Investigating the analgesic effects of combined diphenhydramine and dipyrone in mice [PDF]
Pain relief is a crucial aspect of modern surgery. The analgesic used should possess strong analgesic properties, a rapid onset of action, and minimal side effects to effectively reduce pain during and after surgical procedures. Therefore, the aim of the
Mostafa Kalantari +2 more
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Association of analgesic pharmacological effect with pain site in pediatric oncology patients [PDF]
BackgroundCancer in children and adolescents is frequently associated with pain, which is one of the most common and distressing symptoms reported by patients. Effective pain management remains a major concern for healthcare teams.
Flavia Carvalho Marotta +6 more
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Effect of the GABA B agonist baclofen on dipyrone-induced delayed gastric emptying in rats [PDF]
Dipyrone administered intravenously (iv) or intracerebroventricularly (icv) delays gastric emptying (GE) in rats. Gamma-aminobutyric acid (GABA) is the most potent inhibitory neurotransmitter of the central nervous system.
E.F. Collares, A.M. Vinagre
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Cannabinoid Effects of Metamizol/Dipyrone: A Possible Second Life in Pediatric Anesthesia for a Vintage Drug [PDF]
Background: Metamizol (dipyrone) is a widely used analgesic and antipyretic drug in several European countries, particularly for postoperative pain management in both adult and pediatric populations.
Alessandro Vittori +10 more
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Cross-Reactivity: a Case of Paracetamol-Induced Generalized Bullous Fixed Drug Eruption Followed by Dipyrone-Induced Fixed Drug Eruption [PDF]
Yuanyuan Wang,1,* Huan Xue,2,* Hejun Dai,1 Lianjuan Yang1 1Department of Medical Mycology, Center of Infectious Skin Diseases, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of China; 2Department
Wang Y, Xue H, Dai H, Yang L
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The analgesic efficacy of xylazine and dipyrone in hydrogen peroxide-induced oxidative stress in chicks [PDF]
The effect of oxidative stress–induced by hydrogen peroxide (H2O2) on the analgesic effect of xylazine and dipyrone in 7-14 days old chicks was studied, compared with the control group that given plane tap water.
Y.J. Mousa, F.K. Mohammad
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The antipyretic effectiveness of dipyrone in the intensive care unit: A retrospective cohort study.
IntroductionDipyrone (metamizol) is regularly used in critical care for pain and fever treatment, especially in Germany and Spain. However, indication for antipyretic therapy in critically ill patients is currently unclear and data for both the risk and ...
Hans-Jörg Gillmann +3 more
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Evaluation of ketorolac compared to ketorolac plus dipyrone in post-operative analgesia of videolaparoscopic cholecystectomy [PDF]
Objectives: To compare the analgesic effect of ketorolac with the association of ketorolac plus dipyrone after videolaparoscpic cholecystectomy and with a placebo group.
Silvia Katlauskas Muraro +2 more
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Introduction: Tonsillectomy is the 2nd most common outpatient surgery performed on children in the United States of America. Its main complication is pain, which varies in intensity from moderate to severe.
Maira Isis S. Stangler +3 more
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Effects of intratesticular injection of zinc-based solution in rats in combination with anti-inflammatory and analgesic drugs during chemical sterilization [PDF]
Aim: Chemical sterilization is a non-surgical method of contraception based on compounds injected into the testis to induce infertility. However, these injections can cause discomfort and pain able to impair the recovery of animals after this treatment ...
Simone Regina Barros de Macedo +7 more
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