Results 1 to 10 of about 71,998 (296)
Journal of Medicinal Chemistry, 2020 The synthesis, characterization, biological activity,and toxicology of sila-ibuprofen, a silicon derivative of the most common nonsteroidal anti-inflammatory drug, is reported.
Justies, Aileen +16 more
core +4 more sources
Accumulation of ibuprofen in endemic amphipods of Lake Baikal [PDF]
PeerJPharmaceutical pollutants, including ibuprofen, are now ubiquitously detected in global aquatic ecosystems, exerting significant negative ecological impacts.
Tamara Yu Telnova +12 more
doaj +3 more sources
Molecules, 2012 A novel application of whole cells of Nocardia corallina B-276 for the deracemisation of ibuprofen is reported. This microorganism successfully hydrolysed ibuprofen nitrile to ibuprofen amide, and ibuprofen amide to ibuprofen, using a suspension of cells
Myrna Solís-Oba +4 more
doaj +2 more sources
Comparative pharmacology of s(+)- ibuprofen and (RS)- ibuprofen
Clinical Rheumatology, 2001 Racemic ibuprofen, which contains equal quantities of R(-)-ibuprofen and S(+)-ibuprofen, has been used as an anti-inflammatory and analgesic agent for over 30 years. Although the S(+)-enantiomer is capable of inhibiting cyclooxygenase (COX) at clinically
Evans, A.M.
core +3 more sources
In-vitro diffusion study of ibuprofen--cyclodextrin inclusion complex nanogel [PDF]
Pharmaciana, 2021 The inclusion complex is one way to enhance active substance solubility, affecting medicine dissolution and penetration. The inclusion complex is formed by utilizing b-cyclodextrin as the host of the active compounds.
Fitrianti Darusman +4 more
doaj +1 more source
Differential renal adverse effects of ibuprofen and indomethacin in preterm infants: a review
Clinical Pharmacology: Advances and Applications, 2014 Gian Maria Pacifici Medical School, Department of Translational Research and New Technologies in Medicine and Surgery, Section of Pharmacology, University of Pisa, Pisa, Italy Objective: The objective of this study was to evaluate the extent of renal ...
Pacifici GM
doaj +1 more source
Effect of the type of amino acid on the biodegradation of ibuprofen derivatives [PDF]
Archives of Environmental Protection, 2023 Water pollution caused by anthropogenic activity is a huge environmental problem. Huge amounts of consumed medicinal substances cause them to get into the environment.
Paula Elżbieta Ossowicz-Rupniewska +5 more
doaj +1 more source
Ibuprofen Degradation and Associated Bacterial Communities in Hyporheic Zone Sediments
Microorganisms, 2020 Ibuprofen, a non-steroidal anti-inflammatory pain reliever, is among pharmaceutical residues of environmental concern ubiquitously detected in wastewater effluents and receiving rivers.
Cyrus Rutere +4 more
doaj +1 more source
Ibuprofen and sila-ibuprofen: polarization effects in the crystal and enzyme environments [PDF]
, 2021 Sila-ibuprofen is a new potential nonsteroidal anti-inflammatory drug which deviates from its parent ibuprofen in terms of the electrostatic potential around the carbon/silicon-switched C/Si—H group.
Kleemiss, Florian +6 more
core +1 more source
Safety of ibuprofen in infants younger than six months: A retrospective cohort study. [PDF]
PLoS ONE, 2018 OBJECTIVE:We hypothesized (1) that gastrointestinal (GI) and renal adverse events (AE) would occur more often in infants first prescribed ibuprofen before rather than after six months of age and (2) that ibuprofen would be associated with more adverse ...
Paul Walsh +2 more
doaj +1 more source