Results 81 to 90 of about 100,911 (305)

Mice lacking NF-κB1 exhibit marked DNA damage responses and more severe gastric pathology in response to intraperitoneal tamoxifen administration [PDF]

, 2017
Tamoxifen (TAM) has recently been shown to cause acute gastric atrophy and metaplasia in mice. We have previously demonstrated that the outcome of Helicobacter felis infection, which induces similar gastric lesions in mice, is altered by deletion of ...
A Iannetti, A Rehemtulla, AB Rogers, B Bang, C Van Themsche, CA Duckworth, CY Wang, DH Phillips, DY Graham, F Liu, J Burclaff, JB Saenz, JG Fox, JM Williams, K Ijiri, M Sigal, M Yu, MD Burkitt, MD Burkitt, MD Burkitt, N Novac, P Correa, R Hu, R Poltz, SMC Przemeck, WJ Huh, X Wang, Y Wang, YJ Merga   +28 more
core   +1 more source

Patient‐derived xenograft models in pan‐cancer: From bench to clinic

Interdisciplinary Medicine, EarlyView.
Abstract Patient‐derived xenograft (PDX) models provide a robust preclinical platform that preserves the genetic and phenotypic heterogeneity of patient tumors while mirroring their tumor genetic characteristics, which retain malignant cells and the tumor pathological structure, making them valuable for studying tumor progression and developing ...
Jiatong Li, Ao Gu, Nannan Tang, Gokhan Zengin, Meng‐Yao Li, Yingbin Liu   +5 more
wiley   +1 more source

Combined histological and DNA methylome profiling approaches may provide insights into the pathophysiology of ovarian endometriomas

Reproductive Medicine and Biology, 2023
Purpose To test the theory that invaginated ovarian surface epithelium and endometrial implants on the ovary form ovarian endometriomas. Methods Adhesion sites of ovarian endometrioma on the peritoneum and consecutive ovarian endometrioma cyst wall ...
Ryo Maekawa, Yoshiaki Ota, Ikuko Ota, Yumiko Mihara, Hitomi Takasaki, Shun Sato, Isao Tamura, Yuichiro Shirafuta, Masahiro Shinagawa, Taishi Fujimura, Amon Shiroshita, Toshihide Yoneda, Mai Kawamoto‐Jozaki, Fuka Matsui, Toshiaki Taketani, Norihiro Sugino   +15 more
doaj   +1 more source

Splenectomy in Myeloid Metaplasia

Annals of Surgery, 1978
A retrospective review of 19 patients with documented myeloid metaplasia undergoing, elective splenectomy during the past ten years at the Peter Bent Brigham Hospital is presented. The primary indications for splenectomy in 17 of these 19 were either hypersplenism or symptomatic splenomegaly.
D S Rosenthal, E B Cabot, M F Brennan, Richard Wilson   +3 more
openaire   +4 more sources

Prevalence of Pancreaticobiliary Maljunction and High Confluence of the Pancreaticobiliary Ducts: True Incidence of Gallbladder Cancer

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background Although pancreaticobiliary maljunction (PBM) is associated with a high incidence of biliary cancer, it often goes undiagnosed. This means that the true prevalence of PBM and the incidence of biliary cancer are unknown. High confluence of the pancreaticobiliary ducts (HCPBD) may be an intermediate PBM variant, though reports are ...
Shintaro Shirai, Kenitiro Kaneko, Shoko Kato, Remi Kondo, Takaaki Osawa, Yasuyuki Fukami, Tsuyoshi Sano   +6 more
wiley   +1 more source

Gastritis crónica. Correlación de la clasificación de Sydney con el diagnóstico endoscópico Chronic gastritis. Correlation of the Sydney classification with endoscopic diagnosis

Revista Colombiana de Cirugía, 2004
El concepto de gastritis crónica siempre ha sido motivo de controversia. Con el propósito de eliminar confusiones diagnósticas se crea en Sydney (Australia) un sistema de clasificación y gradación (Sistema Sydney).
Juan José Gaviria Jiménez, Mario Melguizo Bermúdez   +1 more
doaj  

Ileostomy Adenocarcinoma : a case report [PDF]

, 2004
Proctocolectomy is the standard treatment for patients suffering from ulcerative colitis which is long-standing, refractory to pharmacotherapy or otherwise associated with complications.
Abela, Joetienne, LaFerla, Godfrey, Szczepanski, Marcin J.   +2 more
core  

A case of Barrett's oesophagus in pernicious anaemia: acid is not the only culprit! [PDF]

, 2016
A 46-year-old female presented at our department with the onset of episodic dyspeptic symptoms, mainly postprandial fullness and bloating, as well as paresthesia.
Annibale, Bruno, Carabotti, Marilia, Lahner, Edith, Severi, Carola   +3 more
core   +1 more source

Cow's milk protein allergy with protein‐losing enteropathy under the scope

JPGN Reports, EarlyView.
ABSTRACT Objectives Cow's milk protein allergy (CMPA) is very frequent in infants. Presentation is variable, and symptoms fluctuate in intensity. Diagnosis can be challenging as it is mostly clinical. In severe cases, patients can present with anasarca secondary to protein‐losing enteropathy (PLE).
Morgane Thorens‐Borgeat, Géraldine Blanchard‐Rohner, Salim Ramadan, Jean‐Christophe Caubet, Laetitia‐Marie Petit, Valerie McLin, Anne‐Laure Rougemont   +6 more
wiley   +1 more source

bak deletion stimulates gastric epithelial proliferation and enhances Helicobacter felis-induced gastric atrophy and dysplasia in mice [PDF]

, 2015
Helicobacter infection causes a chronic superficial gastritis that in some cases progresses via atrophic gastritis to adenocarcinoma. Proapoptotic bak has been shown to regulate radiation-induced apoptosis in the stomach and colon and also susceptibility
Abuderman, A A, Burkitt, M D, Duckworth, C A, O'Reilly, L A, Pritchard, D M, Williams, J M   +5 more
core   +1 more source