Results 71 to 80 of about 25,421 (273)

Therapeutic potential of small molecules that block receptor‐induced Kv7/M‐current suppression in neuroprotection, seizures, and pain

open access: yesBritish Journal of Pharmacology, EarlyView.
Receptor‐induced Kv7/M‐current suppression increases neuronal activity and contributes to pathology of several conditions. A new class of Kv7 modulators identified in this study attenuates M‐current suppression and shows therapeutic effects. Abstract Background and Purpose Neuronal Kv7 channels generate low voltage–gated potassium currents known as the
Young Woo Kim   +5 more
wiley   +1 more source

Resolving Micrometre‐Scale Zircon Growth in Silicic Systems by 7 μm LA‐MC‐ICP‐MS U‐Pb Dating: Linking Petrology and Geochronology in Silicic Volcanic and Granitic Rocks from Victoria, Australia

open access: yesGeostandards and Geoanalytical Research, EarlyView.
Key Points 7 μm spot‐diameter LA‐MC‐ICP‐MS analyses yield accurate zircon U‐Pb ages. 1013 Ω amplifier resistors improve low‐signal Pb measurements. Saturn correction protocols minimise down‐hole fractionation effects. We present a systematic evaluation of high spatial‐resolution zircon U‐Pb dating using a Thermo Scientific Neoma multi‐collector ICP‐MS ...
Cristiano Lana, John D. Clemens
wiley   +1 more source

Metamorphism and Metamorphic Rocks

open access: yes, 2013
In the previous chapters, we learned about igneous and sedimentary rocks. This chapter presents some general concepts concerned with the process of metamorphism and the formation of metamorphic rocks. How pressure, temperature, and fluids control metamorphic processes and resulting metamorphic changes are discussed.
openaire   +1 more source

Contact metamorphism on 4 Vesta and the Petersburg polymict eucrite

open access: yes, 2005
P(論文)Using equations for thermal diffusion, we model the temperature profiles in metamorphic aureoles surrounding 1km and 3km diameter spherical intrusions containing eucrite and diogenite magmas in the crust of 4 Vesta.
Buchanan,Paul C., Kaiden,Hiroshi
core   +1 more source

Variable Sr Diffusion and Implications for Rb–Sr Biotite Geochronology

open access: yesJournal of Metamorphic Geology, EarlyView.
ABSTRACT The rubidium–strontium (Rb–Sr) system has a long pedigree as a geochronological tool that relies on the application of an isochron approach. In particular, biotite contains strongly radiogenic Rb–Sr isotopes, and thus can yield meaningful crystallisation or cooling ages via this approach. However, the response of the Rb–Sr system in biotite to
Riley Rohrer   +4 more
wiley   +1 more source

Mineralogy and metabasites formation conditions from ophiolite association at northern slope of Kuznetsk Alatau

open access: yesЛитосфера, 2017
The ophiolites of the northern slope of the Kuznetsk-Alatau Ridge are the most representative fragments of the sub-oceanic crust in the region. In this article, we present the results of a study of the metabasites from ophiolite paragenesis of the ...
N. A. Dugarova   +3 more
doaj   +1 more source

On ultrahigh-temperature crustal metamorphism

open access: yes, 2008
Ultrahigh-temperature (UHT) metamorphism is the most thermally extreme type of crustal metamorphism, with the crust capable of withstanding temperatures ≥ 900 °C.
Kelsey, D.
core   +1 more source

Mineral reaction and deformation in Plagioclase-Olivine composites : an experimental study [PDF]

open access: yes, 2004
Deformation and metamorphism of rocks are fundamentally interrelated but the ways in which processes of reaction and deformation mutually influence each other are still poorly understood in natural rocks.
Ronde, Almar A. de
core   +1 more source

P–T Modelling Constrains the Depth of Emplacement of the Porto Azzurro Pluton and Implies Minor Exhumation Caused by the Zuccale Fault (Island of Elba, Italy)

open access: yesJournal of Metamorphic Geology, EarlyView.
ABSTRACT Understanding the pressure of emplacement of granitic intrusions is crucial to understanding the exhumation history of plutons and constraining the tectonic setting of magma emplacement. However, P–T and geochronological constraints from exhumed plutons are often characterized by large uncertainties, especially in shallow crustal settings with
Samuele Papeschi   +4 more
wiley   +1 more source

Metamorphic Coverage

open access: yesCoRR
Metamorphic testing is a widely used methodology that examines an expected relation between pairs of executions to automatically find bugs, such as correctness bugs. We found that code coverage cannot accurately measure the extent to which code is validated and mutation testing is computationally expensive for evaluating metamorphic testing methods. In
Jinsheng Ba   +2 more
openaire   +2 more sources

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