Gastric cancer is the leading cause of death in Italian adult patients with common variable immunodeficiency [PDF]
An increased prevalence of malignant lymphoma and of gastric cancer has been observed in large cohorts of patients with common variable immunodeficiency (CVID), the most frequently symptomatic primary immunodeficiency. Surveillance strategies for cancers
Agostini, Carlo +11 more
core +3 more sources
Endogenous glucocorticoids prevent gastric metaplasia by suppressing spontaneous inflammation
In the stomach, chronic inflammation causes metaplasia and creates a favorable environment for the evolution of gastric cancer. Glucocorticoids are steroid hormones that repress proinflammatory stimuli, but their role in the stomach is unknown.
Jonathan T. Busada +5 more
semanticscholar +1 more source
H. pylori-associated pathologic findings among Alaska native patients
Helicobacter pylori infection is common among Alaska native (AN) people, however scant gastric histopathologic data is available for this population. This study aimed to characterise gastric histopathology and H. pylori infection among AN people.
Leisha Diane Nolen +9 more
doaj +1 more source
New European guidelines for the management of patients with precancerous changes in the stomach
Aim of the review: to analyze the current aspects of the management of patients with precancerous changes in the stomach, as outlined in the new MAPS II European recommendations.Basic provisions.
V. V. Tsukanov +3 more
doaj +1 more source
Expression of PIK3CA mutant E545K in the mammary gland induces heterogeneous tumors but is less potent than mutant H1047R. [PDF]
The phosphoinositide 3-kinase (PI3K) signaling cascade is a key mediator of cellular growth, survival and metabolism and is frequently subverted in human cancer.
Bentires-Alj, M +8 more
core +2 more sources
Metaplastic Sarcomatoid Carcinoma of the Breast. Case Report
Metaplastic Tumors of the mammary gland are infrequent. The diagnosis should be based on studies of hematoxylin and eosin, confirmed by inmunohistochemical markers.
Javier Martínez Navarro +3 more
doaj +2 more sources
Comparative morphological characteristics of helicobacter pylori and autoimmune gastritis
Objective: to conduct a comparative morphological analysis of helicobacter pylori (H. pylori) and autoimmune gastritis and to determine the significant morphological criteria for differential diagnosis.Materials and methods.
N. V. Pachuashvili +2 more
doaj +1 more source
Transcribed ultraconserved noncoding RNAs (T-UCR) are involved in Barrett's esophagus carcinogenesis. [PDF]
Barretts esophagus (BE) involves a metaplastic replacement of native esophageal squamous epithelium (Sq) by columnar-intestinalized mucosa, and it is the main risk factor for Barrett-related adenocarcinoma (BAc).
Baffa, R +17 more
core +4 more sources
Metaplasia of Chondrocytes into Osteoblasts
Hypertrophic chondrocytes, commonly considered as terminal cells responsible for apoptotic elimination in endochondral osteogenesis, have the potential to switch their metabolic role and enter osteoblastic differentiation, based on histochemical, immunohistochemical, biochemical and cytological analysis.
Krzysztof H Włodarski +2 more
openaire +2 more sources
Local lung hypoxia determines epithelial fate decisions during alveolar regeneration. [PDF]
After influenza infection, lineage-negative epithelial progenitors (LNEPs) exhibit a binary response to reconstitute epithelial barriers: activating a Notch-dependent ΔNp63/cytokeratin 5 (Krt5) remodelling program or differentiating into alveolar type II
Brumwell, Alexis N +13 more
core +1 more source

