Results 11 to 20 of about 71,998 (296)

Supplementary material from: Genetic characterization of the ibuprofen degradative pathway of Rhizorhabdus wittichii MPO218 [PDF]

open access: yes, 2022
Supplementary materialIbuprofen is one of the most common drugs found as contaminants in soils, sediments and waters. Although several microorganisms able to metabolize ibuprofen have been described, the metabolic pathways and factors limiting ...
Aulestia, Magaly   +4 more
core   +1 more source

A Randomized, Double-Blind, Placebo-Controlled Trial of Ibuprofen Lysinate in Comparison to Ibuprofen Acid for Acute Postoperative Dental Pain

open access: yesPain and Therapy, 2020
Introduction Ibuprofen acid is poorly soluble in the stomach, thus reaching maximum plasma levels at approximately 90 min post-dose. Ibuprofen lysinate has been developed to accelerate absorption of ibuprofen to shorten the time to analgesic efficacy ...
Ján Kyselovič   +3 more
doaj   +1 more source

Ibuprofen alters epoxide hydrolase activity and epoxy-oxylipin metabolites associated with different metabolic pathways in murine livers

open access: yesScientific Reports, 2021
Over the last decade oxylipins have become more recognized for their involvement in several diseases. Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen are known to inhibit cyclooxygenase (COX) enzymes, but how NSAIDs affect oxylipins, in ...
Shuchita Tiwari   +5 more
doaj   +1 more source

Clinical safety of ibuprofen in pediatric practice

open access: yesZdorovʹe Rebenka, 2021
The article presents a review of the literature on the side effects of ibuprofen in children. The international guidelines recommend ibuprofen as an antipyretic and analgesic drug in pediatrics. The drug is characterized by a high profile of efficacy and
T.P. Borysova
doaj   +1 more source

A comparison of self-reported analgesic use and detection of urinary ibuprofen and acetaminophen metabolites by means of metabonomics (The INTERMAP Study) [PDF]

open access: yes, 2012
Information on dietary supplements, medications, and other xenobiotics in epidemiologic surveys is usually obtained from questionnaires and is subject to recall and reporting biases.
Holmes, Elaine   +15 more
core   +1 more source

Continuous Melt Granulation for Taste-Masking of Ibuprofen

open access: yesPharmaceutics, 2021
Taste-masking of drugs, particularly to produce formulations for pediatric patients, can be challenging and require complex manufacturing approaches. The objective of this study was to produce taste-masked ibuprofen granules using a novel process, twin ...
Seth P. Forster, David B. Lebo
doaj   +1 more source

Perubahan Profil Farmakokinetika Ibuprofen yang Diberikan dengan Kombinasi Vitamin C pada Tikus Putih (Rattus Norvegicus L.)

open access: yesJournal of Tropical Pharmacy and Chemistry, 2016
Ibuprofen is one of the NSAID (NonSteroid Anti Inflamation Drug) drugs that has been widely used as antipyretic agent, analgesic dan anti-inflamation. Vitamin C is an important nutrient for the body and has been widely used to maintain health.
Sattrio Desrianto Prabowo   +2 more
doaj   +1 more source

Ibuprofen-loaded calcium phosphate granules : combination of innovative characterization methods to relate mechanical strength to drug location [PDF]

open access: yes, 2010
This paper studies the impact of the location of a drug substance on the physicochemical and mechanical properties of two types of calcium phosphate granules loaded with seven different contents of ibuprofen, ranging from 1.75% to 46%.
Cazalbou, S.   +9 more
core   +1 more source

Ibuprofen-Loaded ZnO Nanoparticle/Polyacrylonitrile Nanofibers for Dual-Stimulus Sustained Release of Drugs

open access: yes, 2023
Based on the opportunities of ibuprofen administration innovation and challenges associated with the construction of transdermal drug delivery systems using medicated nanoparticles and electrospun nanofiber membranes, we developed a transdermal drug ...
Pingping Zhang (383373)   +8 more
core   +1 more source

EFEK ULCEROGENIC DISPERSI PADAT IBUPROFEN-POLIVINILPIROLIDON (PVP) PADA TIKUS PUTIH JANTAN

open access: yesPharmaciana, 2013
Ibuprofen is an anti inflammatory, analgesic, and antipyretic agent. It has low solubility and bioavailability. The administration of ibuprofen in a long time and high dose can increased of side effect at gastrointestinal (peptic ulcer). This study was
Ririt Vita Febrianti , Iis Wahyuningsih
doaj   +1 more source

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