Results 101 to 110 of about 401,460 (242)

The diagnostic value of endoscopic score based on acetic acid-enhanced narrow-band imaging for gastric intestinal metaplasia

Zhongguo Linchuang Yixue
ObjectiveTo explore the diagnostic value of endoscopic grading of gastric intestinal metaplasia (EGGIM) score under acetic acid-enhanced narrow band imaging (AA-NBI) observation mode for gastric intestinal metaplasia (GIM). MethodsA total of 120 patients
Chen XU, Zhengyang LI, Haiyan WANG, Yuhao WANG, Xuanguang YE, Miao JIANG   +5 more
doaj   +1 more source

Early Gastric Cancer Detected During 15‐year Surveillance After Ménétrier Disease Remission and Successfully Treated With Endoscopic Submucosal Dissection: A Case Report

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Ménétrier disease (MD) was diagnosed based on hypoalbuminemia and giant gastric folds extending from the body to the fundus in a woman in her 70s. A serum anti‐Helicobacter pylori antibody test and urea breath test yielded negative results.
Takaaki Shamoto, Hideko Yamamoto, Takehito Naito, Masahiro Yamada, Hirotaka Suzuki, Emiko Hida, Takafumi Yamamoto, Yoshifumi Arai, Hiroshi Matsubara   +8 more
wiley   +1 more source

Towards deep-learning based detection and quantification of intestinal metaplasia on digitized gastric biopsies: a multi-expert comparative study

Scientific Reports
Current gastric cancer (GCa) risk systems are prone to errors since they evaluate a visual estimation of intestinal metaplasia percentages in histopathology images of gastric mucosa to assign a risk.
Fabian Cano, Mauricio Caviedes, Andres Siabatto, Jesus Villarreal, Jose Quijano, Álvaro Bedoya-Urresta, Marino Coral Bedoya, Yomaira Yepez Caicedo, Angel Cruz-Roa, Fabio A. González, Satish E. Viswanath, Eduardo Romero   +11 more
doaj   +1 more source

A Cell Marker Atlas to Distinguish Metaplastic Transitions in Human Esophagus and Stomach

Cellular and Molecular Gastroenterology and Hepatology
Metaplasia is an adaptative response to injury and inflammation and can be a precursor to dysplasia and cancer. Metaplasia in the esophagus, termed Barrett’s esophagus, is the replacement of the stratified squamous epithelium by glandular tissue ...
Karen J. Dunbar, Su-Hyung Lee, Yoonkyung Won, Emily M. Esquea, Jeong Yun Yang, Daniel O. Kechele, Sandra Ryeom, Julian A. Abrams, Frank D. McKeon, James M. Wells, Micheal Quante, Eunyoung Choi, Jianwen Que, Timothy C. Wang, Anil K. Rustgi, James R. Goldenring   +15 more
doaj   +1 more source

Third Space Endoscopic Therapies for Benign Motility Disorders: A Narrative Review

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives To review the evidence base, evolution, outcomes, adverse events (AEs), and management for third‐space endoscopy (TSE) procedures for management of benign motility disorders. Methods This review examines TSE procedures for motility disorders, reviewing the current available techniques, success, outcomes, and long‐term outcomes from ...
Sanjana Bhagwat, Amol Bapaye
wiley   +1 more source

Submucosal Invasion and Ulceration in Early Gastric Cancer Affect Mucosal Impedance

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives To investigate early changes in gastric cancers that are difficult to evaluate using endoscopic imaging through the assessment of mucosal impedance (MI) in endoscopic submucosal dissection (ESD) specimens. Methods In this single‐center prospective cohort study, we included patients who underwent ESD for early gastric cancer (EGC ...
Kaede Miyashiro, Yohei Sawada, Hidezumi Kikuchi, Shintaro Goto, Tadashi Yoshizawa, Saki Nakano, Taka Asari, Tatsuta Tetsuya, Daisuke Chinda, Hirotake Sakuraba   +9 more
wiley   +1 more source

Synchronous and Metachronous Multiple Gastric Epithelial Neoplasms Detected During Index Evaluation and Post‐Endoscopic Submucosal Dissection Surveillance: A Descriptive Comparison

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives We compared synchronous and metachronous gastric tumors detected during index evaluation and surveillance after endoscopic submucosal dissection (ESD), focusing on Kimura‐Takemoto O‐3 atrophy. Helicobacter pylori eradication history and the neutrophil‐to‐lymphocyte ratio (NLR) were exploratory.
Tomokazu Yoshio, Shuhei Fukunaga, Tomoyuki Nakane, Shinpei Minami, Tomonori Cho, Kozo Tsuruta, Hiroshi Tanaka, Ryousuke Gotou, Yusei Watanabe, Michita Mukasa, Miwa Sakai, Takumi Kawaguchi, Hidetoshi Takedatsu   +12 more
wiley   +1 more source

Tripterine Liposome Exerts Antitumor and Immunomodulatory Effects in Pancreatic Ductal Adenocarcinoma

MedComm, Volume 7, Issue 10, October 2026.
Tripterine liposome (TP‐lipo) exerts anti‐pancreatic ductal adenocarcinoma (PDAC) effects through direct suppression of tumor cells and modulation of the tumor microenvironment (TME). TP‐lipo induces apoptosis and inhibits the clonogenicity, migration, and invasion of KPC cells in vitro.
Lirui Tang, Yi Lin, Xueqin Jiang, Xiaohe Tian, Giuseppe Battaglia, Yuquan Wei, Wenshuang Wu, Xuemei He, Xiawei Wei   +8 more
wiley   +1 more source

Small adenocarcinomas of the esophagogastric junction: association with intestinal metaplasia and dysplasia

, 2002
OBJECTIVES: Intestinal metaplasia in Barrett’s esophagus predisposes to esophageal adenocarcinoma. Intestinal metaplasia of the cardia is a common finding in persons without cancer. Many adenocarcinomas of the esophagogastric junction are large enough to
Cameron, Alan J, Souto, Enrico O, Smyrk, Thomas C   +2 more
core   +1 more source

Efficacy and Safety of Elagolix Versus Dienogest for Treatment of Moderate‐to‐Severe Endometriosis Pain: A Phase III, Multicentric, Double‐Blind, Active‐Controlled, Non‐Inferiority Study

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 11, Page 2025-2034, October 2026.
ABSTRACT Objective To compare the efficacy, safety and tolerability of elagolix with dienogest in women with moderate‐to‐severe endometriosis‐associated pain. Design A multicentre, double‐blind, double‐dummy, randomised, parallel‐group, active‐controlled, non‐inferiority phase III study. Setting Nineteen clinical centres across India.
Sneha Bhoir, Jaldhara Patel, Tushar Palve, Mrinal Kanti Dash, Sweety Saigal, Gourisankar Kamilya, Shalini Srivastava, Kartikbhai Savalia, Tanusree Gupta, Deepa Choudhary, Manohar Rangaswamy, Vidya V Bhatt, Neena Gupta, Malathi Ponnuru, Parul Shah, Apurva Shetty, Shruti Saha, Reshma Quadros, Sucheta Pandit, Dipak Patil, Piyush Patel, Pravin Ghadge, Lalit Lakhwani, Suyog Mehta, Sadhana Joglekar   +24 more
wiley   +1 more source