Results 51 to 60 of about 71,998 (296)

Ibuprofen: Synthesis, production and properties [PDF]

Hemijska Industrija, 2003
Since its introduction in 1969, ibuprofen has become one of the most common painkillers in the world. Ibuprofen in an NSAID (non-steroidal anti-inflammatory drug) and like other drugs of its class it possesses analgetic, antipyretic and anti-inflammatory
Mijin Dušan Ž., Stanković Milena, Petrović Slobodan D.   +2 more
doaj   +1 more source

Prophylactic ibuprofen in premature infants: a multicentre, randomised, double-blind, placebo-controlled trial

, 2004
Background Ibuprofen is used for treatment and prevention of patent ductus arteriosus in low-birthweight infants. Its effects on regional circulations differ from those of indometacin.
Wim Decaluwé, Casaer, A, Joost Weyler, Jespers, Ann, Decaluwe, W, Weyler, Joost J., Debauche, Christian, Harrewijn, I, Karel Allegaert, Weyler, J, Langhendries, JP., Harrewijn, Inge, Inge Harrewijn, Allegaert, K, Ann Jespers, Casaer, Alexandra, Jean-Paul Langhendries, Langhendries, Jean-Paul, Christian Debauche, Van Overmeire, B, Bart Van Overmeire, Decaluw\ue9, Wim, van Overmeire, Bart, Jespers, A, Alexandra Casaer, Allegaert, Karel   +25 more
core   +1 more source

Substrate‐Affinitive P‐Type Azapolycyclic Photosensitizer for Chemoselective Nitrilization Under Mild Conditions

Advanced Science, EarlyView.
We developed a series of quinoxalinoquinoxaline (QQ) photosensitizers featuring high and tunable excited‐state reduction potentials (E(PC•+/PC*) = –1.76 to –2.05 V vs. SCE). Their hydrogen‐bonding interaction with carbonyl substrates enables selective single‐electron transfer events for selective nitrilization of 1° amides, offering a tunable ...
Seongwoo Bae, Dongwook Kim, Jinwoo Kim
wiley   +1 more source

Synthesis, Characteristics, and Pharmaceutical Properties of Ibuprofen-Cyclodextrin-PEG Conjugate

Journal of Chemistry, 2022
The NSAIDs ibuprofen was chemically conjugated to the PEG-graft-β-CyD with an ester bond and its aqueous solubility was clearly improved. The preliminary release profile of ibuprofen in rat gastrointestinal tract contents was performed at 37°C within 12 ...
Qing Huang, Chun Hua Yan, Sheng Xia Luo, Zhi Xin Li, Tai Bao Wei, Zhi Zhong Wang   +5 more
doaj   +1 more source

Autonomous AI‐Driven Design for Skin Product Formulations

Advanced Intelligent Discovery, EarlyView.
This review presents a comprehensive closed‐loop framework for autonomous skin product formulation design. By integrating artificial intelligence‐driven experiment selection with automated multi‐tiered assays, the approach shifts development from trial‐and‐error to intelligent optimisation.
Yu Zhang, Yongrui Xiao, Chunlin Chen, Dimitrios Tsaoulidis, Kai Yang, Tao Chen   +5 more
wiley   +1 more source

The Use of Ibuprofen Arginate in Pain Management Following Third Molar Surgery—A Scoping Review

Applied Sciences
Background: The management of pain and inflammation after third molar extraction is essential for patient comfort and recovery. While conventional ibuprofen is widely used for pain relief, ibuprofen arginate, a formulation aimed at faster absorption, has
Claudia Lorenzi, Ilaria Cammarota, Vincenzo Mazzetti, Claudio Arcuri, Paolo Carosi, Alberto Maria Pujia   +5 more
doaj   +1 more source

Accelerating Discovery of Organic Molecular Crystals via Materials Informatics and Autonomous Experiments

Advanced Intelligent Discovery, EarlyView.
Materials informatics and autonomous experimentation are transforming the discovery of organic molecular crystals. This review presents an integrated molecule–crystal–function–optimization workflow combining machine learning, crystal structure prediction, and Bayesian optimization with robotic platforms.
Takuya Taniguchi, Kazuki Ishizaki, Ryo Fukasawa   +2 more
wiley   +1 more source

Are cytochrome P450 CYP2C8 and CYP2C9 polymorphisms associated with ibuprofen response in very preterm infants?

PLoS ONE, 2010
BackgroundPatent ductus arteriosus (PDA) in extremely preterm infants remains a challenging condition with conflicting treatment strategies. Ibuprofen is currently used to treat PDA with ductal closure failure rate up to 40%.
Xavier Durrmeyer, Shushanik Hovhannisyan, Yves Médard, Evelyne Jacqz-Aigrain, Fabrice Decobert, Jérome Barre, Corinne Alberti, Yannick Aujard, Claude Danan, Olivier Baud   +9 more
doaj   +1 more source

Histidine Supplementation Stabilizes Hearing and Vision and Improves Growth in HARS1‐Related Autosomal Recessive Disorder Associated With Usher‐Like Symptoms

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal recessive HARS1‐related disorder (originally described as Usher syndrome type 3B) caused by a homozygous Y454S variant in the histidyl‐tRNA synthetase gene (HARS1) is characterized by progressive sensorineural hearing and vision loss and respiratory deterioration with risk for sudden death following febrile illnesses.
Victoria Mok Siu, Rosan Kenana, Rana Chakrabarti, Sarah D. P. Wilhelm, Joseph Andrews, Susan J. Leat, Christina Parker, Michael Miller, Leslie A. Nangle, Wendy McCaul, Ashfia Chowdhury, Natalie Hutchings, Ryan A. Adams, Lauren Guy, Mandy Rhody, Verena Juncal, Marisa I. Mendes, Desiree E. C. Smith, Gajja S. Salomons, Angelica A. Moresco, Daphne L. McCulloch, D. Holmes Morton, Ilka U. Heinemann, C. Anthony Rupar   +23 more
wiley   +1 more source

Studi Optimisasi dan Kinetika Adsorpsi Silika dari Lumpur Lapindo dengan Metode Sol-Gel Menggunakan P123-Putih Telur

Alchemy
Dalam penelitian ini, silika yang disintesis dari Lapindo lumpur dengan metode sol-gel menggunakan P123-putih telur dan berhasil diterapkan sebagai adsorben ibuprofen.
Maria Ulfa, Anisa Ayu Solikah, Zahra Ayu Fadhilah, Ida Setiarini, Zulfana Qoulan Syadida   +4 more
doaj   +1 more source