Results 21 to 30 of about 6,728 (201)

Investigating the analgesic effects of combined diphenhydramine and dipyrone in mice [PDF]

Veterinary and Comparative Biomedical Research
Pain relief is a crucial aspect of modern surgery. The analgesic used should possess strong analgesic properties, a rapid onset of action, and minimal side effects to effectively reduce pain during and after surgical procedures. Therefore, the aim of the
Mostafa Kalantari, Firouz Faedmaleki, Arya Soneishargh   +2 more
doaj   +1 more source

2-Arylpropionic Acid Pyrazolamides as Cannabinoid CB2 Receptor Inverse Agonists Endowed with Anti-Inflammatory Properties

Pharmaceuticals, 2022
Among the most recent proposals regarding the mechanism of action of dipyrone, the modulation of cannabinoid receptors CB1 and CB2 appears to be a promising hypothesis.
Daniela R. de Oliveira, Rodolfo C. Maia, Patrícia R. de Carvalho França, Patrícia D. Fernandes, Gisele Barbosa, Lídia M. Lima, Carlos A. Manssour Fraga   +6 more
doaj   +1 more source

A novel disposable electrochemical microcell: construction and characterization [PDF]

, 2008
An alternative technique for the fabrication of disposable electrochemical microcells containing working, reference and auxiliary electrodes on a single device is reported.
BERTOTTI, Mauro, DANIEL, Daniela, FERREIRA, Humberto E. A., RICHTER, Eduardo M.   +3 more
core   +1 more source

The Ionic Associate of Metamizole as an Electrode-Active Component of a PVC Plasticized Membrane Electrode

Chemosensors, 2022
The technology for manufacturing a film membrane of the metamizole-selective electrode containing ion associate metamizole-octadecylammonium ODAH+MT− as an electrode active component (EAC) has been proposed. The main potentiometric characteristics of the
Sarizhat D. Tataeva, Kurban E. Magomedov, Ruslan Z. Zeynalov, Naida D. Baygishieva, Viktorya S. Magomedova, Alina A. Rabadanova, Farid F. Orudzhev   +6 more
doaj   +1 more source

Importance of MS selectivity and chromatographic separation in LC-MS/MS-based methods when investigating pharmaceutical metabolites in water. Dipyrone as a case of study. [PDF]

, 2012
Pharmaceuticals are emerging contaminants of increasing concern because of their presence in the aquatic environment and potential to reach drinking-water sources.
GRACIA LOR, EMMA, Hernandez, Felix, Ibáñez, Maria, Sancho, Juan V   +3 more
core   +2 more sources

Uso de analgésicos em pacientes com insuficiência renal [PDF]

, 2014
BACKGROUND AND OBJECTIVES: The use of drugs to treat renal failure has particularities due to pharmacokinetic changes present in such population. This study aimed at supplying subsidies for a rational choice of analgesics to be used in patients with ...
Nunes, Marcelo Henrique Gomes, Sakata, Rioko Kimiko   +1 more
core   +1 more source

Effects of dipyrone on the digestive tract

Brazilian Journal of Medical and Biological Research, 2019
Dipyrone (metamizole), acting through its main metabolites 4-methyl-amino-antipyrine and 4-amino-antipyrine, has established analgesic, antipyretic, and spasmolytic pharmacological effects, which are mediated by poorly known mechanisms.
E.F. Collares, L.E.A. Troncon
doaj   +1 more source

Evidence of the effect of dipyrone on the central nervous system as a determinant of delayed gastric emptying observed in rats after its administration

Brazilian Journal of Medical and Biological Research, 2003
Dipyrone administered intravenously (iv) delays gastric emptying (GE) in rats. The objectives of the present study were to assess: 1) the effect of the dose of dipyrone and time after its iv administration on GE in rats, 2) the effect of subdiaphragmatic
E.F. Collares, A.M. Vinagre
doaj   +1 more source

Adverse drug events in a paediatric intensive care unit: a prospective cohort [PDF]

, 2013
Objectives: To describe adverse drug events (ADEs) in children under intensive care, identify risk factors and tools that can detect ADEs early, and the impact on length of stay (LOS).Design: A prospective observational study.Setting: Paediatric ...
Alonso, Carolina F. R., Araujo, Orlei Ribeiro, Arduini, Rodrigo G., Shibata, Audrey R. O., Silva, Dafne C. B., Troster, Eduardo J.   +5 more
core   +2 more sources

Inhibition of human neutrophil oxidative burst by pyrazolone derivatives [PDF]

, 2006
The risk of agranulocytosis associated with the use of pyrazolone drugs at therapeutical doses and for short periods of time has been considered to be very low.
Costa, David, Fernandes, Eduarda, Lima, José L. F. C., Marques, A. P., Reis, R. L.   +4 more
core   +1 more source