Results 11 to 20 of about 6,507 (223)

Effects of dipyrone on the digestive tract [PDF]

open access: yesBrazilian Journal of Medical and Biological Research, 2019
Dipyrone (metamizole), acting through its main metabolites 4-methyl-amino-antipyrine and 4-amino-antipyrine, has established analgesic, antipyretic, and spasmolytic pharmacological effects, which are mediated by poorly known mechanisms.
E.F. Collares, L.E.A. Troncon
doaj   +2 more sources

Antipyretic efficacy and tolerability of oral ibuprofen, oral dipyrone and intramuscular dipyrone in children: a randomized controlled trial

open access: yesSão Paulo Medical Journal
CONTEXT AND OBJECTIVE: Dipyrone is a widely used over-the-counter antipyretic in Latin America, and elsewhere among Latin immigrants. Despite limited evidence, physicians often prescribe oral ibuprofen or intramuscular dipyrone as the most effective ...
Judith Prado   +4 more
doaj   +2 more sources

Dipyrone as pre-emptive measure in postoperative analgesia after tonsillectomy in children: a systematic review

open access: yesBrazilian Journal of Otorhinolaryngology, 2021
Introduction: Tonsillectomy is the 2nd most common outpatient surgery performed on children in the United States of America. Its main complication is pain, which varies in intensity from moderate to severe.
Maira Isis S. Stangler   +3 more
doaj   +2 more sources

Dipyrone and acetaminophen: correct dosing by parents?

open access: yesSão Paulo Medical Journal
CONTEXT AND OBJECTIVE: Several studies in developed countries have documented that a significant percentage of children are given inappropriate doses of acetaminophen and ibuprofen.
João Guilherme Bezerra Alves   +3 more
doaj   +2 more sources

Tepid sponging plus dipyrone versus dipyrone alone for reducing body temperature in febrile children

open access: yesSão Paulo Medical Journal
CONTEXT AND OBJECTIVE: The role of tepid sponging to promote fever control in children is controversial. We did not find any studies reporting on the effectiveness of tepid sponging in addition to dipyrone.
João Guilherme Bezerra Alves   +2 more
doaj   +2 more sources

Tilidine and dipyrone (metamizole) in cold pressor pain: A pooled analysis of efficacy, tolerability, and safety in healthy volunteers

open access: yesClinical and Translational Science, 2021
The cold pressor test (CPT) is widely implemented and offers a simple, experimental acute pain model utilizing cold pain. Previous trials have frequently paired the CPT with opioids in order to investigate the mechanisms underlying pharmacological ...
Julian Kleine‐Borgmann   +6 more
doaj   +2 more sources

Intravenous dipyrone for the acute treatment of episodic tension-type headache: A randomized, placebo-controlled, double-blind study

open access: yesBrazilian Journal of Medical and Biological Research, 2002
Acute headaches are responsible for a significant percentage of the case load at primary care units and emergency rooms in Brazil. Dipyrone (metamizol) is easily available in these settings, being the most frequently used drug. We conducted a randomized,
M.E. Bigal, C.A. Bordini, J.G. Speciali
doaj   +2 more sources

Excess Mortality in Aspirin and Dipyrone (Metamizole) Co‐Medicated Patients With Cardiovascular Disease: A Nationwide Study

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Pain is a major issue in our aging society. Dipyrone (metamizole) is one of the most frequently used analgesics. Additionally, it has been shown to impair pharmacodynamic response to aspirin as measured by platelet function tests.
Amin Polzin   +18 more
doaj   +2 more sources

Investigating the analgesic effects of combined diphenhydramine and dipyrone in mice [PDF]

open access: yesVeterinary and Comparative Biomedical Research
Pain relief is a crucial aspect of modern surgery. The analgesic used should possess strong analgesic properties, a rapid onset of action, and minimal side effects to effectively reduce pain during and after surgical procedures. Therefore, the aim of the
Mostafa Kalantari   +2 more
doaj   +3 more sources

Dipyrone is the preferred nonopioid analgesic for the treatment of acute and chronic pain. A survey of clinical practice in German‐speaking countries [PDF]

open access: yesEuropean Journal of Pain, 2018
PURPOSE Nonopioid analgesics are frequently used for the treatment of acute and chronic pain. Dipyrone is an alternative to NSAIDs and paracetamol, however, data on the frequency of its usage by anaesthesiologists in the perioperative and chronic pain
L. Reist   +5 more
semanticscholar   +2 more sources

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