Results 81 to 90 of about 401,460 (242)

Understanding the Type 2 Immunity: An Evolving View Beyond Allergic Diseases

Allergy, EarlyView.
ABSTRACT Type 2 (T2) immunity is classically associated with defense against helminths and environmental threats, from a physiological perspective, and with allergies and eosinophilic inflammatory diseases, in a pathological sense. However, growing evidence reveals that T2 pathways also support other essential homeostatic functions, including tissue ...
Rodrigo Jiménez‐Saiz, Salvador Iborra, Carlos Blanco, Ruperto González‐Pérez, Emilio Nuñez‐Borque, Can Zeyneloglu, Huseyn Babayev, Ozlem Göksel, Tuncay Göksel, Musa Khaitov, Dmitry Kudlay, Yadong Gao, Mustafa Sevim, Marie‐Charlotte Brüggen, Oral Alpan, Ming Wang, Luo Zhang, María J. Torres, Mohamed Shamji, Mübeccel Akdis, Kari C. Nadeau, Ismail Ogulur, Cezmi A. Akdis   +22 more
wiley   +1 more source

Murine Models of Gastric Corpus PreneoplasiaSummary

Cellular and Molecular Gastroenterology and Hepatology, 2017
Intestinal-type gastric adenocarcinoma evolves in a field of pre-existing metaplasia. Over the past 20 years, a number of murine models have been developed to address aspects of the physiology and pathophysiology of metaplasia induction. Although none of
Christine P. Petersen, Jason C. Mills, James R. Goldenring   +2 more
doaj   +1 more source

Routine Preoperative Oesophagogastroduodenoscopy Before Roux‐En‐Y Gastric Bypass: A Retrospective Cohort Analysis From Queensland, Australia

ANZ Journal of Surgery, EarlyView.
Impact of routine POOGD with routine biopsies on surgical management in 423 patients undergoing RYGB. ABSTRACT Introduction The role of routine preoperative oesophagogastroduodenoscopy (POOGD) with routine biopsies prior to Roux‐en‐Y gastric bypass (RYGB) remains controversial.
Shahab Valizadehzare, Michael Hatzifotis
wiley   +1 more source

scRNA‐Seq in Gastric Cancer Reveals Macrophage‐Derived C1q as a Diagnostic Marker

Cancer Science, EarlyView.
Single‐cell sequencing of GC analyzed the tumor microenvironment and discovered the C1QA+ TAMs subpopulation with immunosuppressive function. The role of C1q in the prognosis and diagnosis of GC was demonstrated through plasma and tumor tissue from the GC cohort.
Saisai Gong, Yupeng Zhao, Sheng Yang, Tong Liu, Chengyun Li, Yun Zhou, Geyu Liang   +6 more
wiley   +1 more source

hTERT, MYC and TP53 deregulation in gastric preneoplastic lesions

BMC Gastroenterology, 2012
Background Gastric cancer is a serious public health problem in Northern Brazil and in the world due to its high incidence and mortality. Despite the severity of the disease, more research is needed to better understand the molecular events involved in ...
Silva Tanielly Cristina, Leal Mariana, Calcagno Danielle, de Souza Carolina Rosal, Khayat André, dos Santos Ney Pereira, Montenegro Raquel, Rabenhorst Silvia Helena, Nascimento Mayara, Assumpção Paulo, de Arruda Cardoso Smith Marília, Burbano Rommel   +11 more
doaj   +1 more source

Apoptosis and proliferation in Helicobacter pylori-associated gastric intestinal metaplasia

, 2001
Background: Imbalance between apoptosis and proliferation may be one of the mechanisms underlying H. pylori associated gastric carcinogenesis. Aim: To examine the cell kinetics of gastric intestinal metaplasia and the effect of H.
Go, MYY, Chan, FKL, Ma, PK, Yu, J, Leung, WK, To, KF, Sung, JJY   +6 more
core   +1 more source

Clinical and surgical findings in a mare with unilateral ovarian fibroleiomyoma and adhesions

Equine Veterinary Education, EarlyView.
Summary This case report describes the clinical presentation, ultrasonographic findings, surgical management and outcome of a 7‐year‐old Warmblood mare presented for recurrent colic, weight loss and poor performance. Rectal palpation identified a firm mass in the left caudal abdomen, which appeared on ultrasonography as a large, fluid‐filled, cyst‐like
N. Scilimati, P. Berni, E. Blanc, M. Di Pentima, F. Leonardi, S. Napoli, C. Palmieri, M. Ruggeri, R. Gialletti   +8 more
wiley   +1 more source

Mechanisms underpinning the progression of nondysplastic Barrett's oesophagus to cancer

The FEBS Journal, EarlyView.
Barrett's oesophagus confers a low but significant cancer risk. The condition is common but we do not have effective biomarkers to identify susceptible patients. We believe that there is no single factor that determines cancer risk and an understanding of the combinations of interactions (via gene expression and natural selection) between the Barrett's
Yannick H. Derwa, Meng‐Lay Lin, Stuart A. C. McDonald   +2 more
wiley   +1 more source

Rabeprazole suppressed gastric intestinal metaplasia through activation of GPX4-mediated ferroptosis

Frontiers in Pharmacology
BackgroundGastric intestinal metaplasia is a common pathological feature in patients with Helicobacter pylori (H. pylori) infection. Rabeprazole was widely used as the first-line regimen for H. pylori infectious treatment.
Jing Xie, Xinhua Liang, Fangfang Xie, Canxin Huang, Zijun Lin, Shuping Xie, Fangying Yang, Fengfeng Zheng, Lanlan Geng, Lanlan Geng, Wanfu Xu, Wanfu Xu, Sitang Gong, Sitang Gong, Li Xiang, Li Xiang   +15 more
doaj   +1 more source

Prevalence of barrett's esophagus, its relationship with chronic Helicobacter pylori-associated gastritis, atrophy and metaplasia of gastric mucosa

Клінічна та профілактична медицина, 2019
The aim - to identify the frequency of Helicobacter pylori infection, atrophic and metaplastic changes in the gastric mucosa in patients with Barrett's esophagus. Materials and methods.
T.V. Serha, O.G. Kuryk, V.A. Yakovenko, G.A. Solovyova, R.P. Tkachenko   +4 more
doaj   +1 more source