 2021 Aim: The objective was to investigate the effect of metamizole on renal function in healthy, salt-depleted volunteers. In addition, the pharmacokinetics of the four major metamizole metabolites were assessed and correlated with the pharmacodynamic effect
Lea S Blaser +14 more
doaj +2 more sources
Metamizole Utilization and Expenditure During 6-Year Period: Serbia vs. Croatia [PDF]
Frontiers in Public Health, 2018 Background: Metamizole is a medication with analgesic, antipyretic, spasmolytic, and weak anti-inflammatory effects. The aim of our study was to evaluate a six-year trend in the utilization and expenditure of metamizole in comparison to other group of ...
Milijana Miljkovic +6 more
doaj +2 more sources
Jurnal Natural, 2021 Metamizole is a nonsteroidal antiinflammatory drug (NSAID) that functions as an analgesic, antipyretic, and antiinflammatory. Examination of active substance contents is a requirement that must be met to ensure the quality of drug preparations.
NERDY NERDY +4 more
doaj +3 more sources
Acute Liver Failure in a Patient Treated With Metamizole
Frontiers in Pharmacology, 2019 We report on a patient who developed acute liver failure while being treated with metamizole. After liver transplantation, the patient recovered rapidly. Liver biopsy showed massive necrosis and lobular infiltration of lymphocytes.
Philipp Krisai +2 more
exaly +3 more sources
Proliferative effects of metamizole sodium on U-87 MG glioblastoma cell line: a pain killer or a killer? [PDF]
World Cancer Research Journal, 2021 OBJECTIVE: During cancer treatment, painkillers are often used to alleviate patient pain. Metamizole is a pyrazolone derivative and a non-opioid pain reliever.
O. Koçak, E. Şimşek
doaj +1 more source
Juxta: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga, 2021 Introduction: Traumatic brain injury (TBI) has a concerning incidence rate. One of the therapies for patients with TBI is non-steroidal anti-inflammatory drugs (NSAID) administration as an analgesic with proper adherence to achieve optimal therapy ...
Finna Permata Putri +3 more
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Case Report: Simultaneously Induced Neutropenia and Hemolysis After a Single Metamizole Dose
Drugs in R&D, 2023 Background and objective Metamizole is a non-opioid ampyrone sulfonate compound with potent analgesic, antipyretic, and spasmolytic effects. Agranulocytosis is a rare life-threatening complication of metamizole.
Raphael Allgaier +5 more
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Case series: Heinz body formation in 13 multimorbid dogs following metamizole administration
Frontiers in Veterinary Science, 2023 BackgroundHeinz Body (HB) anemia is a result of oxidative damage and is an uncommon condition in dogs relative to cats. In this retrospective case series, clinical features, laboratory values, concurrent diseases, and outcomes of 13 multimorbid dogs that
Vera Geisen +2 more
doaj +1 more source
pharma-kritik, 2009 Metamizol, ein seit fast 90 Jahren verfügbares Pyrazolon-Schmerzmittel, ist in seinen positiven und negativen Eigenschaften weit weniger gut dokumentiert als moderne Medikamente. In Anbetracht des ungenügend definierten Nutzen/Risiko-Verhältnisses sollte es so zurückhaltend wie möglich verschrieben werden. Als «Allround»-Schmerzmittel ist es zweifellos
openaire +1 more source