Results 71 to 80 of about 71,998 (296)

Evaluation of drug release kinetics from ibuprofen matrix tablets using HPMC.

, 2006
The aim of this study is to develop a once-daily sustained release matrix tablet of ibuprofen using hydroxypropyl methylcellulose (HPMC) as release controlling factor and to evaluate drug release parameters as per various release kinetic models. In order
Tazeen, Jaweria, Merchant, Hamid A., Shoaib, M Harris, Yousuf, Rabia Ismail   +3 more
core  

Ibuprofen prevents progression of ataxia telangiectasia symptoms in ATM-deficient mice

Journal of Neuroinflammation, 2018
Background Inflammation plays a critical role in accelerating the progression of neurodegenerative diseases, such as Alzheimer’s disease (AD) and ataxia telangiectasia (A-T).
Chin Wai Hui, Xuan Song, Fulin Ma, Xuting Shen, Karl Herrup   +4 more
doaj   +1 more source

Cocrystal of Ibuprofen–Nicotinamide: Solid-State Characterization and In Vivo Analgesic Activity Evaluation

Scientia Pharmaceutica, 2018
Ibuprofen is classified as a BCS class II drug which has low solubility and high permeability. We conducted the formation of the cocrystalline phase of ibuprofen with coformer nicotinamide to increase its solubility.
Yori Yuliandra, Erizal Zaini, Syofyan Syofyan, Wenny Pratiwi, Lidiya Novita Putri, Yuti Sahra Pratiwi, Helmi Arifin   +6 more
doaj   +1 more source

Intravenous ibuprofen: the first injectable product for the treatment of pain and fever

, 2010
P Brandon Bookstaver, April D Miller, Celeste N Rudisill, LeAnn B NorrisDepartment of Clinical Pharmacy and Outcomes Sciences, South Carolina College of Pharmacy, University of South Carolina Campus, Columbia, South Carolina, USAAbstract: This paper ...
Norris, Leann B, April D Miller, Celeste N Rudisill, Rudisill, Celeste N, P Brandon Bookstaver, et al, Bookstaver, P Brandon, Miller, April D   +7 more
core   +1 more source

Prescribing competence: The pros and cons of different methods for assessment

British Journal of Clinical Pharmacology, EarlyView.
Evaluating a medical graduate’s competence in rational prescribing is challenging. With the aim to guide and inspire teachers, this narrative review explores different methods that can be used to assess prescribing competence. Each method has its own advantages and disadvantages, and thus a mix of different assessment methods is needed throughout the ...
David J. Brinkman, Erik M. Donker, Jelle Tichelaar, on behalf of the CP4T programme   +3 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Developing medication independence: The experience of UK teenagers

British Journal of Clinical Pharmacology, EarlyView.
Aims There is a progression through childhood from being provided medications by caregivers to having to take responsibility for medications yourself, but little is known about when the transition of adolescents managing medicines begins. The aim of this study was to obtain a cross‐sectional sample of UK adolescents and when they become independent ...
Holly Hutchins, Charlotte King, Louis Bioletti, Tsegay Gebru, Alder Hey Research Ambassadors, Daniel B. Hawcutt   +5 more
wiley   +1 more source

Transformation of eutectic emulsion to nanosuspension fabricating with solvent evaporation and ultrasonication technique

International Journal of Nanomedicine, 2016
Thawatchai Phaechamud,1 Sarun Tuntarawongsa2 1Department of Pharmaceutical Technology, 2Pharmaceutical Intelligence Unit Prachote Plengwittaya, Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, Thailand Abstract: Eutectic solvent can solubilize
Phaechamud T, Tuntarawongsa S
doaj  

TOIB Study. Are topical or oral ibuprofen equally effective for the treatment of chronic knee pain presenting in primary care: A randomised controlled trial with patient preference study. [ISRCTN79353052] [PDF]

, 2005
Background: Many older people have chronic knee pain. Both topical and oral non- steroidal anti-inflammatory drugs (NSAIDs) are commonly used to treat this.
Spencer, Anne E., Hennessy, Enid M., Cross Pamela L, Spencer, AE, Ashby Deborah, Harding, G, Enid M Hennessy, Anne E Spencer, Harding Geoff, Parsons Suzanne, Underwood, Martin, Letley Louise, Letley, Louise, Martin Underwood, Underwood Martin, TOIB Study Team, Louise Letley, Hennessy Enid M, Underwood, M, Hennessy, EM, Spencer Anne E, Ashby, D, Suzanne Parsons, null null, Cross, Pamela L., Pamela L Cross, Ashby, Deborah, Geoff Harding, Deborah Ashby, Cross, PL, Harding, Geoff, Parsons, Suzanne, Parsons, S, Letley, L   +33 more
core   +1 more source

Systematic review and scoring‐based selection of pharmacokinetic models for precision dosing of vancomycin in neonates and children

British Journal of Clinical Pharmacology, EarlyView.
This systematic review identified 112 population pharmacokinetic models of vancomycin in neonates and children. To support rational model selection for model‐informed precision, we developed and applied expert‐driven, transparent criteria that integrate both methodological rigour and clinical relevance.
Zoë Vander Elst, Pieter‐Jan Spiessens, Dorian Vanneste, Nada Dia, Matthias Gijsen, Isabel Spriet, Karel Allegaert, Erwin Dreesen, Anne Smits   +8 more
wiley   +1 more source