Results 61 to 70 of about 128,729 (286)

The digital code driven autonomous synthesis of ibuprofen automated in a 3D-printer-based robot [PDF]

, 2016
An automated synthesis robot was constructed by modifying an open source 3D printing platform. The resulting automated system was used to 3D print reaction vessels (reactionware) of differing internal volumes using polypropylene feedstock via a fused ...
Cronin, Leroy, Glatzel, Stefan, Kitson, Philip J.   +2 more
core   +2 more sources

Substrate‐Affinitive P‐Type Azapolycyclic Photosensitizer for Chemoselective Nitrilization Under Mild Conditions

Advanced Science, EarlyView.
We developed a series of quinoxalinoquinoxaline (QQ) photosensitizers featuring high and tunable excited‐state reduction potentials (E(PC•+/PC*) = –1.76 to –2.05 V vs. SCE). Their hydrogen‐bonding interaction with carbonyl substrates enables selective single‐electron transfer events for selective nitrilization of 1° amides, offering a tunable ...
Seongwoo Bae, Dongwook Kim, Jinwoo Kim
wiley   +1 more source

Are cytochrome P450 CYP2C8 and CYP2C9 polymorphisms associated with ibuprofen response in very preterm infants?

PLoS ONE, 2010
BackgroundPatent ductus arteriosus (PDA) in extremely preterm infants remains a challenging condition with conflicting treatment strategies. Ibuprofen is currently used to treat PDA with ductal closure failure rate up to 40%.
Xavier Durrmeyer, Shushanik Hovhannisyan, Yves Médard, Evelyne Jacqz-Aigrain, Fabrice Decobert, Jérome Barre, Corinne Alberti, Yannick Aujard, Claude Danan, Olivier Baud   +9 more
doaj   +1 more source

Diagnostic and therapeutic considerations in idiopathic hypereosinophilia with warm autoimmune hemolytic anemia. [PDF]

, 2015
Hypereosinophilic syndrome (HES) encompasses numerous diverse conditions resulting in peripheral hypereosinophilia that cannot be explained by hypersensitivity, infection, or atopy and that is not associated with known systemic diseases with specific ...
Brys, Adam K, Sheth, Milan R, Sohn, David D, Sweidan, Alexander J   +3 more
core   +1 more source

Autonomous AI‐Driven Design for Skin Product Formulations

Advanced Intelligent Discovery, EarlyView.
This review presents a comprehensive closed‐loop framework for autonomous skin product formulation design. By integrating artificial intelligence‐driven experiment selection with automated multi‐tiered assays, the approach shifts development from trial‐and‐error to intelligent optimisation.
Yu Zhang, Yongrui Xiao, Chunlin Chen, Dimitrios Tsaoulidis, Kai Yang, Tao Chen   +5 more
wiley   +1 more source

Studi Optimisasi dan Kinetika Adsorpsi Silika dari Lumpur Lapindo dengan Metode Sol-Gel Menggunakan P123-Putih Telur

Alchemy
Dalam penelitian ini, silika yang disintesis dari Lapindo lumpur dengan metode sol-gel menggunakan P123-putih telur dan berhasil diterapkan sebagai adsorben ibuprofen.
Maria Ulfa, Anisa Ayu Solikah, Zahra Ayu Fadhilah, Ida Setiarini, Zulfana Qoulan Syadida   +4 more
doaj   +1 more source

Metal-Organic Framework MIL-53(Fe) as an Adsorbent for Ibuprofen Drug Removal from Aqueous Solutions: Response Surface Modeling and Optimization

Journal of Chemistry, 2019
Ibuprofen contamination from water sources has been increasingly alarming due to its environmentally accumulative retention; however, the strategies for ibuprofen-containing water treatment are still an enormous challenge.
Duyen Thi Cam Nguyen, Hanh Thi Ngoc Le, Trung Sy Do, Van Thinh Pham, Dai Lam Tran, Van Thi Thanh Ho, Thuan Van Tran, Duy Chinh Nguyen, Trinh Duy Nguyen, Long Giang Bach, Huynh Ky Phuong Ha, Van Thuan Doan   +11 more
doaj   +1 more source

Comparative effectiveness of drugs used to constrict the patent ductus arteriosus: a secondary analysis of the PDA-TOLERATE trial (NCT01958320). [PDF]

, 2019
ObjectiveTo evaluate the effectiveness of drugs used to constrict patent ductus arteriosus (PDA) in newborns < 28 weeks.MethodsWe performed a secondary analysis of the multi-center PDA-TOLERATE trial (NCT01958320).
Aucott, Susan W, Bulbul, Ali, Carey, William A, Clyman, Ronald I, Derrick, Matthew, Dong, Lawrence, Erdeve, Omer, Farooqi, Aijaz, Hassinger, Denise C, Hayashi, Madoka, Heuchan, Anne Marie, Håkansson, Stellan, Kaempf, Joseph, Katheria, Anup, Kimball, Amy, Leone, Tina, Liebowitz, Melissa, Lindqvist, Johanna, Nelson, Kelly, Perez, Jorge, Sankar, Meera, Sauberan, Jason, Serize, Arturo, Singh, Jaideep, Wickremasinghe, Andrea, Wolf, Ilene Sue   +25 more
core   +1 more source

Epidemiology of non-steroidal anti-inflammatory drugs consumption in Spain. The MCC-Spain study [PDF]

, 2018
This work was partially funded by the “Accion Transversal del Cancer”, approved on the Spanish Ministry Council on the 11th October 2007; The Instituto de Salud Carlos III-FEDER [PI08/1770, PI08/0533, PI08/1359, PI09/00773-Cantabria, PI09/01286-León ...
De Pedro, M., Dierssen Sotos, T., Fernández Tardón, Guillermo, Gómez Acebo, I., Tardón García, Adonina   +4 more
core   +2 more sources

Accelerating Discovery of Organic Molecular Crystals via Materials Informatics and Autonomous Experiments

Advanced Intelligent Discovery, EarlyView.
Materials informatics and autonomous experimentation are transforming the discovery of organic molecular crystals. This review presents an integrated molecule–crystal–function–optimization workflow combining machine learning, crystal structure prediction, and Bayesian optimization with robotic platforms.
Takuya Taniguchi, Kazuki Ishizaki, Ryo Fukasawa   +2 more
wiley   +1 more source