Results 81 to 90 of about 26,131 (235)

Efficacy and Safety of Elagolix Versus Dienogest for Treatment of Moderate‐to‐Severe Endometriosis Pain: A Phase III, Multicentric, Double‐Blind, Active‐Controlled, Non‐Inferiority Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To compare the efficacy, safety and tolerability of elagolix with dienogest in women with moderate‐to‐severe endometriosis‐associated pain. Design A multicentre, double‐blind, double‐dummy, randomised, parallel‐group, active‐controlled, non‐inferiority phase III study. Setting Nineteen clinical centres across India.
Sneha Bhoir, Jaldhara Patel, Tushar Palve, Mrinal Kanti Dash, Sweety Saigal, Gourisankar Kamilya, Shalini Srivastava, Kartikbhai Savalia, Tanusree Gupta, Deepa Choudhary, Manohar Rangaswamy, Vidya V Bhatt, Neena Gupta, Malathi Ponnuru, Parul Shah, Apurva Shetty, Shruti Saha, Reshma Quadros, Sucheta Pandit, Dipak Patil, Piyush Patel, Pravin Ghadge, Lalit Lakhwani, Suyog Mehta, Sadhana Joglekar   +24 more
wiley   +1 more source

Murine Models of Gastric Corpus PreneoplasiaSummary

Cellular and Molecular Gastroenterology and Hepatology, 2017
Intestinal-type gastric adenocarcinoma evolves in a field of pre-existing metaplasia. Over the past 20 years, a number of murine models have been developed to address aspects of the physiology and pathophysiology of metaplasia induction. Although none of
Christine P. Petersen, Jason C. Mills, James R. Goldenring   +2 more
doaj   +1 more source

A single centre multidisciplinary team retrospective review of fifty cases of robot‐assisted surgery for diaphragmatic and thoracic endometriosis

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Robot‐assisted multidisciplinary surgery enables safe, efficient, and comprehensive treatment of diaphragmatic and thoracic endometriosis. Evaluation of DTE in specialized centers, in a multidisciplinary fashion, allows for patient‐centered operative planning and could avoid missed disease or incomplete management.
Peter Barton‐Smith, Michal Kawka, Tom Routledge, Rupali Arora, Long R. Jiao   +4 more
wiley   +1 more source

Intestinal Metaplasia and Gastric Carcinoma [PDF]

, 1990
Previous studies have suggested that gastric carcinogenesis is a multistage process involving first gastritis, then intestinal metaplasia, dysplasia of increasing severity and finally carcinoma. The exact role of intestinal metaplasia in the histogenesis
Aitchison, Michael
core  

Intestinal Metaplasia Associated with Symptoms of Dyspepsia

, 2023
Abstract Background Peptic ulcer disease (PUD) and Helicobacter pylori (HP) are associated with dyspepsia, but the role of gastric intestinal metaplasia (IM) has not been described. The objective of this study is to examine the association between gastric IM and dyspepsia.
Viramontes, Omar, Martinez, Dalia, Somsouk, Ma   +2 more
openaire   +2 more sources

Seromucinous borderline ovarian tumors: Clinical and ultrasound characteristics and association with endometriosis

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Seromucinous borderline ovarian tumors frequently appear as unilateral, left‐sided cysts with ground‐glass echogenicity and moderately vascularized solid components. Their strong association with ipsilateral endometriosis provides crucial sonographic and clinical clues for an accurate preoperative diagnosis.
Simona Del Forno, Marisol Doglioli, Chiara Landolfo, Giovanna Palomba, Claudia Vicenzi, Matilde Antonelli, Lucia De Meis, Francesca Govoni, Roberto Paradisi, Diego Raimondo, Renato Seracchioli   +10 more
wiley   +1 more source

hTERT, MYC and TP53 deregulation in gastric preneoplastic lesions

BMC Gastroenterology, 2012
Background Gastric cancer is a serious public health problem in Northern Brazil and in the world due to its high incidence and mortality. Despite the severity of the disease, more research is needed to better understand the molecular events involved in ...
Silva Tanielly Cristina, Leal Mariana, Calcagno Danielle, de Souza Carolina Rosal, Khayat André, dos Santos Ney Pereira, Montenegro Raquel, Rabenhorst Silvia Helena, Nascimento Mayara, Assumpção Paulo, de Arruda Cardoso Smith Marília, Burbano Rommel   +11 more
doaj   +1 more source

The metalloproteinase ADAM17 promotes acute lung inflammatory responses during pancreatitis

British Journal of Pharmacology, EarlyView.
Background and Purpose Acute pancreatitis (AP) is a multifactorial upper gastrointestinal inflammatory disorder that in severe cases (~20% of all AP) is associated with substantial morbidity and mortality, the latter coincident with multiorgan dysfunction, particularly acute lung injury (ALI).
Shermin Chan, Karen Hon, Ruby E. Dawson, Teresa Weng, Jelena Solujic, Yu C. J. Chey, James D. Zuiani, Griffith B. Perkins, P. Toby Coates, Chris Drogemuller, Eddie Sanderlin, Lulu Huang, John Finnie, Stefan Rose‐John, Arash Badiei, Phan Nguyen, Brendan J. Jenkins, Mohamed I. Saad   +17 more
wiley   +1 more source

Rabeprazole suppressed gastric intestinal metaplasia through activation of GPX4-mediated ferroptosis

Frontiers in Pharmacology
BackgroundGastric intestinal metaplasia is a common pathological feature in patients with Helicobacter pylori (H. pylori) infection. Rabeprazole was widely used as the first-line regimen for H. pylori infectious treatment.
Jing Xie, Xinhua Liang, Fangfang Xie, Canxin Huang, Zijun Lin, Shuping Xie, Fangying Yang, Fengfeng Zheng, Lanlan Geng, Lanlan Geng, Wanfu Xu, Wanfu Xu, Sitang Gong, Sitang Gong, Li Xiang, Li Xiang   +15 more
doaj   +1 more source

Gastric Mucosal Molecular Alterations and Multimodal Field‐Based Risk Models for Gastric Cancer Development

Cancer Science, EarlyView.
DNA methylation in non‐neoplastic background gastric mucosa reflects cumulative inflammatory and exposure‐related field changes before cancer develops. Combining methylation with clinical, endoscopic, histological, and emerging multimodal information may refine calibrated gastric cancer risk prediction and support risk‐adapted personalized endoscopic ...
Genki Usui, Atsushi Kaneda
wiley   +1 more source