Results 81 to 90 of about 112,509 (371)

Characterization of BRCA1‐Associated Protein‐1 (BAP1) Aggregation Properties Induced by Cancer‐Associated Mutations

open access: yesChemBioChem, EarlyView.
BAP1 is a master regulator of oncogenesis with many cancer‐associated mutations within its N‐terminal ubiquitin C‐terminal hydrolase (UCH) domain. We analytically demonstrated that BAP1‐UCH harboring the N78S, C91W, F81V, and G128R mutations aggregate into amyloid fibrils following a secondary nucleation aggregation model.
Li‐Ching Hsiao   +6 more
wiley   +1 more source

Amphibole: A major carrier of helium isotopes in crustal rocks [PDF]

open access: yes, 2016
The first evidence for a specific role of amphiboles in He isotope balance of crustal rocks was presented in early contributions by Gerling et al. (1971, 1976).
A.B. Verchovsky   +65 more
core   +1 more source

Conserved Phosphorylation of the Myosin1e TH1 Domain Impacts Membrane Association and Function in Yeast and Worms

open access: yesCytoskeleton, EarlyView.
ABSTRACT Cells have an intrinsic ability to rapidly respond to environmental change to regulate cell cycle progression and membrane organisation, thereby affecting cell growth and division. The actin cytoskeleton is a highly dynamic complex of proteins that can rapidly reorganise to change the growth pattern of a cell.
Holly R. Brooker   +7 more
wiley   +1 more source

Tectono-metamorphic evolution and timing of the melting processes in the Svecofennian Tonalite-Trondhjemite Migmatite Belt: An example from Luopioinen, Tampere area, southern Finland [PDF]

open access: yesBulletin of the Geological Society of Finland, 1999
The Svecofennian Orogen is in southern Finland characterized by two major migmatite belts. These are the so-called Granite Migmatite Belt, in which Kfs-rich leucosomes predominate, and the Tonalite-Trondhjemite Migmatite Belt, which is characterized by ...
H. Mouri, K. Korsman, H. Huhma
doaj   +1 more source

Trace element and isotope constraints on crustal anatexis by upwelling mantle melts in the North Atlantic Igneous Province: an example form the Isle of Rum, NW Scotland [PDF]

open access: yes, 2009
Sr and Nd isotope ratios, together with lithophile trace elements, have been measured in a representative set of igneous rocks and Lewisian gneisses from the Isle of Rum in order to unravel the petrogenesis of the felsic rocks that erupted in the early ...
Ellam, R.M.   +5 more
core   +1 more source

The C‐Terminal Regions of TRAK Proteins Contain MIRO‐Independent Mitochondrial Localization Domains

open access: yesCytoskeleton, EarlyView.
ABSTRACT Current models suggest that MIRO GTPases anchor cytoskeletal motors to the mitochondrial outer membrane (MOM). However, our previous findings indicate that the unconventional myosin, MYO19, interacts with MIRO weakly and that a MIRO‐independent MOM‐localizing domain interacts more tightly with the MOM.
Lili Mitchell   +4 more
wiley   +1 more source

La terra dove nulla scompare per sempre [PDF]

open access: yesKaiak, 2015
The traditional cultures of Native American tribes and populations have been humbled for a very long time by the WASP dominant vision of the US destiny. Through particular laws like the sadly well-known Indian Removal Act (1830), the
Giuseppe Russo
doaj  

XXIV ALLRUSSIA YOUTH CONFERENCE ON STRUCTURE OF LITHOSPHERE AND GEODYNAMICS, IRKUTSK, RUSSIA, APRIL 19–24, 2011

open access: yesГеодинамика и тектонофизика, 2015
The information on the XXIV AllRussia youth conference on structure of lithosphere and geodynamics is presented. It was held on April 19–24, 2011 at the Institute of the Earth’s Crust, Irkutsk. The scope of conference is presented.
Victoria A. Khak
doaj   +1 more source

Structural analysis and metamorphism of Palaeoproterozoic metapelites in the Seinäjoki-Ilmajoki area, western Finland [PDF]

open access: yesBulletin of the Geological Society of Finland, 1999
The Palaeoproterozoic Svecofennian bedrock of the Seinäjoki-Ilmajoki area, western Finland, is largely composed of porphyroblastic metapelites. In the area, the regional metamorphic grade increases towards the southwest.
H. Mäkitie
doaj   +1 more source

Deciphering depositional controls and evolution of a lacustrine supradetachment basin through facies analysis: Gördes Basin, Western Türkiye

open access: yesThe Depositional Record, EarlyView.
The lacustrine Gördes Supradetachment Basin was developed along the Simav detachment fault during postorogenic extension in the north of the Menderes Massif in western Anatolia. The basin‐fill succession is represented by alluvial fan, Gilbert‐type delta, shoal‐water delta, foreshore, shoreface, offshore‐transition and peat‐forming mire deposits.
Ayhan Ilgar   +5 more
wiley   +1 more source

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