Results 91 to 100 of about 137,582 (366)

SP1‐Mediated Glycolytic Reprogramming Promotes Tumorigenesis and Progression in Pancreatic Cancer

Advanced Science, EarlyView.
Laser capture microdissection‐based proteomics of pancreatic intraepithelial neoplasia (PanIN) identifies specificity protein 1 (SP1) as a key driver of tumorigenesis and progression in pancreatic cancer through glycolytic remodeling. SP1 enhances aerobic glycolysis by transcriptionally activating 6‐phosphofructo‐2‐kinase/fructose‐2,6‐bisphosphatase ...
Hexing Hang, Mengyu Yu, Linxi Zhu, Neng Tang, Xiao Fu, Zhenghua Cai, Minghao Yan, Yi Chen, Lei Yang, Jianzhuang Wu, Jiatong Tang, Yu Xie, Qi Li, Xu Fu, Liang Mao, Jun Chen, Fanqing Meng, Bo Kong, Xiaodong Han, Chao Yan, Yudong Qiu, Hao Cheng   +21 more
wiley   +1 more source

A case of carcinoma of the breast with metaplasia to chondrosarcoma: Light microscopic and immunohistochemical features [PDF]

Archive of Oncology, 2003
The breast carcinomas with metaplasia are rare neoplasms showing both carcinomatous and sarcomatous elements. We described clinical behavior radiology findings and pathological features in case of breast carcinoma with heterologous chondrosarcomatoid ...
Fenyvesi Attila
doaj   +1 more source

Myeloid metaplasia of the breast

Annals of Oncology, 2001
Hereby, we present the case of a 50-year-old woman with 5-year history of chronic idiopathic myelofibrosis who was referred to our institution after she had noted a lump in the breast. Histological examination of the lesion removed from her left breast yielded the diagnosis of extramedullary hematopoiesis in the breast.
M. Bracko, T. Cufer
openaire   +3 more sources

Spasmolytic Polypeptide-Expressing Metaplasia and Intestinal Metaplasia: Time for Reevaluation of Metaplasias and the Origins of Gastric Cancer [PDF]

Gastroenterology, 2010
Gastric adenocarcinoma of the intestinal type is believed to develop through a series of histopathologic stages, originally described by Correa, that include chronic gastritis, gastric atrophy, intestinal metaplasia, dysplasia and finally cancer (1).
Ki Taek Nam, Timothy C. Wang, James R. Goldenring, Nicholas A. Wright, Jason C. Mills   +4 more
openaire   +4 more sources

Prevalence of Helicobacter pylori in patients with gastro-oesophageal reflux disease : systematic review. [PDF]

, 2003
Objectives: To ascertain the prevalence of Helicobacter pylori in patients with gastro-oesophageal reflux disease and its association with the disease.
Childs, S., Hungin, A. P. S., Raghunath, A., Wooff, D.   +3 more
core   +2 more sources

Dual‐Pedicle Tissue‐Engineered Trachea Promotes Biomimetic Cartilaginous Framework, Vascularization, and Epithelial Lining for Long‐Segment Tracheal Reconstruction

Advanced Science, EarlyView.
Overcoming the limitations of conventional grafts, a biomimetic trachea with two independent vascular pedicles enables rapid integration and sustained patency. This approach markedly improves survival rates, restores the epithelial barrier, and promotes regenerative pathways, presenting a transformative paradigm for clinical application.
Ziming Wang, Yuming Wang, Zihao Chen, Erji Gao, Liang Guo, Juanjuan Li, Siqiang Zheng, Jiaoyu Yi, Zhe‐Sheng Chen, Bo Tao   +9 more
wiley   +1 more source

Research advancements and evaluation of multifactor‐induced murine models for gastric cancer

Animal Models and Experimental Medicine, EarlyView.
Murine models for gastric cancer. Abstract As one of the most prevalent gastrointestinal malignancies in humans, gastric cancer (GC) is often detected at an advanced stage, resulting in a poor prognosis and ranking it the fifth leading cause of cancer‐related deaths.
Yiqing Wang, Liang Zhang, Weixu Feng, Wanfeng Liu, Xiangyang Xue, Shiyu Feng   +5 more
wiley   +1 more source

Taking Down the Primary Cilium: Pathways for Disassembly in Differentiating Cells

BioEssays, EarlyView.
Primary cilia are developmentally essential subcellular signaling compartments. However, many differentiated cells lack primary cilia, and cilia disassembly in these tissue contexts has been largely overlooked. We highlight several pathways for primary cilia loss and examine how changes in ciliation states could contribute to diverse pathologies ...
Carolyn M. Ott, Saikat Mukhopadhyay
wiley   +1 more source

The Fibroblast Landscape in Stomach CarcinogenesisSummary

Cellular and Molecular Gastroenterology and Hepatology
Numerous recent studies using single cell RNA sequencing and spatial transcriptomics have shown the vast cell heterogeneity, including epithelial, immune, and stromal cells, present in the normal human stomach and at different stages of gastric ...
Ela W. Contreras-Panta, Eunyoung Choi, James R. Goldenring   +2 more
doaj   +1 more source

Spindle Cell Metaplastic Breast Cancer: Case Report

Archives of Clinical and Experimental Surgery, 2013
Objective: Spindle cell metaplastic breast cancer is a subtype of breast cancer, which is very rare and difficult to diagnose. There is no specific symptom in differentiation from the other breast cancers.
Dursun Ozgur Karakas, Ahmet Ziya Balta, Yavuz Ozdemir, Ali Ilker Filiz, Ergun Yucel, Ufuk Berber   +5 more
doaj   +1 more source