Results 11 to 20 of about 55,128 (251)

Continuous Melt Granulation for Taste-Masking of Ibuprofen

open access: yesPharmaceutics, 2021
Taste-masking of drugs, particularly to produce formulations for pediatric patients, can be challenging and require complex manufacturing approaches. The objective of this study was to produce taste-masked ibuprofen granules using a novel process, twin ...
Seth P. Forster, David B. Lebo
doaj   +1 more source

EFEK ULCEROGENIC DISPERSI PADAT IBUPROFEN-POLIVINILPIROLIDON (PVP) PADA TIKUS PUTIH JANTAN

open access: yesPharmaciana, 2013
Ibuprofen is an anti inflammatory, analgesic, and antipyretic agent. It has low solubility and bioavailability. The administration of ibuprofen in a long time and high dose can increased of side effect at gastrointestinal (peptic ulcer). This study was
Ririt Vita Febrianti , Iis Wahyuningsih
doaj   +1 more source

An observational cohort study comparing ibuprofen and oxycodone in children with fractures.

open access: yesPLoS ONE, 2021
ObjectiveTo compare the effectiveness and safety of prescribing ibuprofen and oxycodone for at-home management of children's fracture pain.MethodsA prospective observational cohort was conducted at the Stollery Children's Hospital pediatric emergency ...
Samina Ali   +8 more
doaj   +1 more source

Synthesis of Spin-Labeled Ibuprofen and Its Interaction with Lipid Membranes

open access: yesMolecules, 2022
Ibuprofen is a non-steroidal anti-inflammatory drug possessing analgesic and antipyretic activity. Electron paramagnetic resonance (EPR) spectroscopy could be applied to study its interaction with biological membranes and proteins if its spin-labeled ...
Denis S. Baranov   +2 more
doaj   +1 more source

Response of Rhodococcus cerastii IEGM 1278 to toxic effects of ibuprofen.

open access: yesPLoS ONE, 2021
The article expands our knowledge on the variety of biodegraders of ibuprofen, one of the most frequently detected non-steroidal anti-inflammatory drugs in the environment.
Irina B Ivshina   +3 more
doaj   +2 more sources

Uji Drug Loading Ibuprofen Pada Material UiO-66 (Zr-Metal Organic Framework)

open access: yesJurnal Kimia Riset, 2019
Tujuan dari penelitian ini adalah untuk mengetahui nilai loading ibuprofen pada material UiO-66 (Zr-Metal Organic Framework). Pada penelitian ini, dilakukan variasi lama perendaman 12, 24, 36, 48, 60 dan 72 jam, sehingga didapatkan nilai drug loading ...
Tri Ana Mulyati, Fery Eko Pujiono
doaj   +1 more source

The Intestinal and Biliary Metabolites of Ibuprofen in the Rat with Experimental Hyperglycemia

open access: yesMolecules, 2022
Hyperglycemia is reported to be associated with oxidative stress. It can result in changes in the activities of drug-metabolizing enzymes and membrane-integrated transporters, which can modify the fate of drugs and other xenobiotics; furthermore, it can ...
Hawsar Othman Mohammed   +3 more
doaj   +1 more source

Comparison of diclofenac gel, ibuprofen gel, and ibuprofen gel with levomenthol for the topical treatment of pain associated with musculoskeletal injuries

open access: yesJournal of International Medical Research, 2019
Objective To determine whether 3% w/w levomenthol added to ibuprofen gel (5% w/w) improves its efficacy compared with ibuprofen gel alone or diclofenac gel (1.16%) for the treatment of soft-tissue injuries. Methods A total of 182 patients with acute soft-
Alan G. Wade   +4 more
doaj   +1 more source

Hydrolysis of Ibuprofen Nitrile and Ibuprofen Amide and Deracemisation of Ibuprofen Using Nocardia corallina B-276

open access: yesMolecules, 2012
A novel application of whole cells of Nocardia corallina B-276 for the deracemisation of ibuprofen is reported. This microorganism successfully hydrolysed ibuprofen nitrile to ibuprofen amide, and ibuprofen amide to ibuprofen, using a suspension of cells
Myrna Solís-Oba   +4 more
doaj   +1 more source

Enzymatic Hydrolytic Resolution of Racemic Ibuprofen Ethyl Ester Using an Ionic Liquid as Cosolvent

open access: yesMolecules, 2016
The aim of this study was to develop an ionic liquid (IL) system for the enzymatic resolution of racemic ibuprofen ethyl ester to produce (S)-ibuprofen. Nineteen ILs were selected for use in buffer systems to investigate the effects of ILs as cosolvents ...
Tao Wei   +5 more
doaj   +1 more source

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