Results 1 to 10 of about 563,341 (187)

Histopathological effects of intramuscular metamizole sodium on rat sciatic nerve [PDF]

Iranian Journal of Basic Medical Sciences, 2016
Objective(s): We investigated the histopathological effects of metamizole sodium (MS) on the sciatic nerve.  Materials and Methods: This study was performed using 48 adult male Wistar albino rats. Ten groups were constituted with 6 rats in each group. MS
Abdurrahman Emir, Yıldıray Kalkan, Habib Bostan   +2 more
doaj   +8 more sources

Influence of Metamizole on Antitumour Activity of Risedronate Sodium in In Vitro Studies on Canine (D-17) and Human (U-2 OS) Osteosarcoma Cell Lines [PDF]

Biomedicines
The availability of metamizole varies greatly around the world. There are countries such as the USA, UK, or Australia where the use of metamizole is completely forbidden, and there are also countries where this drug is available only on prescription (e.g.
Dominik Poradowski, Aleksander Chrószcz, Radosław Spychaj, Joanna Wolińska, Vedat Onar   +4 more
doaj   +5 more sources

Evaluating the analgesic effect of metamizole in the mouse model for DSS-induced acute colitis [PDF]

Frontiers in Physiology
A commonly used mouse model of ulcerative colitis is the Dextran Sodium Sulphate (DSS) colitis model, including symptoms of weight loss, softening of stool up to diarrhea, and abdominal pain.
D. T. Jacob, L. M. Keubler, A. Glasenapp, K. Selke, M. Buettner, L. Wenzel, S. Buchheister, S. Lutscher, H. Bähre, M. Bankstahl, M. Bankstahl, A. Bleich, C. Häger   +12 more
doaj   +3 more sources

Metamizole-induced agranulocytosis from a German intensive care perspective [PDF]

Frontiers in Medicine
Background/objectivesMetamizole (dipyrone) is a non-opioid analgesic and antipyretic widely used in Germany, with prescriptions having increased more than tenfold since 1997.
Laura Hille, Laura Hille, Martin J. Hug, Tobias Wengenmayer, Hanna Hilger, Paul Marc Biever   +5 more
doaj   +3 more sources

Comparative Effects of Metamizole (Dipyrone) and Naproxen on Renal Function and Prostacyclin Synthesis in Salt-Depleted Healthy Subjects - A Randomized Controlled Parallel Group Study [PDF]

Frontiers in Pharmacology, 2021
Aim: The objective was to investigate the effect of metamizole on renal function in healthy, salt-depleted volunteers. In addition, the pharmacokinetics of the four major metamizole metabolites were assessed and correlated with the pharmacodynamic effect
Lea S Blaser, Urs Duthaler, Urs Duthaler, Jamal Bouitbir, Jamal Bouitbir, Anne B Leuppi-Taegtmeyer, Anne B Leuppi-Taegtmeyer, Evangelia Liakoni, Reto Dolf, Michael Mayr, Jürgen Drewe, Stephan Krähenbühl, Stephan Krähenbühl, Stephan Krähenbühl, Manuel Haschke   +14 more
doaj   +4 more sources

Proliferative effects of metamizole sodium on U-87 MG glioblastoma cell line: a pain killer or a killer? [PDF]

World Cancer Research Journal, 2021
OBJECTIVE: During cancer treatment, painkillers are often used to alleviate patient pain. Metamizole is a pyrazolone derivative and a non-opioid pain reliever.
O. Koçak, E. Şimşek
doaj   +2 more sources

A Prospective Case Series on the Effect of Cross-Linked Hyaluronic Acid Combined With a Collagen Sponge in the Treatment of Alveolar Osteitis. [PDF]

Clin Exp Dent Res
ABSTRACT Objectives This case series reports on alveolar osteitis (AO) treatment outcomes after standard AO therapy combined with cross‐linked hyaluronic acid (xHyA) and a collagen sponge. Material and Methods Nine patients fulfilling the AO criteria after permanent tooth extraction were included.
Domic D, Bauer P, Ottenbacher N, Bertl K, Ulm C, Stavropoulos A.   +5 more
europepmc   +2 more sources

Clinical-Pharmacological Drug Information Center of Hannover Medical School: Update From a Tertiary Care University Hospital (2022-2024). [PDF]

Pharmacol Res Perspect
ABSTRACT Drug information centers (DICs) are institutions dedicated to providing independent and up‐to‐date information on medications and their usage to healthcare professionals. Here, we provide an update from the clinical‐pharmacological DIC of Hannover Medical School, covering the period from April 2022 to December 2024.
Heck J, Stichtenoth DO, Schröder C, Sabau R, Heim AK, Koop F, Pape T, Schröder S, Westhoff MS, Krichevsky B, Klietz M, Greten S, Schumacher C.   +12 more
europepmc   +2 more sources

Comparison of the Effect of Lidocaine in Combination to Meloxicam and/or Metamizole Sodium Epidurally on Analgesic Parameters, and Health Status of Holstein Cattle [PDF]

Iranian Journal of Veterinary Surgery, 2020
Objective- This practice performed to compare the quality of analgesia, hematological parameters, and prevalence of cardiac dysrhythmias following epidural administration of lidocaine, lidocaine-meloxicam, and lidocaine-Metamizole sodium in cows. Animals-
Khosro Safari-Nikoo, Abbas Raisi, Amir Zakian, Ahmad Reza Mohamadnia   +3 more
doaj   +1 more source

THE STUDY OF SOME PROMISING PHARMACEUTICAL COMPOSITIONS WITH UREASE INHIBITORY ACTIVITY FOR THE TUBERCULOSIS REACTIVATION PREVENTION [PDF]

Annals of Mechnikov's Institute, 2017
Introduction. The aim of the study was to study the ability to inhibit urease by some pharmaceutical compositions that are promising in the prevention of tuberculosis reactivation .
Bomko T.V., Martynov A.V., Nosalskaya T.N.   +2 more
doaj   +1 more source