Continuous Melt Granulation for Taste-Masking of Ibuprofen
Pharmaceutics, 2021 Taste-masking of drugs, particularly to produce formulations for pediatric patients, can be challenging and require complex manufacturing approaches. The objective of this study was to produce taste-masked ibuprofen granules using a novel process, twin ...
Seth P. Forster, David B. Lebo
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Ibuprofen-loaded calcium phosphate granules : combination of innovative characterization methods to relate mechanical strength to drug location [PDF]
, 2010 This paper studies the impact of the location of a drug substance on the physicochemical and mechanical properties of two types of calcium phosphate granules loaded with seven different contents of ibuprofen, ranging from 1.75% to 46%.
Ahola +44 more
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Journal of Tropical Pharmacy and Chemistry, 2016 Ibuprofen is one of the NSAID (NonSteroid Anti Inflamation Drug) drugs that has been widely used as antipyretic agent, analgesic dan anti-inflamation. Vitamin C is an important nutrient for the body and has been widely used to maintain health.
Sattrio Desrianto Prabowo +2 more
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In Silico screening of nonsteroidal anti-inflammatory drugs and their combined action on Prostaglandin H Synthase-1 [PDF]
, 2010 The detailed kinetic model of Prostaglandin H Synthase-1 (PGHS-1) was applied to in silico screening of dose-dependencies for the different types of nonsteroidal anti-inflammatory drugs (NSAIDs), such as: reversible/irreversible, nonselective/selective ...
Demin, Oleg +5 more
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EFEK ULCEROGENIC DISPERSI PADAT IBUPROFEN-POLIVINILPIROLIDON (PVP) PADA TIKUS PUTIH JANTAN
Pharmaciana, 2013 Ibuprofen is an anti inflammatory, analgesic, and antipyretic agent. It has low solubility and bioavailability. The administration of ibuprofen in a long time and high dose can increased of side effect at gastrointestinal (peptic ulcer). This study was
Ririt Vita Febrianti , Iis Wahyuningsih
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An observational cohort study comparing ibuprofen and oxycodone in children with fractures.
PLoS ONE, 2021 ObjectiveTo compare the effectiveness and safety of prescribing ibuprofen and oxycodone for at-home management of children's fracture pain.MethodsA prospective observational cohort was conducted at the Stollery Children's Hospital pediatric emergency ...
Samina Ali +8 more
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Topical agents or dressings for pain in venous leg ulcers. [PDF]
, 2010 Venous leg ulcers affect up to 1% of people at some time in their lives and are often painful. The main treatments are compression bandages and dressings.
Briggs, M +2 more
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The dissolution and solid-state behaviours of coground ibuprofen–glucosamine HCl [PDF]
, 2014 The cogrinding technique is one of most effective methods for improving the dissolution of poorly water-soluble drugs and it is superior to other approaches from an economical as well as an environmental standpoint, as the technique does not require any ...
Ali Nokhodchi +8 more
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The Intestinal and Biliary Metabolites of Ibuprofen in the Rat with Experimental Hyperglycemia
Molecules, 2022 Hyperglycemia is reported to be associated with oxidative stress. It can result in changes in the activities of drug-metabolizing enzymes and membrane-integrated transporters, which can modify the fate of drugs and other xenobiotics; furthermore, it can ...
Hawsar Othman Mohammed +3 more
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Response of Rhodococcus cerastii IEGM 1278 to toxic effects of ibuprofen.
PLoS ONE, 2021 The article expands our knowledge on the variety of biodegraders of ibuprofen, one of the most frequently detected non-steroidal anti-inflammatory drugs in the environment.
Irina B Ivshina +3 more
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