Results 31 to 40 of about 71,998 (296)
Italian Journal of Pediatrics, 2021 Purpose of review Despite its recognized efficacy and tolerability profile, during the last decade a rise of adverse events following ibuprofen administration in children has been reported, including a possible role in worsening the clinical course of ...
Lucia Quaglietta +2 more
doaj +1 more source
Response of Rhodococcus cerastii IEGM 1278 to toxic effects of ibuprofen.
PLoS ONE, 2021 The article expands our knowledge on the variety of biodegraders of ibuprofen, one of the most frequently detected non-steroidal anti-inflammatory drugs in the environment.
Irina B Ivshina +3 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective Although the definition of a gout flare is well established, the state of gout flare resolution has not yet been defined. This study aimed to explore patients’ experiences and perceptions of gout flare resolution. Methods Semistructured interviews were conducted with 24 people with gout, guided by open‐ended questions exploring their ...
Sarah Stewart +5 more
wiley +1 more source
DNA‐mimic for Specific Surface Functionalization of Zr‐MOFs for Bacterial Targeting
Angewandte Chemie, EarlyView.We introduce phosphotyrosine‐modified PNA as a superior, single‐step post‐synthesis surface coating for PCN‐222. The DNA mimic allows for controlled post‐functionalization with single‐stranded DNA for the attachment of protein moieties for bacterial targeting. ABSTRACT Nanosized metal–organic frameworks (MOFs) are versatile platforms used in biomedical
Anna Scheeder +9 more
wiley +2 more sources
Revista de Ciências Farmacêuticas Básica e Aplicada, 2013 Ibuprofen is widely commercialized in racemic form. Although metabolic chiral inversion occurs through the conversion of R(-)-ibuprofen to S(+)-ibuprofen and the latter enantiomer is considered the active form, clinical trials involving the ...
Flavio Henrique Nuevo Benez +7 more
doaj +2 more sources
Decreased plasma levels of PDGF-BB, VEGF-A, and HIF-2α in preterm infants after ibuprofen treatment
Frontiers in Pediatrics, 2022 IntroductionIbuprofen is one of the most common non-steroidal anti-inflammatory drugs used to close patent ductus arteriosus (PDA) in preterm infants. PDA is associated with bronchopulmonary dysplasia (BPD), while PDA closure by ibuprofen did not reduce ...
Xuemei Huang +12 more
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Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis
Angewandte Chemie, EarlyView.Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley +2 more sources
Ibuprofen as an Emerging Contaminant of Concern: Occurrence in Southeast Asia Water Environment [PDF]
E3S Web of ConferencesIbuprofen is the third most salable pharmaceutical worldwide even being sold in the absence of prescription. This drug is not thoroughly metabolized and excreted into wastewater as an unchanged molecule and its metabolites.
Trianda Yenni +2 more
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EFFECT OF CELLULOSIC POLYMERS ON THE PHYSICAL PROPERTIES AND DISSOLUTION OF IBUPROFEN GRANULES [PDF]
Bulletin of Pharmaceutical Sciences. Assiut University, 1992 Ibuprofen sustained release granules were prepared using ce11ulosic polymers including, ethy1cel1u1ose 20, hydroxypropyl methyl cellulose (Pharmacoat 606) and hydroxypropyl methy1 cellulose phthalate (HP 55 F).
E. Samy +4 more
doaj +1 more source
Application of Ibuprofen Sodium Dihydrate for Thermochemical Energy Storage
Advanced Functional Materials, EarlyView.Ibuprofen sodium dihydrate is introduced as a durable organic salt hydrate for low‐temperature thermochemical energy storage, operating within 60°C–110°C with high energy density. At the material level, it delivers ∼99.9% cycling efficiency over 150 cycles without deliquescence, enabled by a dual energy‐storage mechanism coupling dehydration and phase ...
Kavin Chakravarthy Thangaraj +10 more
wiley +1 more source